Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1906329..1906563 | Replicon | chromosome |
| Accession | NZ_CP004056 | ||
| Organism | Shigella flexneri 2003036 isolate Human | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1906330..1906433 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1906329..1906563 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SFY_RS10435 | 1901761..1902228 | - | 468 | Protein_1900 | DNA-binding transcriptional regulator PgrR | - |
| SFY_RS10440 | 1902292..1902602 | + | 311 | Protein_1901 | transposase | - |
| SFY_RS25990 | 1902645..1903854 | - | 1210 | Protein_1902 | IS3 family transposase | - |
| SFY_RS10460 | 1903909..1904757 | + | 849 | Protein_1903 | IS3-like element IS600 family transposase | - |
| SFY_RS25995 | 1904874..1905155 | + | 282 | WP_005127484.1 | excisionase | - |
| SFY_RS26000 | 1905121..1905513 | + | 393 | WP_001189099.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| SFY_RS26005 | 1905832..1906198 | + | 367 | Protein_1906 | tyrosine-type recombinase/integrase | - |
| - | 1906329..1906563 | + | 235 | - | - | Antitoxin |
| - | 1906330..1906433 | - | 104 | - | - | Toxin |
| SFY_RS10475 | 1906591..1906932 | - | 342 | WP_000976476.1 | YebY family protein | - |
| SFY_RS26010 | 1906945..1907817 | - | 873 | Protein_1908 | copper homeostasis membrane protein CopD | - |
| SFY_RS10490 | 1907821..1908195 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| SFY_RS10495 | 1908334..1908564 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| SFY_RS10500 | 1908666..1909322 | + | 657 | Protein_1911 | carbon-nitrogen hydrolase family protein | - |
| SFY_RS10505 | 1909346..1910008 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T44920 NZ_CP004056:c1906433-1906330 [Shigella flexneri 2003036]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT44920 NZ_CP004056:1906329-1906563 [Shigella flexneri 2003036]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
