Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 5103492..5103997 Replicon chromosome
Accession NZ_CP005960
Organism Pseudomonas mandelii JR-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OU5_RS22865 Protein ID WP_010458025.1
Coordinates 5103492..5103746 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OU5_RS22870 Protein ID WP_010458023.1
Coordinates 5103743..5103997 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OU5_RS22840 5099094..5099801 + 708 WP_010458035.1 peptide-methionine (S)-S-oxide reductase MsrA -
OU5_RS22845 5099814..5100218 - 405 WP_010458034.1 GNAT family N-acetyltransferase -
OU5_RS22850 5100215..5101228 - 1014 WP_010458032.1 sensor domain-containing diguanylate cyclase -
OU5_RS22855 5101300..5102205 - 906 WP_010458031.1 LysR family transcriptional regulator -
OU5_RS22860 5102308..5103483 + 1176 WP_010458027.1 aspartate aminotransferase family protein -
OU5_RS22865 5103492..5103746 - 255 WP_010458025.1 Txe/YoeB family addiction module toxin Toxin
OU5_RS22870 5103743..5103997 - 255 WP_010458023.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OU5_RS22875 5104150..5104605 - 456 WP_010458021.1 VOC family protein -
OU5_RS22880 5104618..5105127 - 510 WP_010458019.1 adenylate kinase -
OU5_RS22885 5105142..5107058 - 1917 WP_010458018.1 alkaline phosphatase family protein -
OU5_RS22890 5107179..5107541 - 363 WP_010458015.1 hypothetical protein -
OU5_RS22895 5107647..5107910 - 264 WP_010458013.1 hypothetical protein -
OU5_RS22900 5107900..5108691 - 792 WP_010458011.1 VacJ family lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9953.31 Da        Isoelectric Point: 5.6023

>T45139 WP_010458025.1 NZ_CP005960:c5103746-5103492 [Pseudomonas mandelii JR-1]
MNIEFTPEGWDDYLWFQQNDKAGLKRINLLITAIQGEPFDGLGKPEPLKHNLSGFWSRRITAEHRLVYEVDEGEIRVVMC
RYHY

Download         Length: 255 bp

>T45139 NZ_CP005960:c5103746-5103492 [Pseudomonas mandelii JR-1]
ATGAATATTGAGTTCACTCCCGAAGGTTGGGACGACTATTTATGGTTCCAACAAAATGACAAGGCCGGACTCAAACGAAT
CAACCTGCTCATCACAGCTATCCAGGGTGAACCATTCGACGGGCTCGGAAAGCCTGAGCCGCTCAAACACAATTTGAGCG
GCTTTTGGTCACGTCGAATTACTGCTGAGCATCGTTTGGTCTACGAGGTCGATGAAGGTGAGATTCGCGTCGTGATGTGT
AGATATCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9518.87 Da        Isoelectric Point: 7.0118

>AT45139 WP_010458023.1 NZ_CP005960:c5103997-5103743 [Pseudomonas mandelii JR-1]
MQTINYTTARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSISNLRAGKTQSRQ
LIEE

Download         Length: 255 bp

>AT45139 NZ_CP005960:c5103997-5103743 [Pseudomonas mandelii JR-1]
ATGCAAACTATCAACTACACCACCGCACGGGCCCATCTGGCCGAAACCATGGATAGGGTCAATGAAGACCGTGCGCCGTT
GCTGGTTACTCGCCAGAAAGGCGAACCCGTAGTGATGATGTCTCTGGCGGAGTACAACGCTCTCGAAGAGACCGCCTATC
TGCTGCGCTCCCCCGCCAATGCTGAGCGCCTGATCAAATCGATCAGCAACTTGCGTGCAGGGAAGACCCAATCCAGGCAA
CTCATCGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References