Detailed information of TA system TA045239

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PhoH-LOG/-
• Location: 1569678..1571990
• Replicon: chromosome
• Accession: NZ_CP006271
• Organism: Synechococcus sp. KORDI-52 strain KORDI 52

Toxin (Protein)

• Gene name: PhoH
• Uniprot ID: -
• Locus tag: KR52_RS07915
• Protein ID: WP_038557070.1
• Coordinates: 1569678..1571066 (+)
• Length: 463 a.a.

Antitoxin (Protein)

• Gene name: LOG
• Uniprot ID: -
• Locus tag: KR52_RS07920
• Protein ID: WP_156957648.1
• Coordinates: 1571091..1571990 (+)
• Length: 300 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KR52_RS07895	1565458..1565631	-	174	Protein_1587	phycobilisome linker polypeptide, C-phycoerythrin class II-associated protein	-
KR52_RS07900	1565708..1565977	-	270	WP_038554447.1	DUF1651 domain-containing protein	-
KR52_RS13670	1567282..1567515	-	234	WP_071840271.1	hypothetical protein	-
KR52_RS14275	1567746..1568144	-	399	WP_156957647.1	hypothetical protein	-
KR52_RS07915	1569678..1571066	+	1389	WP_038557070.1	PhoH family protein	Toxin
KR52_RS07920	1571091..1571990	+	900	WP_156957648.1	LOG family protein	Antitoxin
KR52_RS07925	1572297..1572518	-	222	WP_038554457.1	DUF2811 domain-containing protein	-
KR52_RS07930	1572974..1573165	-	192	WP_038554460.1	hypothetical protein	-
KR52_RS14770	1573193..1573369	-	177	WP_173402207.1	hypothetical protein	-
KR52_RS14620	1573597..1573737	+	141	WP_162175596.1	hypothetical protein	-
KR52_RS07935	1574128..1576299	+	2172	WP_038557073.1	mechanosensitive ion channel	-
KR52_RS14280	1576673..1576990	-	318	WP_156957649.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-150)

Antitoxin

• LOG family (158-286)

Sequences

Toxin

Protein

• Length: 463 a.a.
• Molecular weight: 51120.24 Da
• Isoelectric Point: 6.1222

>T45239 WP_038557070.1 NZ_CP006271:1569678-1571066 [Synechococcus sp. KORDI-52]
MKDKIVVLDTNVLLHDPEAPHRFGDLRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSYRARGSLADGVPIEGTNNG
LLQVVFCQAQALNALPAELQGGGGDNNILAVALEQMRCSGLKQPPEVVLISKDINLRIKADAVGLKAEDYVNDKVSIEDL
YSGFREISTDAETIKILHDQDELPVEAVTDPDRQHLQANEGVVLVDQHNNSHTLLARHHPNSNTIKPLQWLNRAHLGRIK
ARNREQSFALDLLLDPFVALVTLVGKAGTGKTLLAIAAGLHQVADTHHYARLLVTRPPISLGNDIGYLPGTLEEKLGPWM
KPIIDNIDFITGSSTREDFEQTKKQRHREPRNAWADLQGMGLLEVEAINTIRGRSIPNQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDADSNGLTWLVDKLKGQPLVGHMTLTKGERSELAELAANIL

