Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 880594..881204 Replicon chromosome
Accession NZ_CP003915
Organism Advenella mimigardefordensis DPN7

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag MIM_RS04050 Protein ID WP_025371485.1
Coordinates 880594..880890 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MIM_RS04055 Protein ID WP_025371486.1
Coordinates 880896..881204 (+) Length 103 a.a.

Genomic Context

MIM_RS04025MIM_RS04035MIM_RS04040MIM_RS04045MIM_RS04050MIM_RS04055MIM_RS04060MIM_RS04065MIM_RS04070MIM_RS04030MIM_RS04075
Location: 876317..877642 (1326 bp)
Type: Others
Protein ID: WP_025371480.1
Location: 878482..879108 (627 bp)
Type: Others
Protein ID: WP_025371482.1
Location: 879198..879437 (240 bp)
Type: Others
Protein ID: WP_025371483.1
Location: 880006..880497 (492 bp)
Type: Others
Protein ID: WP_187329599.1
Location: 880594..880890 (297 bp)
Type: Toxin
Protein ID: WP_025371485.1
Location: 880896..881204 (309 bp)
Type: Antitoxin
Protein ID: WP_025371486.1
Location: 881805..882104 (300 bp)
Type: Others
Protein ID: WP_025371487.1
Location: 882091..882377 (287 bp)
Type: Others
Protein ID: Protein_810
Location: 882806..884647 (1842 bp)
Type: Others
Protein ID: WP_025371488.1
Location: 877763..878278 (516 bp)
Type: Others
Protein ID: WP_025371481.1
Location: 884848..885765 (918 bp)
Type: Others
Protein ID: WP_025371489.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MIM_RS04025876317..877642+1326WP_025371480.1hypothetical protein-
MIM_RS04030877763..878278-516WP_025371481.1thermonuclease family protein-
MIM_RS04035878482..879108+627WP_025371482.1hypothetical protein-
MIM_RS04040879198..879437+240WP_025371483.1hypothetical protein-
MIM_RS04045880006..880497+492WP_187329599.1JAB domain-containing protein-
MIM_RS04050880594..880890+297WP_025371485.1type II toxin-antitoxin system RelE/ParE family toxinToxin
MIM_RS04055880896..881204+309WP_025371486.1putative addiction module antidote proteinAntitoxin
MIM_RS04060881805..882104+300WP_025371487.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
MIM_RS04065882091..882377+287Protein_810type II toxin-antitoxin system RelE/ParE family toxin-
MIM_RS04070882806..884647+1842WP_025371488.1ABC transporter ATP-binding protein/permease-
MIM_RS04075884848..885765-918WP_025371489.1dihydrodipicolinate synthase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--865220..88210416884


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-91)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11143.92 Da        Isoelectric Point: 10.6937

>T44868 WP_025371485.1 NZ_CP003915:880594-880890 [Advenella mimigardefordensis DPN7]
MIEVIKSDVFDRWLNSLKDRQARARVQTRIRRLSLGNPGDVKPVGGGVSEMRIDYGPGYRLYYMQRGPVVVVLLCGGDKR
TQSRDIAHAKVIATQWKE

Download         Length: 297 bp

>T44868 NZ_CP003915:880594-880890 [Advenella mimigardefordensis DPN7]
ATGATCGAAGTTATTAAATCCGATGTTTTCGACCGCTGGCTTAACTCGCTGAAGGATCGCCAAGCACGGGCAAGGGTACA
AACCCGCATTCGGCGGCTCAGCCTGGGTAATCCTGGCGATGTTAAGCCAGTCGGTGGGGGTGTTTCCGAGATGAGAATCG
ATTATGGCCCTGGGTATCGCCTATATTACATGCAGCGCGGTCCGGTGGTTGTGGTGTTGCTCTGTGGCGGCGACAAGCGT
ACTCAAAGCCGTGACATTGCCCACGCAAAGGTAATAGCCACACAATGGAAGGAGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10852.22 Da        Isoelectric Point: 4.5895

>AT44868 WP_025371486.1 NZ_CP003915:880896-881204 [Advenella mimigardefordensis DPN7]
MDVKFSRYDTADYLKSEEDIVAYLDAVMEDGEPGLIAAALGDVARARNLSQLARDVGMSRQGLDKALSGEGNPSLATVLK
VAQALGLRLSWKVDNASHSTGV

Download         Length: 309 bp

>AT44868 NZ_CP003915:880896-881204 [Advenella mimigardefordensis DPN7]
ATGGACGTTAAATTTAGCCGCTACGACACGGCTGATTATCTCAAGAGCGAAGAAGATATCGTTGCCTACCTTGATGCCGT
AATGGAAGACGGAGAACCCGGCCTAATTGCGGCTGCGCTTGGTGATGTCGCACGAGCCAGAAATTTGAGTCAACTTGCGC
GTGATGTCGGTATGAGCCGTCAGGGGCTAGATAAGGCCCTTTCTGGCGAAGGCAATCCTAGCCTTGCGACAGTGTTAAAA
GTTGCTCAGGCACTTGGTTTACGCTTGTCGTGGAAAGTGGATAATGCCAGCCATTCCACTGGCGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References