Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 482352..483005 Replicon chromosome
Accession NZ_CP001172
Organism Acinetobacter baumannii AB307-0294

Toxin (Protein)


Gene name cptA Uniprot ID B0V6V2
Locus tag ABBFA_RS02370 Protein ID WP_000931890.1
Coordinates 482616..483005 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag ABBFA_RS02365 Protein ID WP_001288210.1
Coordinates 482352..482609 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABBFA_RS02345 477868..478875 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
ABBFA_RS02350 478894..479271 + 378 WP_001216380.1 50S ribosomal protein L17 -
ABBFA_RS02355 479452..480942 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
ABBFA_RS02360 480992..482164 - 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
ABBFA_RS02365 482352..482609 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
ABBFA_RS02370 482616..483005 + 390 WP_000931890.1 membrane protein Toxin
ABBFA_RS02375 483775..484860 + 1086 WP_000049106.1 hypothetical protein -
ABBFA_RS02380 484938..485504 + 567 WP_000651536.1 rhombosortase -
ABBFA_RS02385 485692..487887 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.98 Da        Isoelectric Point: 10.4623

>T44580 WP_000931890.1 NZ_CP001172:482616-483005 [Acinetobacter baumannii AB307-0294]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T44580 NZ_CP001172:482616-483005 [Acinetobacter baumannii AB307-0294]
TTGCTCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATAAGCTTTATTTTCTTTT
TAAAGCGTCCGCAACTTGCAAAAATTGCCTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT44580 WP_001288210.1 NZ_CP001172:482352-482609 [Acinetobacter baumannii AB307-0294]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT44580 NZ_CP001172:482352-482609 [Acinetobacter baumannii AB307-0294]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J1A4U0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References