Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1926337..1926571 Replicon chromosome
Accession NZ_CP004057
Organism Shigella flexneri Shi06HN006 isolate Human

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1926338..1926441 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1926337..1926571 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SFYV_RS10640 1921769..1922236 - 468 Protein_1933 DNA-binding transcriptional regulator PgrR -
SFYV_RS10645 1922300..1922610 + 311 Protein_1934 transposase -
SFYV_RS26455 1922653..1923862 - 1210 Protein_1935 IS3 family transposase -
SFYV_RS10665 1923917..1924765 + 849 Protein_1936 IS3-like element IS600 family transposase -
SFYV_RS26460 1924882..1925163 + 282 WP_005127484.1 excisionase -
SFYV_RS29340 1925129..1926206 + 1078 Protein_1938 phage integrase Arm DNA-binding domain-containing protein -
- 1926337..1926571 + 235 - - Antitoxin
- 1926338..1926441 - 104 - - Toxin
SFYV_RS10680 1926599..1926940 - 342 WP_000976476.1 YebY family protein -
SFYV_RS26475 1926953..1927825 - 873 Protein_1940 copper homeostasis membrane protein CopD -
SFYV_RS10695 1927829..1928203 - 375 WP_000168747.1 CopC domain-containing protein YobA -
SFYV_RS10700 1928342..1928572 + 231 WP_000916763.1 DNA polymerase III subunit theta -
SFYV_RS10705 1928674..1929330 + 657 Protein_1943 carbon-nitrogen hydrolase family protein -
SFYV_RS10710 1929354..1930016 + 663 WP_000944268.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T44941 NZ_CP004057:c1926441-1926338 [Shigella flexneri Shi06HN006]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT44941 NZ_CP004057:1926337-1926571 [Shigella flexneri Shi06HN006]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References