Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 1292609..1293141 Replicon chromosome
Accession NZ_AP028142
Organism Polynucleobacter sp. HIN11

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QUE60_RS06730 Protein ID WP_286226488.1
Coordinates 1292609..1292932 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QUE60_RS06735 Protein ID WP_286226489.1
Coordinates 1292929..1293141 (-) Length 71 a.a.

Genomic Context

QUE60_RS06725QUE60_RS06730QUE60_RS06735QUE60_RS06740QUE60_RS06745
Location: 1288794..1292612 (3819 bp)
Type: Others
Protein ID: WP_286226487.1
Location: 1292609..1292932 (324 bp)
Type: Toxin
Protein ID: WP_286226488.1
Location: 1292929..1293141 (213 bp)
Type: Antitoxin
Protein ID: WP_286226489.1
Location: 1293226..1294065 (840 bp)
Type: Others
Protein ID: WP_286226490.1
Location: 1294073..1294882 (810 bp)
Type: Others
Protein ID: WP_286226491.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QUE60_RS06725 (PHIN11_12970)1288794..1292612+3819WP_286226487.1magnesium chelatase subunit H-
QUE60_RS06730 (PHIN11_12980)1292609..1292932-324WP_286226488.1type II toxin-antitoxin system PemK/MazF family toxinToxin
QUE60_RS06735 (PHIN11_12990)1292929..1293141-213WP_286226489.1antitoxin MazE family proteinAntitoxin
QUE60_RS06740 (PHIN11_13000)1293226..1294065-840WP_286226490.1aldo/keto reductase-
QUE60_RS06745 (PHIN11_13010)1294073..1294882-810WP_286226491.1peptidylprolyl isomerase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-104)

Antitoxin

Antitoxin MazE-like

(8-69)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11686.56 Da        Isoelectric Point: 8.6590

>T44578 WP_286226488.1 NZ_AP028142:c1292932-1292609 [Polynucleobacter sp. HIN11]
VRRGDFVKVVTPGSYGKPRPALIVQSDLFNQHPSVSVLPLSSELRNAPLFRVPIEPSSMNGLEKRSEVMVDKIQTIPVDK
IGGEIGRASDEEMLAINRALAIFLGFA

Download         Length: 324 bp

>T44578 NZ_AP028142:c1292932-1292609 [Polynucleobacter sp. HIN11]
GTGAGGCGAGGTGATTTTGTAAAGGTTGTCACACCGGGCTCCTATGGCAAACCAAGACCCGCATTAATCGTTCAATCGGA
TTTATTTAATCAGCATCCATCGGTATCTGTGCTGCCTTTATCAAGTGAACTACGAAACGCTCCTTTGTTTAGGGTACCAA
TTGAACCCTCCTCAATGAATGGTTTAGAGAAACGTTCAGAGGTGATGGTGGACAAAATTCAGACCATACCAGTAGACAAG
ATTGGCGGAGAAATTGGGCGTGCTTCGGATGAAGAAATGCTAGCGATTAATCGTGCGCTGGCAATATTTTTAGGGTTTGC
TTAA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8317.43 Da        Isoelectric Point: 8.0273

>AT44578 WP_286226489.1 NZ_AP028142:c1293141-1292929 [Polynucleobacter sp. HIN11]
MPVATNLRVQKHRAQLRAAGLRPIQIWVPDTRQSSFAEECRRQSQMLKNDPLESEINEWLDEVRDTKDWK

Download         Length: 213 bp

>AT44578 NZ_AP028142:c1293141-1292929 [Polynucleobacter sp. HIN11]
ATGCCAGTTGCCACTAACTTAAGAGTCCAAAAACACCGGGCGCAATTACGTGCGGCAGGGCTTCGTCCTATCCAAATCTG
GGTTCCAGATACACGCCAATCCTCTTTTGCAGAGGAGTGTCGCCGTCAGTCGCAAATGTTAAAAAATGATCCACTCGAAT
CTGAAATCAATGAGTGGCTTGATGAGGTTCGTGATACCAAGGATTGGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References