Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1083935..1084702 Replicon chromosome
Accession NZ_CP005927
Organism Serratia sp. FS14

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag L085_RS05000 Protein ID WP_025160422.1
Coordinates 1084334..1084702 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag L085_RS04995 Protein ID WP_044030218.1
Coordinates 1083935..1084270 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L085_RS04970 1080043..1080849 + 807 WP_044030214.1 hypothetical protein -
L085_RS04975 1081058..1081813 + 756 WP_044031930.1 50S ribosome-binding GTPase -
L085_RS04980 1082061..1082615 + 555 WP_044030216.1 hypothetical protein -
L085_RS04985 1082643..1083263 + 621 WP_044031931.1 hypothetical protein -
L085_RS24375 1083446..1083925 + 480 WP_071841599.1 DNA repair protein RadC -
L085_RS04995 1083935..1084270 + 336 WP_044030218.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
L085_RS05000 1084334..1084702 + 369 WP_025160422.1 TA system toxin CbtA family protein Toxin
L085_RS05005 1084932..1085786 + 855 WP_044031932.1 DUF4942 domain-containing protein -
L085_RS05010 1086135..1086473 - 339 WP_044030221.1 hypothetical protein -
L085_RS05015 1086673..1087575 - 903 WP_044030222.1 LysR family transcriptional regulator -
L085_RS05020 1087716..1089251 + 1536 WP_044030224.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13713.73 Da        Isoelectric Point: 5.5998

>T45085 WP_025160422.1 NZ_CP005927:1084334-1084702 [Serratia sp. FS14]
MQILPVTPKQAAYACPSPVIVWQSMLTYLLEQHYGLALNDTEFSDDAVIHEHIDAGISLADALNFTVEKFDLVRIDRRGF
SCQEQSPFITAIDILRARRATGLMTRLGYQTITSVIRGEKQT

Download         Length: 369 bp

>T45085 NZ_CP005927:1084334-1084702 [Serratia sp. FS14]
ATGCAAATCTTACCTGTCACTCCGAAACAGGCGGCTTACGCTTGCCCATCACCCGTTATTGTCTGGCAATCCATGCTCAC
GTATCTGCTGGAACAGCATTACGGATTGGCGCTTAACGATACCGAGTTCAGTGATGACGCGGTGATCCACGAACATATTG
ATGCCGGTATCTCTCTGGCTGATGCGTTGAATTTCACGGTGGAAAAGTTCGACCTGGTTCGCATCGATCGCCGGGGGTTC
TCCTGCCAGGAACAATCTCCCTTCATCACGGCTATCGATATTCTCCGTGCCCGTCGAGCCACCGGCCTGATGACCCGTCT
GGGTTACCAGACCATCACCTCAGTTATCCGGGGCGAAAAGCAGACATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12388.06 Da        Isoelectric Point: 6.0536

>AT45085 WP_044030218.1 NZ_CP005927:1083935-1084270 [Serratia sp. FS14]
MPPIIAPAWGLKRNVTPQLGARLVQEGDRLHFLIDRADISGTFSDAQLRDVDNTFPQFINHLELMLLSGELNPRYQHCVT
LYRNGLTCEADSLGSHGYVYLSIYPTPSSTA

Download         Length: 336 bp

>AT45085 NZ_CP005927:1083935-1084270 [Serratia sp. FS14]
ATGCCACCAATCATTGCCCCGGCCTGGGGACTCAAACGCAACGTCACTCCGCAGTTGGGTGCCCGCCTGGTACAGGAAGG
TGACCGGCTGCATTTTCTGATCGACCGTGCCGATATCAGCGGGACCTTCAGCGACGCGCAGCTACGAGATGTAGATAACA
CTTTCCCGCAGTTCATCAACCACCTGGAACTGATGCTGCTTTCTGGTGAACTCAATCCCCGCTATCAGCACTGCGTCACG
CTTTACCGCAATGGACTAACCTGTGAAGCCGATAGCCTGGGATCACACGGCTATGTGTATCTCTCCATTTATCCTACGCC
TTCATCAACGGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References