Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2030720..2030988 Replicon chromosome
Accession NZ_CP006632
Organism Escherichia coli PCN033

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2030758..2030861 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2030720..2030988 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PPECC33_RS09985 2027877..2029316 + 1440 WP_001366375.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
PPECC33_RS09990 2029434..2029670 + 237 WP_001295499.1 DUF1480 family protein -
PPECC33_RS09995 2029775..2029966 + 192 WP_001296140.1 YebW family protein -
PPECC33_RS10000 2029967..2030623 - 657 WP_000812730.1 protein-serine/threonine phosphatase -
- 2030720..2030988 + 269 - - Antitoxin
- 2030758..2030861 - 104 - - Toxin
PPECC33_RS10010 2031018..2031359 - 342 WP_000976471.1 YebY family protein -
PPECC33_RS10015 2031372..2032244 - 873 WP_000879330.1 copper homeostasis membrane protein CopD -
PPECC33_RS10020 2032248..2032622 - 375 WP_000204700.1 CopC domain-containing protein YobA -
PPECC33_RS10025 2032761..2032991 + 231 WP_000916763.1 DNA polymerase III subunit theta -
PPECC33_RS10030 2033093..2033749 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
PPECC33_RS10035 2033773..2034435 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2014169..2054782 40613


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T45303 NZ_CP006632:c2030861-2030758 [Escherichia coli PCN033]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT45303 NZ_CP006632:2030720-2030988 [Escherichia coli PCN033]
AAAGTCAGCGAAAGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGGGGTCATTAGCTTAAATGTTAAAAACCGCCTG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References