Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1967517..1967662 Replicon chromosome
Accession NZ_CP003999
Organism Klebsiella pneumoniae subsp. pneumoniae Kp13

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1967553..1967655 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1967517..1967662 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP13_RS10470 1962647..1964707 + 2061 WP_004151449.1 oligopeptidase B -
KP13_RS10475 1964711..1965370 - 660 WP_002911407.1 exodeoxyribonuclease X -
KP13_RS10480 1965449..1965679 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KP13_RS10485 1965792..1966166 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KP13_RS10490 1966170..1967039 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KP13_RS10495 1967056..1967394 + 339 WP_002911404.1 YebY family protein -
- 1967517..1967662 - 146 - - Antitoxin
- 1967553..1967655 + 103 - - Toxin
KP13_RS30920 1968030..1968173 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KP13_RS10505 1968278..1969246 - 969 WP_004151446.1 VirK/YbjX family protein -
KP13_RS10510 1969403..1970056 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
KP13_RS10515 1970053..1970244 - 192 WP_002911395.1 YebW family protein -
KP13_RS10520 1970342..1970581 - 240 WP_002911393.1 YebV family protein -
KP13_RS10525 1970697..1972130 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T44879 NZ_CP003999:1967553-1967655 [Klebsiella pneumoniae subsp. pneumoniae Kp13]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT44879 NZ_CP003999:c1967662-1967517 [Klebsiella pneumoniae subsp. pneumoniae Kp13]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References