Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 1115768..1116348 Replicon chromosome
Accession NZ_AP028142
Organism Polynucleobacter sp. HIN11

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QUE60_RS05880 Protein ID WP_286226396.1
Coordinates 1115768..1116094 (-) Length 109 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QUE60_RS05885 Protein ID WP_286223176.1
Coordinates 1116094..1116348 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE60_RS05855 (PHIN11_11300) 1111188..1112063 - 876 WP_286226394.1 dihydropteroate synthase -
QUE60_RS05860 (PHIN11_11310) 1112066..1113952 - 1887 WP_108508702.1 ATP-dependent zinc metalloprotease FtsH -
QUE60_RS05865 (PHIN11_11320) 1114115..1114780 - 666 WP_286223172.1 RlmE family RNA methyltransferase -
QUE60_RS05870 (PHIN11_11330) 1114836..1115291 + 456 WP_286226395.1 YhbY family RNA-binding protein -
QUE60_RS05875 (PHIN11_11340) 1115259..1115759 - 501 WP_286224963.1 DUF4149 domain-containing protein -
QUE60_RS05880 (PHIN11_11350) 1115768..1116094 - 327 WP_286226396.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QUE60_RS05885 (PHIN11_11360) 1116094..1116348 - 255 WP_286223176.1 antitoxin Antitoxin
QUE60_RS05890 (PHIN11_11370) 1116413..1116895 - 483 WP_108508707.1 transcription elongation factor GreA -
QUE60_RS05895 (PHIN11_11380) 1116934..1120182 - 3249 WP_286226397.1 carbamoyl-phosphate synthase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-105)

Antitoxin

Antitoxin PemI-like

(1-84)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11440.41 Da        Isoelectric Point: 10.3155

>T44577 WP_286226396.1 NZ_AP028142:c1116094-1115768 [Polynucleobacter sp. HIN11]
MKRGDIYLVSLDPTAGHEQKGYRPVLVVSPAPFNQLTKTPIVVPISTGGQFARVAGFAVELVGAKTVGIARCDQPRTLDL
AARKAKRVETVSAAVIDEVLAKLATLVT

Download         Length: 327 bp

>T44577 NZ_AP028142:c1116094-1115768 [Polynucleobacter sp. HIN11]
ATGAAGCGAGGCGATATTTATTTGGTATCTCTTGATCCAACGGCTGGCCATGAGCAAAAAGGGTATCGACCAGTATTGGT
AGTGTCACCAGCACCGTTTAATCAATTAACCAAGACCCCAATCGTTGTACCGATCTCCACTGGAGGTCAGTTTGCGCGGG
TGGCAGGATTTGCAGTTGAGCTGGTTGGAGCTAAAACTGTTGGTATTGCACGCTGCGATCAACCTCGCACACTAGACCTC
GCGGCTCGCAAAGCAAAACGCGTTGAGACCGTGTCGGCGGCTGTGATTGATGAGGTCTTGGCTAAACTAGCAACCTTAGT
TACCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9218.82 Da        Isoelectric Point: 7.8297

>AT44577 WP_286223176.1 NZ_AP028142:c1116348-1116094 [Polynucleobacter sp. HIN11]
MHTNLRKVGGSVMLAVSPVFLKELQITCGSTVDVALKDGQLVVRPIAKRKYELADLLAQCDPKAKMPSEDRQWLDSAPIG
NEIL

Download         Length: 255 bp

>AT44577 NZ_AP028142:c1116348-1116094 [Polynucleobacter sp. HIN11]
ATGCATACCAATTTAAGAAAGGTTGGAGGCTCAGTGATGCTGGCAGTGTCCCCGGTTTTCCTGAAAGAACTTCAGATCAC
TTGCGGATCGACCGTTGATGTCGCCCTAAAGGACGGGCAATTGGTCGTTCGACCCATCGCAAAGCGGAAGTACGAACTCG
CTGATTTATTAGCGCAATGCGATCCCAAAGCAAAAATGCCAAGCGAGGATCGGCAGTGGTTGGATAGCGCCCCGATCGGC
AATGAGATTCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References