Detailed information of TA system TA045197

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 2721288..2721789
• Replicon: chromosome
• Accession: NZ_CP006256
• Organism: Pseudomonas syringae pv. syringae HS191

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PSYRH_RS12035
• Protein ID: WP_080348702.1
• Coordinates: 2721288..2721614 (-)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A6B2AS17
• Locus tag: PSYRH_RS12040
• Protein ID: WP_024661521.1
• Coordinates: 2721604..2721789 (-)
• Length: 62 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PSYRH_RS12035	2721288..2721614	-	327	WP_080348702.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PSYRH_RS12040	2721604..2721789	-	186	WP_024661521.1	hypothetical protein	Antitoxin
PSYRH_RS12045	2721840..2722141	-	302	Protein_2416	arylsulfatase regulator	-
PSYRH_RS12050	2722234..2722868	-	635	Protein_2417	recombinase family protein	-
PSYRH_RS12060	2723649..2724311	-	663	WP_046719344.1	XRE family transcriptional regulator	-
PSYRH_RS12065	2724399..2724587	+	189	WP_024663636.1	hypothetical protein	-
PSYRH_RS28070	2724653..2725413	+	761	Protein_2420	SGNH/GDSL hydrolase family protein	-
PSYRH_RS26875	2725420..2725651	+	232	Protein_2421	hypothetical protein	-
PSYRH_RS12075	2725736..2726542	-	807	WP_003314822.1	cytochrome c	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (37-107)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 12207.90 Da
• Isoelectric Point: 4.8562

>T45197 WP_080348702.1 NZ_CP006256:c2721614-2721288 [Pseudomonas syringae pv. syringae HS191]
VLVEWLPQALEALEEIAGYLAERNPYAAEQMQATLGYLAERNPYAAEQMQATLEATVEALPLHPYIHRPGRVPGTREAVV
HPNYLVVYRVGTERISILDVLHARQEYP

Nucleotide

• Length: 327 bp

>T45197 NZ_CP006256:c2721614-2721288 [Pseudomonas syringae pv. syringae HS191]
GTGCTAGTTGAGTGGCTTCCACAAGCTTTGGAGGCACTGGAGGAAATCGCCGGCTACCTAGCCGAGCGCAACCCTTATGC
TGCCGAGCAGATGCAGGCCACCCTCGGCTACCTAGCCGAGCGCAACCCTTATGCTGCCGAGCAGATGCAGGCCACCCTTG
AGGCCACGGTCGAGGCTCTCCCCCTGCACCCTTACATCCACCGTCCCGGCCGTGTTCCAGGAACGCGCGAAGCGGTTGTG
CATCCCAACTACCTGGTTGTCTACCGCGTCGGTACAGAGCGCATCAGCATCTTGGACGTCCTGCACGCCCGCCAAGAGTA
CCCCTAG

Antitoxin

Protein

• Length: 62 a.a.
• Molecular weight: 7268.20 Da
• Isoelectric Point: 7.0125

>AT45197 WP_024661521.1 NZ_CP006256:c2721789-2721604 [Pseudomonas syringae pv. syringae HS191]
MSIQLDPRVSEFETQEQADNYDRWFRQRIEHSLADPRPPVPLDEAMARVRAMIEAKRRRAS

Nucleotide

• Length: 186 bp

>AT45197 NZ_CP006256:c2721789-2721604 [Pseudomonas syringae pv. syringae HS191]
ATGAGCATTCAACTTGACCCTCGCGTCTCGGAGTTCGAGACCCAGGAACAGGCCGACAATTACGACCGTTGGTTTCGCCA
GCGTATCGAGCACAGTTTGGCCGATCCGCGTCCACCCGTGCCGCTCGATGAAGCAATGGCTCGCGTCAGAGCCATGATCG
AAGCAAAGCGCCGCCGTGCTAGTTGA

Structures

Antitoxin

• AlphaFold DB: A0A6B2AS17