Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 1293120..1293652 Replicon chromosome
Accession NZ_AP028141
Organism Polynucleobacter sp. HIN10

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QUE67_RS06745 Protein ID WP_286226488.1
Coordinates 1293120..1293443 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QUE67_RS06750 Protein ID WP_286226489.1
Coordinates 1293440..1293652 (-) Length 71 a.a.

Genomic Context

QUE67_RS06740QUE67_RS06745QUE67_RS06750QUE67_RS06755QUE67_RS06760
Location: 1289305..1293123 (3819 bp)
Type: Others
Protein ID: WP_286226487.1
Location: 1293120..1293443 (324 bp)
Type: Toxin
Protein ID: WP_286226488.1
Location: 1293440..1293652 (213 bp)
Type: Antitoxin
Protein ID: WP_286226489.1
Location: 1293737..1294576 (840 bp)
Type: Others
Protein ID: WP_286226490.1
Location: 1294584..1295393 (810 bp)
Type: Others
Protein ID: WP_286226491.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QUE67_RS06740 (PHIN10_12970)1289305..1293123+3819WP_286226487.1magnesium chelatase subunit H-
QUE67_RS06745 (PHIN10_12980)1293120..1293443-324WP_286226488.1type II toxin-antitoxin system PemK/MazF family toxinToxin
QUE67_RS06750 (PHIN10_12990)1293440..1293652-213WP_286226489.1antitoxin MazE family proteinAntitoxin
QUE67_RS06755 (PHIN10_13000)1293737..1294576-840WP_286226490.1aldo/keto reductase-
QUE67_RS06760 (PHIN10_13010)1294584..1295393-810WP_286226491.1peptidylprolyl isomerase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-104)

Antitoxin

Antitoxin MazE-like

(8-69)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11686.56 Da        Isoelectric Point: 8.6590

>T44575 WP_286226488.1 NZ_AP028141:c1293443-1293120 [Polynucleobacter sp. HIN10]
VRRGDFVKVVTPGSYGKPRPALIVQSDLFNQHPSVSVLPLSSELRNAPLFRVPIEPSSMNGLEKRSEVMVDKIQTIPVDK
IGGEIGRASDEEMLAINRALAIFLGFA

Download         Length: 324 bp

>T44575 NZ_AP028141:c1293443-1293120 [Polynucleobacter sp. HIN10]
GTGAGGCGAGGTGATTTTGTAAAGGTTGTCACACCGGGCTCCTATGGCAAACCAAGACCCGCATTAATCGTTCAATCGGA
TTTATTTAATCAGCATCCATCGGTATCTGTGCTGCCTTTATCAAGTGAACTACGAAACGCTCCTTTGTTTAGGGTACCAA
TTGAACCCTCCTCAATGAATGGTTTAGAGAAACGTTCAGAGGTGATGGTGGACAAAATTCAGACCATACCAGTAGACAAG
ATTGGCGGAGAAATTGGGCGTGCTTCGGATGAAGAAATGCTAGCGATTAATCGTGCGCTGGCAATATTTTTAGGGTTTGC
TTAA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8317.43 Da        Isoelectric Point: 8.0273

>AT44575 WP_286226489.1 NZ_AP028141:c1293652-1293440 [Polynucleobacter sp. HIN10]
MPVATNLRVQKHRAQLRAAGLRPIQIWVPDTRQSSFAEECRRQSQMLKNDPLESEINEWLDEVRDTKDWK

Download         Length: 213 bp

>AT44575 NZ_AP028141:c1293652-1293440 [Polynucleobacter sp. HIN10]
ATGCCAGTTGCCACTAACTTAAGAGTCCAAAAACACCGGGCGCAATTACGTGCGGCAGGGCTTCGTCCTATCCAAATCTG
GGTTCCAGATACACGCCAATCCTCTTTTGCAGAGGAGTGTCGCCGTCAGTCGCAAATGTTAAAAAATGATCCACTCGAAT
CTGAAATCAATGAGTGGCTTGATGAGGTTCGTGATACCAAGGATTGGAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References