Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 30966..31488 Replicon plasmid unnamed
Accession NZ_CP005994
Organism Salmonella enterica subsp. enterica serovar Heidelberg str. CFSAN002064

Toxin (Protein)


Gene name relE Uniprot ID G3CAN5
Locus tag CFSAN002064_RS00155 Protein ID WP_000220560.1
Coordinates 31207..31488 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G3CAG1
Locus tag CFSAN002064_RS00150 Protein ID WP_000121743.1
Coordinates 30966..31217 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFSAN002064_RS00125 26637..26918 + 282 WP_001185482.1 hypothetical protein -
CFSAN002064_RS00130 26943..27920 + 978 WP_001269910.1 hypothetical protein -
CFSAN002064_RS00135 27917..28342 - 426 WP_000202944.1 hypothetical protein -
CFSAN002064_RS00140 28410..28856 - 447 WP_001074386.1 hypothetical protein -
CFSAN002064_RS00145 28896..29732 - 837 WP_001050931.1 replication initiation protein -
CFSAN002064_RS00150 30966..31217 + 252 WP_000121743.1 plasmid stabilization protein Antitoxin
CFSAN002064_RS00155 31207..31488 + 282 WP_000220560.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFSAN002064_RS00160 31634..31957 + 324 WP_001181903.1 hypothetical protein -
CFSAN002064_RS00165 32002..32247 + 246 WP_000356547.1 hypothetical protein -
CFSAN002064_RS00170 32237..32452 + 216 WP_001180116.1 hypothetical protein -
CFSAN002064_RS00175 32545..32874 + 330 WP_000866646.1 hypothetical protein -
CFSAN002064_RS23425 32917..33096 + 180 WP_000439078.1 hypothetical protein -
CFSAN002064_RS25210 33118..33315 + 198 WP_001675595.1 hypothetical protein -
CFSAN002064_RS23430 33328..33600 + 273 WP_000160399.1 hypothetical protein -
CFSAN002064_RS25655 33857..33931 + 75 Protein_38 DNA distortion polypeptide 3 -
CFSAN002064_RS00185 33926..34471 + 546 WP_000757693.1 hypothetical protein -
CFSAN002064_RS00190 34474..35640 + 1167 WP_000539532.1 relaxase/mobilization nuclease domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..37692 37692


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(17-116)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 12066.38 Da        Isoelectric Point: 12.7685

>T45153 WP_000220560.1 NZ_CP005994:31207-31488 [Salmonella enterica subsp. enterica serovar Heidelberg str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Download         Length: 282 bp

>T45153 NZ_CP005994:31207-31488 [Salmonella enterica subsp. enterica serovar Heidelberg str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 10784.64 Da        Isoelectric Point: 12.7191

>AT45153 WP_000121743.1 NZ_CP005994:30966-31217 [Salmonella enterica subsp. enterica serovar Heidelberg str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Download         Length: 252 bp

>AT45153 NZ_CP005994:30966-31217 [Salmonella enterica subsp. enterica serovar Heidelberg str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB G3CAN5

Antitoxin

Source ID Structure
AlphaFold DB A0A3S5I301

References