Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Hha-TomB/- |
Location | 4327980..4328589 | Replicon | chromosome |
Accession | NZ_CP006568 | ||
Organism | Candidatus Sodalis pierantonius str. SOPE |
Toxin (Protein)
Gene name | Hha | Uniprot ID | W0HVX7 |
Locus tag | SOPEG_RS21425 | Protein ID | WP_011410544.1 |
Coordinates | 4328386..4328589 (+) | Length | 68 a.a. |
Antitoxin (Protein)
Gene name | TomB | Uniprot ID | W0I0J8 |
Locus tag | SOPEG_RS21420 | Protein ID | WP_025246875.1 |
Coordinates | 4327980..4328339 (+) | Length | 120 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SOPEG_RS21410 | 4323724..4326888 | + | 3165 | WP_025246873.1 | multidrug efflux RND transporter permease subunit | - |
SOPEG_RS21415 | 4327040..4327297 | + | 258 | WP_025246874.1 | type B 50S ribosomal protein L31 | - |
SOPEG_RS25645 | 4327318..4327458 | + | 141 | WP_071882278.1 | type B 50S ribosomal protein L36 | - |
SOPEG_RS21420 | 4327980..4328339 | + | 360 | WP_025246875.1 | Hha toxicity modulator TomB | Antitoxin |
SOPEG_RS21425 | 4328386..4328589 | + | 204 | WP_011410544.1 | hemolysin expression modulator Hha | Toxin |
SOPEG_RS21430 | 4329383..4329712 | + | 330 | WP_025246876.1 | MGMT family protein | - |
SOPEG_RS21435 | 4330033..4330593 | - | 561 | WP_025246877.1 | YbaY family lipoprotein | - |
SOPEG_RS21440 | 4330616..4331212 | - | 597 | Protein_4339 | IS256 family transposase | - |
SOPEG_RS21450 | 4331285..4332492 | + | 1208 | Protein_4340 | IS256 family transposase | - |
SOPEG_RS26830 | 4332526..4333147 | - | 622 | Protein_4341 | IS256-like element ISSoEn2 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 68 a.a. Molecular weight: 8150.53 Da Isoelectric Point: 8.8913
>T45243 WP_011410544.1 NZ_CP006568:4328386-4328589 [Candidatus Sodalis pierantonius str. SOPE]
MKKIDYLMRLRKCRTLETLERVIEKNKYELSDDELEIFNSAADHRLAELTMNKLYDKVPVSVWKYVR
MKKIDYLMRLRKCRTLETLERVIEKNKYELSDDELEIFNSAADHRLAELTMNKLYDKVPVSVWKYVR
Download Length: 204 bp
>T45243 NZ_CP006568:4328386-4328589 [Candidatus Sodalis pierantonius str. SOPE]
ATGAAAAAGATCGACTATTTAATGCGCTTGAGGAAGTGCCGAACGCTGGAAACCCTCGAGCGTGTGATTGAAAAAAACAA
ATATGAACTGTCTGATGATGAACTGGAGATATTCAATTCCGCCGCCGATCATCGCCTGGCGGAACTGACCATGAACAAGC
TGTACGACAAAGTTCCAGTTTCTGTCTGGAAGTATGTACGCTAA
ATGAAAAAGATCGACTATTTAATGCGCTTGAGGAAGTGCCGAACGCTGGAAACCCTCGAGCGTGTGATTGAAAAAAACAA
ATATGAACTGTCTGATGATGAACTGGAGATATTCAATTCCGCCGCCGATCATCGCCTGGCGGAACTGACCATGAACAAGC
TGTACGACAAAGTTCCAGTTTCTGTCTGGAAGTATGTACGCTAA
Antitoxin
Download Length: 120 a.a. Molecular weight: 13973.50 Da Isoelectric Point: 4.4687
>AT45243 WP_025246875.1 NZ_CP006568:4327980-4328339 [Candidatus Sodalis pierantonius str. SOPE]
MDEYSPKRYDIAQLKYLCENLYDEGIASLGDSYHGWVNDPSSAVNLQLNELIEHIAANIVIFKLKYHNESELTDQVETFL
DDTFTLFSSYGINNYDIQRWRRSRRRLFGTFSETELCTT
MDEYSPKRYDIAQLKYLCENLYDEGIASLGDSYHGWVNDPSSAVNLQLNELIEHIAANIVIFKLKYHNESELTDQVETFL
DDTFTLFSSYGINNYDIQRWRRSRRRLFGTFSETELCTT
Download Length: 360 bp
>AT45243 NZ_CP006568:4327980-4328339 [Candidatus Sodalis pierantonius str. SOPE]
ATGGATGAGTATTCACCCAAACGCTACGATATTGCGCAATTGAAATACCTGTGTGAAAATCTCTATGATGAAGGCATTGC
CAGTCTGGGTGACAGCTATCATGGTTGGGTAAATGACCCAAGTTCCGCCGTCAATTTGCAGCTTAACGAATTAATTGAGC
ACATAGCGGCGAATATTGTCATCTTCAAACTTAAATACCATAATGAAAGTGAGCTTACCGATCAGGTTGAAACCTTTTTA
GACGATACTTTTACCCTGTTCAGTAGCTATGGCATCAATAATTACGATATCCAGCGCTGGCGTCGCAGCCGCAGGCGTTT
ATTCGGAACATTCTCGGAGACAGAGCTCTGTACAACCTGA
ATGGATGAGTATTCACCCAAACGCTACGATATTGCGCAATTGAAATACCTGTGTGAAAATCTCTATGATGAAGGCATTGC
CAGTCTGGGTGACAGCTATCATGGTTGGGTAAATGACCCAAGTTCCGCCGTCAATTTGCAGCTTAACGAATTAATTGAGC
ACATAGCGGCGAATATTGTCATCTTCAAACTTAAATACCATAATGAAAGTGAGCTTACCGATCAGGTTGAAACCTTTTTA
GACGATACTTTTACCCTGTTCAGTAGCTATGGCATCAATAATTACGATATCCAGCGCTGGCGTCGCAGCCGCAGGCGTTT
ATTCGGAACATTCTCGGAGACAGAGCTCTGTACAACCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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