Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1038090..1038843 Replicon chromosome
Accession NZ_CP006580
Organism Enterobacter ludwigii strain P101

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag M942_RS05260 Protein ID WP_025203211.1
Coordinates 1038090..1038467 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag M942_RS05265 Protein ID WP_204247304.1
Coordinates 1038517..1038843 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M942_RS05230 1033395..1033658 - 264 WP_025203205.1 type II toxin-antitoxin system ParD family antitoxin -
M942_RS05235 1033752..1034597 - 846 WP_025203206.1 DUF4942 domain-containing protein -
M942_RS05240 1034678..1034881 - 204 WP_025203207.1 DUF957 domain-containing protein -
M942_RS05245 1035143..1036156 + 1014 WP_025203208.1 hypothetical protein -
M942_RS05250 1036204..1037304 - 1101 WP_025203209.1 DNA cytosine methyltransferase -
M942_RS05255 1037602..1038093 - 492 WP_025203210.1 hypothetical protein -
M942_RS05260 1038090..1038467 - 378 WP_025203211.1 TA system toxin CbtA family protein Toxin
M942_RS05265 1038517..1038843 - 327 WP_204247304.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
M942_RS05270 1038900..1039121 - 222 WP_025203213.1 DUF987 domain-containing protein -
M942_RS05275 1039142..1039621 - 480 WP_025203214.1 DNA repair protein RadC -
M942_RS05280 1039632..1040117 - 486 WP_025203215.1 antirestriction protein -
M942_RS26505 1040134..1040388 - 255 WP_071842184.1 hypothetical protein -
M942_RS05285 1040388..1041206 - 819 WP_025203216.1 DUF945 domain-containing protein -
M942_RS05290 1041312..1041545 - 234 WP_025203217.1 DUF905 domain-containing protein -
M942_RS05295 1041601..1041822 - 222 WP_025203218.1 hypothetical protein -
M942_RS05300 1041894..1042256 - 363 WP_025203219.1 hypothetical protein -
M942_RS05305 1042341..1042805 - 465 WP_025203220.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1028027..1067470 39443


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(4-103)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13964.93 Da        Isoelectric Point: 6.7096

>T45267 WP_025203211.1 NZ_CP006580:c1038467-1038090 [Enterobacter ludwigii]
MKTQPVPPTREALPRPSPVAIWQCLLSHLLDRHYGLTLNDTPFGSDDVIQEHIDAGISLCDAVNFIVEKYDLVRTDRRGF
TVMEQSPFISSIDILRARRATGLMTRSGYKAVTDITSGKYSGEVQ

Download         Length: 378 bp

>T45267 NZ_CP006580:c1038467-1038090 [Enterobacter ludwigii]
ATGAAAACACAACCTGTTCCCCCGACACGGGAGGCTTTGCCACGCCCGTCACCCGTGGCTATCTGGCAGTGCCTCCTGAG
CCACCTGCTGGACCGTCACTACGGTCTGACGTTAAACGACACGCCGTTTGGCAGCGATGACGTCATTCAGGAGCATATCG
ACGCCGGAATATCACTGTGCGACGCGGTCAATTTTATCGTCGAAAAGTACGATCTAGTACGTACCGATCGCCGTGGTTTC
ACGGTGATGGAGCAGTCACCGTTTATCAGCAGCATCGATATTCTTCGCGCCCGTAGAGCAACCGGGCTGATGACCCGCAG
CGGGTACAAAGCCGTTACCGACATCACCAGCGGCAAATATAGCGGGGAGGTCCAGTGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12112.83 Da        Isoelectric Point: 6.4674

>AT45267 WP_204247304.1 NZ_CP006580:c1038843-1038517 [Enterobacter ludwigii]
ITEPWWGLKRNITPCFGTRLVQEGNRLHYLADRTSITGTFSDADLRHLDQAFPLLLKQLELMLTSGELTPRHQHSVTLYV
KGLTCDADTLGSCGYLYLAIYPTAATTE

Download         Length: 327 bp

>AT45267 NZ_CP006580:c1038843-1038517 [Enterobacter ludwigii]
ATCACCGAACCCTGGTGGGGGCTTAAACGCAATATCACACCCTGTTTTGGCACTCGTCTGGTGCAGGAGGGTAACCGGCT
GCATTACCTCGCTGACCGCACCAGTATCACCGGGACCTTCAGCGATGCAGATTTACGCCATCTGGACCAGGCGTTTCCGC
TGCTGTTGAAGCAACTTGAACTGATGCTCACCAGCGGTGAGCTCACTCCCCGCCATCAGCACAGTGTGACCCTGTATGTA
AAAGGGCTGACCTGCGACGCGGATACCCTCGGCAGTTGTGGTTATCTCTATCTCGCAATTTACCCGACAGCTGCAACAAC
CGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References