Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PumA-relB/COG3657-DUF971 |
| Location | 2451478..2452083 | Replicon | chromosome |
| Accession | NZ_CP006696 | ||
| Organism | Xylella fastidiosa subsp. sandyi Ann-1 | ||
Toxin (Protein)
| Gene name | PumA | Uniprot ID | B2I5N3 |
| Locus tag | D934_RS11475 | Protein ID | WP_004089252.1 |
| Coordinates | 2451478..2451774 (+) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | D934_RS11480 | Protein ID | WP_004089254.1 |
| Coordinates | 2451778..2452083 (+) | Length | 102 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D934_RS11445 | 2447164..2447712 | + | 549 | WP_024749081.1 | SocA family protein | - |
| D934_RS11450 | 2447672..2448268 | + | 597 | WP_024749080.1 | hypothetical protein | - |
| D934_RS11455 | 2448282..2448509 | + | 228 | WP_024749079.1 | hypothetical protein | - |
| D934_RS11460 | 2448510..2449673 | - | 1164 | WP_020851649.1 | phage tail protein | - |
| D934_RS11465 | 2449677..2450237 | - | 561 | WP_020851650.1 | DUF2612 domain-containing protein | - |
| D934_RS11470 | 2450234..2451379 | - | 1146 | WP_020851651.1 | baseplate J/gp47 family protein | - |
| D934_RS11475 | 2451478..2451774 | + | 297 | WP_004089252.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| D934_RS11480 | 2451778..2452083 | + | 306 | WP_004089254.1 | putative addiction module antidote protein | Antitoxin |
| D934_RS11485 | 2452094..2452447 | - | 354 | WP_020851652.1 | hypothetical protein | - |
| D934_RS11490 | 2452444..2453085 | - | 642 | WP_020851653.1 | phage-related protein | - |
| D934_RS11495 | 2453082..2453912 | - | 831 | WP_042836628.1 | hypothetical protein | - |
| D934_RS11500 | 2453909..2454226 | - | 318 | WP_020851655.1 | hypothetical protein | - |
| D934_RS11505 | 2454226..2454996 | - | 771 | WP_024749165.1 | hypothetical protein | - |
| D934_RS11510 | 2455054..2455380 | + | 327 | WP_004091353.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| D934_RS11515 | 2455377..2455658 | + | 282 | WP_004091355.1 | helix-turn-helix domain-containing protein | - |
| D934_RS14555 | 2455717..2456010 | - | 294 | Protein_2272 | hypothetical protein | - |
| D934_RS11520 | 2456012..2456233 | - | 222 | Protein_2273 | hypothetical protein | - |
| D934_RS11525 | 2456321..2456620 | + | 300 | WP_024749166.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| D934_RS11530 | 2456624..2456932 | + | 309 | WP_004085003.1 | putative addiction module antidote protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2428131..2468690 | 40559 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 10790.57 Da Isoelectric Point: 10.0509
>T45433 WP_004089252.1 NZ_CP006696:2451478-2451774 [Xylella fastidiosa subsp. sandyi Ann-1]
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQVRDIEQAKALAALWKD
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQVRDIEQAKALAALWKD
Download Length: 297 bp
>T45433 NZ_CP006696:2451478-2451774 [Xylella fastidiosa subsp. sandyi Ann-1]
ATGGTCGAACTCATCAAAACCAGCACTTTTGATGCTTGGATAAACAGCTTACGTGACCGCAAAGCAGCCGCCAGAATTCA
AGCGCGTCTTGATCGGCTCGCACTTGGCAATCCCGGCGACGTGAAGCCTGTGGGTGCTGGCATATCAGAAATGAGGATCG
ACCATGGGCCCGGATATCGGATCTATTTTATGAAGCATGGTGCAGTACTGATTCTCTTACTTTGCGGTGGCGATAAATCG
TCACAAGTACGAGATATAGAGCAGGCTAAGGCACTGGCTGCACTGTGGAAGGATTAG
ATGGTCGAACTCATCAAAACCAGCACTTTTGATGCTTGGATAAACAGCTTACGTGACCGCAAAGCAGCCGCCAGAATTCA
AGCGCGTCTTGATCGGCTCGCACTTGGCAATCCCGGCGACGTGAAGCCTGTGGGTGCTGGCATATCAGAAATGAGGATCG
ACCATGGGCCCGGATATCGGATCTATTTTATGAAGCATGGTGCAGTACTGATTCTCTTACTTTGCGGTGGCGATAAATCG
TCACAAGTACGAGATATAGAGCAGGCTAAGGCACTGGCTGCACTGTGGAAGGATTAG
Antitoxin
Download Length: 102 a.a. Molecular weight: 10983.37 Da Isoelectric Point: 5.0941
>AT45433 WP_004089254.1 NZ_CP006696:2451778-2452083 [Xylella fastidiosa subsp. sandyi Ann-1]
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSNDGNPSFS
TILKVAKALGLRMSFTPSSMS
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSNDGNPSFS
TILKVAKALGLRMSFTPSSMS
Download Length: 306 bp
>AT45433 NZ_CP006696:2451778-2452083 [Xylella fastidiosa subsp. sandyi Ann-1]
ATGAATAATGAGACTTTTAGTCGATACGACACCGCTGACTATCTCAAAACCGAAGAAGATATTGCGGCTTATATGGAAGC
CGTCATGGAAGAAGGTGGTAGGGATAATCCTGCTTTTATTGCACGGGCACTTGGTGCCGTCGCTCGTGCTCGTAATTTAA
GTCAGCTGGCTCGTGACGTTGGCATGTCCAGGCAAGGACTAGACAAGGCACTCTCTAACGACGGCAACCCAAGCTTCTCA
ACCATCTTAAAAGTGGCTAAAGCGCTTGGTTTACGGATGTCATTCACACCTTCCTCTATGAGTTAA
ATGAATAATGAGACTTTTAGTCGATACGACACCGCTGACTATCTCAAAACCGAAGAAGATATTGCGGCTTATATGGAAGC
CGTCATGGAAGAAGGTGGTAGGGATAATCCTGCTTTTATTGCACGGGCACTTGGTGCCGTCGCTCGTGCTCGTAATTTAA
GTCAGCTGGCTCGTGACGTTGGCATGTCCAGGCAAGGACTAGACAAGGCACTCTCTAACGACGGCAACCCAAGCTTCTCA
ACCATCTTAAAAGTGGCTAAAGCGCTTGGTTTACGGATGTCATTCACACCTTCCTCTATGAGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|