Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1877704..1878373 Replicon chromosome
Accession NZ_CP005927
Organism Serratia sp. FS14

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag L085_RS08480 Protein ID WP_004931681.1
Coordinates 1877951..1878373 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag L085_RS08475 Protein ID WP_004931679.1
Coordinates 1877704..1877970 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L085_RS08450 1873271..1874197 + 927 WP_021505706.1 ribokinase -
L085_RS08455 1874238..1874846 - 609 WP_004931670.1 HD domain-containing protein -
L085_RS08460 1875030..1875704 + 675 WP_021505704.1 hemolysin III family protein -
L085_RS08465 1875855..1876352 + 498 WP_044030541.1 DUF2165 domain-containing protein -
L085_RS08470 1876391..1877383 - 993 WP_044030542.1 tRNA-modifying protein YgfZ -
L085_RS08475 1877704..1877970 + 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
L085_RS08480 1877951..1878373 + 423 WP_004931681.1 protein YgfX Toxin
L085_RS08485 1878439..1878957 - 519 WP_044030543.1 flavodoxin FldB -
L085_RS08490 1879064..1879963 + 900 WP_004931685.1 site-specific tyrosine recombinase XerD -
L085_RS08495 1879990..1880706 + 717 WP_004931688.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
L085_RS08500 1880713..1882446 + 1734 WP_015378966.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1809279..1881675 72396


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16487.59 Da        Isoelectric Point: 11.0198

>T45087 WP_004931681.1 NZ_CP005927:1877951-1878373 [Serratia sp. FS14]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGDGEQG

Download         Length: 423 bp

>T45087 NZ_CP005927:1877951-1878373 [Serratia sp. FS14]
GTGGCCCAGTGGCGATGTGATATCCGCATTTCCTGGCGCACCCAGCTGTTTTCACTGTTAACCCACGGTGTTCTGATCCT
GCTGATCCTGATTTCGCCCTGGCCGGAAGGCTTTGGCCCACTCTGGCTGGTGCTGCTGACGCTGGTGGTGTTTCAGTGCA
TTCGCAGCCAGAAGCGCATCGCCGCGGTGCAGGGCGAGCTGCGGCTGCTGGCGGATCGGCGTTTCAGCTGGCACGGCCGC
GAGTGGCGACTGGCGAAAAAACCGTGGATGCCGGGTTACGGCATGCTGTTGACGCTACAGCCTATGGAGGGCAAAAAGCG
CCGCCGGCTGTGGCTGGCTTCCGACTGCATGAGCAAAGAGGAATGGCGCCACCTGCGGCAGCTGTTGCTGTATCCGCCGG
CGGGTGACGGCGAACAAGGTTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT45087 WP_004931679.1 NZ_CP005927:1877704-1877970 [Serratia sp. FS14]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT45087 NZ_CP005927:1877704-1877970 [Serratia sp. FS14]
ATGGATATTAACAACAAAGCACGTATTCACTGGGCTTGCCGCCGTGGCATGCGCGAGCTGGACATCTCCATCATGCCGTT
CTTCGAATACGAATACGACAGCCTGAATGACGCGGACAAGGCGCTGTTTATCCGCCTGCTGGAGTGCGACGATCCCGATT
TGTTCAACTGGCTGATGAATCATGGCGCGCCGCAGGACGGCGAGCTGCAAAGAATGGTGACCCTGATCCAAACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References