45142

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 4544762..4545287 Replicon chromosome
Accession NZ_CP005969
Organism Pseudomonas syringae pv. syringae B301D

Toxin (Protein)


Gene name stbE Uniprot ID Q4ZPQ9
Locus tag PSYRB_RS27610 Protein ID WP_011268681.1
Coordinates 4544997..4545287 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q4ZPR0
Locus tag PSYRB_RS19450 Protein ID WP_003402372.1
Coordinates 4544762..4545007 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSYRB_RS19445 4540677..4544588 - 3912 WP_024640258.1 ATP-dependent RNA helicase HrpA -
PSYRB_RS19450 4544762..4545007 + 246 WP_003402372.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PSYRB_RS27610 4544997..4545287 + 291 WP_011268681.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSYRB_RS19460 4545605..4547296 - 1692 WP_032656728.1 long-chain-fatty-acid--CoA ligase FadD1 -
PSYRB_RS19465 4547652..4549340 - 1689 WP_024640260.1 long-chain-fatty-acid--CoA ligase FadD2 -
PSYRB_RS19470 4549709..4550179 + 471 WP_003402365.1 MaoC family dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11010.01 Da        Isoelectric Point: 10.7294

>T45142 WP_011268681.1 NZ_CP005969:4544997-4545287 [Pseudomonas syringae pv. syringae B301D]
MTFKLEFLPSALKEWEKLGHTIRVQLKKKLLERLGLPRIPGDALHGMPDHYKIKLRSAGYRLVYRVEEDRVVVTVVAVGK
RERGNIYDSAKGRLGP

Download         Length: 291 bp

>T45142 NZ_CP005969:4544997-4545287 [Pseudomonas syringae pv. syringae B301D]
ATGACCTTTAAGCTTGAATTTCTGCCCTCGGCCTTGAAGGAGTGGGAAAAACTGGGCCATACCATCCGTGTTCAGCTCAA
GAAAAAGCTTCTCGAACGACTCGGACTACCAAGAATTCCAGGCGATGCGCTTCATGGCATGCCAGATCATTACAAAATCA
AACTGCGCAGTGCAGGATACCGACTCGTCTATCGAGTCGAGGAAGATAGGGTAGTGGTAACCGTCGTTGCGGTAGGCAAG
CGCGAGCGCGGGAATATTTATGATTCGGCCAAAGGCAGGCTTGGCCCTTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8827.22 Da        Isoelectric Point: 4.5349

>AT45142 WP_003402372.1 NZ_CP005969:4544762-4545007 [Pseudomonas syringae pv. syringae B301D]
MQSILADVAVSVSELKKNPSAVLSGAHGLPVAVLNHNKVMGYMVPAEVFEAMMERLDDLDLAELIKSRQHEKPVSVDIDD
L

Download         Length: 246 bp

>AT45142 NZ_CP005969:4544762-4545007 [Pseudomonas syringae pv. syringae B301D]
ATGCAAAGCATCCTTGCAGATGTCGCGGTCAGCGTCTCTGAACTCAAGAAAAATCCGTCAGCGGTCCTGAGTGGCGCTCA
TGGTTTACCTGTGGCCGTCCTTAATCACAATAAAGTCATGGGCTACATGGTCCCTGCCGAGGTGTTTGAAGCAATGATGG
AGAGGCTTGATGACCTTGATCTGGCCGAGCTGATCAAATCTCGCCAACATGAAAAGCCGGTGTCGGTAGATATAGATGAC
CTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q4ZPQ9

Antitoxin

Source ID Structure
AlphaFold DB A0A3M2V2W1

References