Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 4008785..4009298 Replicon chromosome
Accession NZ_CP006256
Organism Pseudomonas syringae pv. syringae HS191

Toxin (Protein)


Gene name relE Uniprot ID A0A0P9GC66
Locus tag PSYRH_RS17190 Protein ID WP_003423365.1
Coordinates 4009014..4009298 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3M4E5F0
Locus tag PSYRH_RS17185 Protein ID WP_024648170.1
Coordinates 4008785..4009024 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSYRH_RS17165 4004922..4005707 + 786 WP_003396313.1 hypothetical protein -
PSYRH_RS17170 4005862..4006770 - 909 WP_024662002.1 DUF808 domain-containing protein -
PSYRH_RS17175 4006917..4007423 - 507 WP_003315203.1 Lrp/AsnC family transcriptional regulator -
PSYRH_RS17180 4007610..4008626 + 1017 WP_003423368.1 1-aminocyclopropane-1-carboxylate deaminase -
PSYRH_RS17185 4008785..4009024 + 240 WP_024648170.1 CopG family ribbon-helix-helix protein Antitoxin
PSYRH_RS17190 4009014..4009298 + 285 WP_003423365.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSYRH_RS17195 4009333..4010187 - 855 WP_003423353.1 LysR family transcriptional regulator -
PSYRH_RS17200 4010262..4011194 + 933 WP_024662003.1 DMT family transporter -
PSYRH_RS17205 4011370..4013298 - 1929 WP_024665697.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10632.34 Da        Isoelectric Point: 10.4249

>T45198 WP_003423365.1 NZ_CP006256:4009014-4009298 [Pseudomonas syringae pv. syringae HS191]
MQVEWLKTALKNLDEEAAYIALDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHTRRQSPPVW

Download         Length: 285 bp

>T45198 NZ_CP006256:4009014-4009298 [Pseudomonas syringae pv. syringae HS191]
ATGCAGGTTGAGTGGCTCAAAACAGCACTAAAGAATCTGGATGAGGAGGCAGCGTATATCGCACTGGACAATCCAGCTGC
TGCCGCTGCTTTCGTGAAAGCCATTCAATCAAGCGTAACGCAGCTCGCGAGCTTTCCCGCCATGGGCCGGGAAGGACGGA
TTGCCGGAACCAGAGAATGGCCTCTGCCAGACCTGCCTTACCTGATTCCATATCGCATCCGTAGCGGCCGACTACAGGTT
CTACGGATTTTCCACACCAGAAGACAATCGCCACCCGTGTGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8715.80 Da        Isoelectric Point: 4.4354

>AT45198 WP_024648170.1 NZ_CP006256:4008785-4009024 [Pseudomonas syringae pv. syringae HS191]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASQEDVKAVMDKWSGNAG

Download         Length: 240 bp

>AT45198 NZ_CP006256:4008785-4009024 [Pseudomonas syringae pv. syringae HS191]
ATGTCCACAATGTCTCTACGTCTGCCGGACGAAATGGCAGATACCCTTGCACACCTTGCAAAGGCGACCGGGCGCAGCAA
GTCATTTTTGGCCCTCGACGCGCTCCGCGAATACCTGACACGCGAGGCTTGGCAGATTGCCGAAATTCAGCGTGCCATCG
AAGAAGCCGACGCCGGCGAGTTCGCAAGCCAAGAAGACGTAAAAGCTGTCATGGACAAATGGTCAGGCAATGCAGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9GC66

Antitoxin

Source ID Structure
AlphaFold DB A0A3M4E5F0

References