Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 91634..92169 Replicon chromosome
Accession NZ_CP003424
Organism Serratia sp. SCBI

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SERRSCBI_RS00435 Protein ID WP_042783410.1
Coordinates 91894..92169 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8G2GBD7
Locus tag SERRSCBI_RS00430 Protein ID WP_033639076.1
Coordinates 91634..91894 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SERRSCBI_RS00410 86953..87603 + 651 WP_042783406.1 DcrB-related protein -
SERRSCBI_RS00415 87644..88249 + 606 WP_042783407.1 glutathione S-transferase -
SERRSCBI_RS00420 88319..89713 + 1395 WP_042783408.1 L-seryl-tRNA(Sec) selenium transferase -
SERRSCBI_RS00425 89710..91551 + 1842 WP_042783409.1 selenocysteine-specific translation elongation factor -
SERRSCBI_RS00430 91634..91894 + 261 WP_033639076.1 ribbon-helix-helix domain-containing protein Antitoxin
SERRSCBI_RS00435 91894..92169 + 276 WP_042783410.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SERRSCBI_RS00440 92350..93597 - 1248 WP_033633516.1 MFS transporter -
SERRSCBI_RS00445 93815..94807 + 993 WP_042783411.1 acyltransferase -
SERRSCBI_RS00450 94802..95725 - 924 WP_042783412.1 DJ-1/PfpI family protein -
SERRSCBI_RS00455 95728..96279 - 552 WP_033652293.1 isochorismatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10618.39 Da        Isoelectric Point: 10.3377

>T44842 WP_042783410.1 NZ_CP003424:91894-92169 [Serratia sp. SCBI]
MELKWTSKALPDLARLFEFLALANRTAAANSVKALVAAPKALLDNPRLSERLDEFLPQEVRRILVGRYEIRYQVQPATIY
VLRIWHTREER

Download         Length: 276 bp

>T44842 NZ_CP003424:91894-92169 [Serratia sp. SCBI]
ATGGAGTTAAAATGGACGAGTAAGGCGCTACCGGATTTGGCGCGTTTGTTTGAGTTTCTTGCCTTGGCTAACCGCACTGC
GGCAGCGAATTCGGTGAAGGCCTTGGTCGCCGCGCCTAAAGCGTTGCTCGATAATCCTCGCCTGAGTGAAAGACTGGACG
AGTTTTTACCGCAGGAAGTGAGGCGTATTCTGGTCGGCCGTTATGAGATACGTTACCAGGTGCAGCCGGCAACGATTTAT
GTTCTGCGTATTTGGCATACCCGCGAAGAGCGATAG

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9682.01 Da        Isoelectric Point: 4.5317

>AT44842 WP_033639076.1 NZ_CP003424:91634-91894 [Serratia sp. SCBI]
MNTKVITAHVPLPLAEKVDEMAAKLERSRGWIVKQALAAWLEQEEERRRLTLAALADVEQQNVIDHESVEAWAASLDSDE
PLPVPR

Download         Length: 261 bp

>AT44842 NZ_CP003424:91634-91894 [Serratia sp. SCBI]
ATGAATACGAAAGTCATCACCGCTCATGTCCCGCTGCCGTTGGCTGAAAAGGTGGATGAAATGGCCGCCAAACTTGAACG
CTCACGGGGATGGATAGTGAAGCAAGCCCTCGCCGCCTGGCTTGAGCAAGAGGAAGAGCGCCGTCGGTTAACGCTGGCGG
CGCTGGCCGATGTCGAACAGCAAAACGTTATCGATCATGAGTCGGTAGAAGCCTGGGCGGCCAGCCTGGACAGTGACGAG
CCGCTGCCGGTACCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References