45378

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3415864..3416009 Replicon chromosome
Accession NZ_CP006659
Organism Klebsiella pneumoniae strain ATCC BAA-2146

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3415871..3415973 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3415864..3416009 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
kpn2146_RS17265 3411397..3412830 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
kpn2146_RS17270 3412946..3413185 + 240 WP_002911393.1 YebV family protein -
kpn2146_RS17275 3413283..3413474 + 192 WP_002911395.1 YebW family protein -
kpn2146_RS17280 3413471..3414124 - 654 WP_004189273.1 protein-serine/threonine phosphatase -
kpn2146_RS17285 3414281..3415249 + 969 WP_004151446.1 VirK/YbjX family protein -
kpn2146_RS31970 3415354..3415497 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3415864..3416009 + 146 - - Antitoxin
- 3415871..3415973 - 103 - - Toxin
kpn2146_RS17295 3416132..3416470 - 339 WP_004189269.1 YebY family protein -
kpn2146_RS17300 3416487..3417356 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
kpn2146_RS17305 3417360..3417734 - 375 WP_004151448.1 CopC domain-containing protein YobA -
kpn2146_RS17310 3417847..3418077 + 231 WP_002911406.1 DNA polymerase III subunit theta -
kpn2146_RS17315 3418156..3418815 + 660 WP_002911407.1 exodeoxyribonuclease X -
kpn2146_RS17320 3418819..3420879 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T45378 NZ_CP006659:c3415973-3415871 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT45378 NZ_CP006659:3415864-3416009 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References