Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsdAT/- |
Location | 2138792..2139306 | Replicon | chromosome |
Accession | NZ_CP006630 | ||
Organism | Staphylococcus aureus subsp. aureus SA268 |
Toxin (Protein)
Gene name | TsdT | Uniprot ID | T1YA99 |
Locus tag | SA268_RS10790 | Protein ID | WP_000581792.1 |
Coordinates | 2138792..2139001 (-) | Length | 70 a.a. |
Antitoxin (Protein)
Gene name | TsdA | Uniprot ID | A0A0D1GBN9 |
Locus tag | SA268_RS10795 | Protein ID | WP_000138934.1 |
Coordinates | 2139013..2139306 (-) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SA268_RS10770 | 2134300..2135658 | - | 1359 | WP_000611468.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
SA268_RS10775 | 2135673..2136743 | - | 1071 | WP_000159641.1 | D-alanine--D-alanine ligase | - |
SA268_RS10780 | 2137061..2138263 | + | 1203 | WP_001109939.1 | rod shape-determining protein RodA | - |
SA268_RS10785 | 2138527..2138664 | - | 138 | WP_000828354.1 | hypothetical protein | - |
SA268_RS10790 | 2138792..2139001 | - | 210 | WP_000581792.1 | heavy-metal-associated domain-containing protein | Toxin |
SA268_RS10795 | 2139013..2139306 | - | 294 | WP_000138934.1 | copper-sensing transcriptional repressor CsoR | Antitoxin |
SA268_RS10800 | 2139472..2140956 | + | 1485 | WP_000571549.1 | cardiolipin synthase | - |
SA268_RS10805 | 2140984..2141631 | + | 648 | WP_001187610.1 | HD domain-containing protein | - |
SA268_RS10815 | 2142446..2143318 | - | 873 | WP_000725802.1 | membrane protein insertase YidC | - |
SA268_RS10820 | 2143404..2144045 | - | 642 | WP_000483147.1 | thiamine phosphate synthase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 70 a.a. Molecular weight: 7843.77 Da Isoelectric Point: 4.1008
>T45289 WP_000581792.1 NZ_CP006630:c2139001-2138792 [Staphylococcus aureus subsp. aureus SA268]
MIHQNTIYTAGIETEEQVSQLTERISNMIGVHQVNINIIDGQVTVSYETPANLNSIEKEIYDEGYKIVF
MIHQNTIYTAGIETEEQVSQLTERISNMIGVHQVNINIIDGQVTVSYETPANLNSIEKEIYDEGYKIVF
Download Length: 210 bp
>T45289 NZ_CP006630:c2139001-2138792 [Staphylococcus aureus subsp. aureus SA268]
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATAGACGGTCAAGTAACTGTATCGTATGAAACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATCTATGATGAAGGATACAAAATTGTATTTTAG
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATAGACGGTCAAGTAACTGTATCGTATGAAACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATCTATGATGAAGGATACAAAATTGTATTTTAG
Antitoxin
Download Length: 98 a.a. Molecular weight: 11185.77 Da Isoelectric Point: 6.2243
>AT45289 WP_000138934.1 NZ_CP006630:c2139306-2139013 [Staphylococcus aureus subsp. aureus SA268]
MTEQDNAHHSEQIKTNLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVATKLLEQHMKSCIMNKVNQGAQ
EEAMEELLVTFQKLIKD
MTEQDNAHHSEQIKTNLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVATKLLEQHMKSCIMNKVNQGAQ
EEAMEELLVTFQKLIKD
Download Length: 294 bp
>AT45289 NZ_CP006630:c2139306-2139013 [Staphylococcus aureus subsp. aureus SA268]
ATGACTGAACAAGATAATGCACATCATTCTGAACAAATAAAAACGAATCTTAAATCACGTTTAAATCGAATTGAAGGACA
AGTGAGAGCGATTAATCGCATGATTGAAGAAGATGTCTATTGTGATGATGTCCTTACGCAAATAAGAGCGACACGTTCGG
CGTTAAACAGTGTTGCGACAAAGTTATTAGAACAACATATGAAAAGTTGTATTATGAATAAAGTTAATCAAGGTGCTCAG
GAAGAGGCAATGGAAGAGTTATTAGTGACTTTTCAAAAATTGATTAAAGACTAA
ATGACTGAACAAGATAATGCACATCATTCTGAACAAATAAAAACGAATCTTAAATCACGTTTAAATCGAATTGAAGGACA
AGTGAGAGCGATTAATCGCATGATTGAAGAAGATGTCTATTGTGATGATGTCCTTACGCAAATAAGAGCGACACGTTCGG
CGTTAAACAGTGTTGCGACAAAGTTATTAGAACAACATATGAAAAGTTGTATTATGAATAAAGTTAATCAAGGTGCTCAG
GAAGAGGCAATGGAAGAGTTATTAGTGACTTTTCAAAAATTGATTAAAGACTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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