Nucleotide

• Length: 1389 bp

>T45239 NZ_CP006271:1569678-1571066 [Synechococcus sp. KORDI-52]
ATGAAAGATAAAATTGTCGTTCTCGACACGAATGTGCTACTTCACGATCCTGAAGCTCCACATCGCTTTGGAGATCTGCG
GGTTGTGATCCCCATGCAGGTGGTCGAAGAAATTGACCGCTTCAAAAAAGATCATTCTGAAAAAGGCCGGAACGCTCGGC
GGATTTCAAGGCTTCTCGATTCCTATCGAGCTCGTGGAAGTCTTGCTGACGGTGTTCCTATTGAGGGTACGAACAACGGC
CTGCTTCAGGTGGTTTTCTGTCAGGCCCAAGCCCTCAACGCCTTACCAGCAGAGCTTCAGGGCGGCGGCGGCGACAACAA
CATCCTTGCCGTGGCTCTGGAGCAGATGCGGTGCAGTGGGCTGAAACAGCCCCCAGAAGTTGTGCTGATCAGCAAAGACA
TCAACCTGAGAATCAAGGCCGATGCGGTGGGACTGAAAGCTGAGGACTACGTCAACGACAAGGTTTCGATTGAAGATCTC
TATTCAGGTTTCCGTGAAATCAGCACCGATGCGGAGACGATCAAGATCCTGCATGACCAGGATGAGCTGCCTGTGGAGGC
TGTCACCGATCCCGACCGGCAGCATCTCCAGGCCAATGAAGGCGTTGTACTGGTGGATCAGCACAACAACAGCCATACCC
TGCTAGCCCGGCACCACCCCAACAGCAACACGATCAAACCGCTGCAATGGCTGAATCGAGCCCATTTGGGCCGCATCAAA
GCGAGAAACCGTGAACAGAGCTTCGCGCTGGATCTGCTGCTCGATCCATTCGTCGCGCTGGTGACCCTGGTGGGCAAGGC
AGGCACAGGCAAAACGCTTCTGGCCATCGCTGCTGGTTTGCACCAGGTGGCCGATACCCATCACTACGCTCGTCTTCTGG
TGACGCGTCCGCCAATCTCCCTCGGCAACGACATCGGCTATCTCCCCGGCACTCTTGAGGAAAAACTCGGCCCCTGGATG
AAGCCGATCATTGACAACATTGACTTCATCACCGGTTCATCCACTCGCGAGGACTTTGAGCAGACGAAGAAGCAGCGGCA
CCGCGAACCACGCAACGCCTGGGCCGACCTGCAAGGCATGGGCTTGTTGGAGGTTGAAGCGATCAACACCATCCGCGGCC
GATCCATTCCCAATCAGTTCCTGGTGGTGGATGAGGCGCAGAACCTGACACCCCTTGAAGTGAAGACGATCGTCACGCGG
GTGGGCGAAGGAACCAAGGTTGTTTTCACCGGTGATCCATATCAAATCGACAACCCCTATGTGGATGCCGACAGCAATGG
GCTCACCTGGCTCGTGGACAAACTCAAAGGTCAGCCCCTGGTGGGACACATGACCCTTACGAAAGGCGAGCGCAGTGAAC
TGGCTGAATTGGCGGCCAACATCCTCTGA

Antitoxin

Protein

• Length: 300 a.a.
• Molecular weight: 33114.98 Da
• Isoelectric Point: 6.3795

>AT45239 WP_156957648.1 NZ_CP006271:1571091-1571990 [Synechococcus sp. KORDI-52]
MKIGHMTRFTATSTPEHVNLDAILNSPTYTIAHEDQDLLNSNEMRGVRMLLEITKPDLHLDMAGIESTIIVFGGARIVDK
ATAAAKLVKAKKCLSEDPDSPTLKRALTHAKHLLHLSRFYEAARHFAYLASQHGRCTKGQSHGCSSHVIVTGGGPGIMEA
ANRGAFEAGCRSIGLNITLPFEQHPNPYITPDLCFKFNYFSLRKFHFVMRSVGAILFPGGFGTLDELFELLTLRQVGTKG
SMPIVLFGTDFWTKLVDFEVLAEMGLIADDDLDLIHFSDTAEEAWEFIRRCTCAEPEDS

Nucleotide

• Length: 900 bp

>AT45239 NZ_CP006271:1571091-1571990 [Synechococcus sp. KORDI-52]
ATGAAAATTGGACACATGACTCGATTTACAGCAACTTCAACACCTGAGCACGTCAATCTGGATGCCATTCTGAATTCCCC
CACTTACACAATTGCTCATGAAGATCAAGACTTGTTGAACAGCAACGAAATGCGTGGTGTACGCATGCTGCTTGAAATCA
CCAAGCCGGATCTGCATCTCGACATGGCCGGGATTGAATCGACGATCATTGTTTTTGGTGGTGCCAGGATCGTCGACAAA
GCCACAGCTGCAGCGAAGCTGGTAAAAGCCAAGAAGTGCCTGAGCGAAGATCCTGATTCTCCAACTCTGAAAAGAGCATT
AACCCATGCCAAACATTTGTTGCACCTGTCTCGTTTTTATGAGGCAGCCCGACACTTCGCTTATCTGGCTTCCCAGCACG
GGCGGTGCACTAAGGGACAAAGCCATGGCTGCTCATCCCATGTGATCGTGACTGGTGGTGGGCCGGGAATCATGGAAGCT
GCCAACCGTGGTGCCTTTGAGGCCGGCTGTCGCTCGATCGGGCTGAATATTACGCTTCCATTTGAGCAACATCCCAATCC
CTACATCACCCCCGATCTTTGTTTCAAGTTCAATTACTTCTCTCTTCGCAAATTCCATTTTGTGATGCGCTCCGTTGGAG
CCATTTTGTTCCCAGGTGGTTTCGGCACCCTTGATGAATTGTTTGAGCTGCTGACCTTGAGGCAAGTGGGCACCAAGGGA
AGCATGCCCATTGTCCTCTTTGGAACAGATTTCTGGACCAAGCTTGTCGACTTTGAGGTCCTCGCTGAGATGGGATTGAT
CGCAGACGATGACCTCGACCTGATTCATTTTTCGGATACTGCAGAAGAGGCCTGGGAGTTCATCCGTCGTTGTACCTGTG
CCGAGCCTGAGGACAGCTGA