Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 245308..245840 Replicon chromosome
Accession NZ_CP004387
Organism Alcanivorax pacificus W11-5

Toxin (Protein)


Gene name parE Uniprot ID A0A0B4XF55
Locus tag S7S_RS01175 Protein ID WP_008736164.1
Coordinates 245308..245601 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A0B4XIZ0
Locus tag S7S_RS01180 Protein ID WP_008736166.1
Coordinates 245601..245840 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
S7S_RS01140 240723..241148 - 426 WP_008736149.1 OsmC family protein -
S7S_RS01145 241234..241911 - 678 WP_008736152.1 hypothetical protein -
S7S_RS01150 241976..242497 - 522 WP_008736154.1 hypothetical protein -
S7S_RS01155 242632..242832 + 201 WP_008736156.1 hemin uptake protein HemP -
S7S_RS01160 243061..244053 + 993 WP_169745541.1 hypothetical protein -
S7S_RS01165 244064..244387 - 324 WP_008736160.1 YqcC family protein -
S7S_RS01170 244380..245087 - 708 WP_008736162.1 HAD family hydrolase -
S7S_RS01175 245308..245601 - 294 WP_008736164.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
S7S_RS01180 245601..245840 - 240 WP_008736166.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
S7S_RS01185 246083..246877 + 795 WP_035204391.1 AadA family aminoglycoside 3''-O-nucleotidyltransferase -
S7S_RS01190 246957..247373 + 417 WP_008736170.1 MAPEG family protein -
S7S_RS01195 247595..248242 + 648 WP_008736171.1 carbonate dehydratase -
S7S_RS19035 248686..249360 + 675 WP_082027595.1 amino acid racemase -
S7S_RS01205 249601..250551 + 951 WP_008736176.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11281.06 Da        Isoelectric Point: 10.4599

>T45025 WP_008736164.1 NZ_CP004387:c245601-245308 [Alcanivorax pacificus W11-5]
MPPFLLTAAARKDVIDIGRFTAEKWGKRQRDKYLKQLDDTFRLLARQPEIGRDAEDIKPGYKKFSQGSHIVFYRPGTDAK
IVVIRILHNSMDVDRHI

Download         Length: 294 bp

>T45025 NZ_CP004387:c245601-245308 [Alcanivorax pacificus W11-5]
ATGCCTCCGTTCCTGCTCACCGCCGCCGCCCGAAAGGACGTCATTGATATTGGCCGCTTTACTGCTGAGAAGTGGGGGAA
ACGGCAACGCGACAAGTACCTCAAGCAGCTTGATGACACCTTCAGGCTGCTTGCCCGCCAGCCTGAAATAGGCCGCGATG
CAGAAGATATAAAGCCCGGGTACAAGAAGTTTAGTCAAGGCAGTCACATTGTCTTCTACCGGCCAGGCACGGATGCCAAA
ATTGTGGTGATTCGCATTCTTCACAACAGCATGGATGTGGATCGACATATCTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8874.76 Da        Isoelectric Point: 4.3803

>AT45025 WP_008736166.1 NZ_CP004387:c245840-245601 [Alcanivorax pacificus W11-5]
MARNTSITLGPHFDEFISTQVENGRYSSASEVVRAGLRLLEETESKLTRLRRLLDEGEQSGIAEYSYESIIAELDSEAH

Download         Length: 240 bp

>AT45025 NZ_CP004387:c245840-245601 [Alcanivorax pacificus W11-5]
ATGGCCAGAAACACCAGCATTACGCTTGGCCCCCATTTTGATGAATTCATATCCACGCAGGTGGAGAATGGCCGCTACAG
TTCCGCCAGCGAAGTGGTACGCGCCGGGTTGCGCCTGCTTGAGGAAACGGAAAGCAAGCTTACCCGTCTGCGGCGTCTTT
TAGACGAGGGCGAGCAAAGTGGTATAGCAGAGTACTCCTACGAAAGCATTATTGCGGAACTGGACAGCGAGGCTCACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B4XF55

Antitoxin

Source ID Structure
AlphaFold DB A0A0B4XIZ0

References