Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1885006..1885277 Replicon chromosome
Accession NZ_CP006636
Organism Escherichia coli PCN061

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1885044..1885147 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1885006..1885277 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PCN061_RS09535 1882163..1883602 + 1440 WP_001338165.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
PCN061_RS09540 1883720..1883956 + 237 WP_001338166.1 DUF1480 family protein -
PCN061_RS09545 1884061..1884252 + 192 WP_001338167.1 YebW family protein -
PCN061_RS09550 1884253..1884909 - 657 WP_000812733.1 protein-serine/threonine phosphatase -
- 1885006..1885277 + 272 - - Antitoxin
- 1885044..1885147 - 104 - - Toxin
PCN061_RS09560 1885305..1885646 - 342 WP_000976472.1 YebY family protein -
PCN061_RS09565 1885659..1886531 - 873 WP_000879298.1 copper homeostasis membrane protein CopD -
PCN061_RS09570 1886535..1886909 - 375 WP_000255065.1 CopC domain-containing protein YobA -
PCN061_RS09575 1887048..1887278 + 231 WP_000916763.1 DNA polymerase III subunit theta -
PCN061_RS09580 1887380..1888036 + 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
PCN061_RS09585 1888060..1888722 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1876776..1908267 31491


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T45336 NZ_CP006636:c1885147-1885044 [Escherichia coli PCN061]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT45336 NZ_CP006636:1885006-1885277 [Escherichia coli PCN061]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References