Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pemIK/PRK09812-ChpS |
| Location | 1116279..1116859 | Replicon | chromosome |
| Accession | NZ_AP028141 | ||
| Organism | Polynucleobacter sp. HIN10 | ||
Toxin (Protein)
| Gene name | pemK | Uniprot ID | - |
| Locus tag | QUE67_RS05895 | Protein ID | WP_286226396.1 |
| Coordinates | 1116279..1116605 (-) | Length | 109 a.a. |
Antitoxin (Protein)
| Gene name | pemI | Uniprot ID | - |
| Locus tag | QUE67_RS05900 | Protein ID | WP_286223176.1 |
| Coordinates | 1116605..1116859 (-) | Length | 85 a.a. |
Genomic Context
Location: 1115347..1115802 (456 bp)
Type: Others
Protein ID: WP_286226395.1
Type: Others
Protein ID: WP_286226395.1
Location: 1111699..1112574 (876 bp)
Type: Others
Protein ID: WP_286226394.1
Type: Others
Protein ID: WP_286226394.1
Location: 1112577..1114463 (1887 bp)
Type: Others
Protein ID: WP_108508702.1
Type: Others
Protein ID: WP_108508702.1
Location: 1114626..1115291 (666 bp)
Type: Others
Protein ID: WP_286223172.1
Type: Others
Protein ID: WP_286223172.1
Location: 1115770..1116270 (501 bp)
Type: Others
Protein ID: WP_286224963.1
Type: Others
Protein ID: WP_286224963.1
Location: 1116279..1116605 (327 bp)
Type: Toxin
Protein ID: WP_286226396.1
Type: Toxin
Protein ID: WP_286226396.1
Location: 1116605..1116859 (255 bp)
Type: Antitoxin
Protein ID: WP_286223176.1
Type: Antitoxin
Protein ID: WP_286223176.1
Location: 1116924..1117406 (483 bp)
Type: Others
Protein ID: WP_108508707.1
Type: Others
Protein ID: WP_108508707.1
Location: 1117445..1120693 (3249 bp)
Type: Others
Protein ID: WP_286226397.1
Type: Others
Protein ID: WP_286226397.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUE67_RS05870 (PHIN10_11300) | 1111699..1112574 | - | 876 | WP_286226394.1 | dihydropteroate synthase | - |
| QUE67_RS05875 (PHIN10_11310) | 1112577..1114463 | - | 1887 | WP_108508702.1 | ATP-dependent zinc metalloprotease FtsH | - |
| QUE67_RS05880 (PHIN10_11320) | 1114626..1115291 | - | 666 | WP_286223172.1 | RlmE family RNA methyltransferase | - |
| QUE67_RS05885 (PHIN10_11330) | 1115347..1115802 | + | 456 | WP_286226395.1 | YhbY family RNA-binding protein | - |
| QUE67_RS05890 (PHIN10_11340) | 1115770..1116270 | - | 501 | WP_286224963.1 | DUF4149 domain-containing protein | - |
| QUE67_RS05895 (PHIN10_11350) | 1116279..1116605 | - | 327 | WP_286226396.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| QUE67_RS05900 (PHIN10_11360) | 1116605..1116859 | - | 255 | WP_286223176.1 | antitoxin | Antitoxin |
| QUE67_RS05905 (PHIN10_11370) | 1116924..1117406 | - | 483 | WP_108508707.1 | transcription elongation factor GreA | - |
| QUE67_RS05910 (PHIN10_11380) | 1117445..1120693 | - | 3249 | WP_286226397.1 | carbamoyl-phosphate synthase large subunit | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 109 a.a. Molecular weight: 11440.41 Da Isoelectric Point: 10.3155
>T44574 WP_286226396.1 NZ_AP028141:c1116605-1116279 [Polynucleobacter sp. HIN10]
MKRGDIYLVSLDPTAGHEQKGYRPVLVVSPAPFNQLTKTPIVVPISTGGQFARVAGFAVELVGAKTVGIARCDQPRTLDL
AARKAKRVETVSAAVIDEVLAKLATLVT
MKRGDIYLVSLDPTAGHEQKGYRPVLVVSPAPFNQLTKTPIVVPISTGGQFARVAGFAVELVGAKTVGIARCDQPRTLDL
AARKAKRVETVSAAVIDEVLAKLATLVT
Download Length: 327 bp
>T44574 NZ_AP028141:c1116605-1116279 [Polynucleobacter sp. HIN10]
ATGAAGCGAGGCGATATTTATTTGGTATCTCTTGATCCAACGGCTGGCCATGAGCAAAAAGGGTATCGACCAGTATTGGT
AGTGTCACCAGCACCGTTTAATCAATTAACCAAGACCCCAATCGTTGTACCGATCTCCACTGGAGGTCAGTTTGCGCGGG
TGGCAGGATTTGCAGTTGAGCTGGTTGGAGCTAAAACTGTTGGTATTGCACGCTGCGATCAACCTCGCACACTAGACCTC
GCGGCTCGCAAAGCAAAACGCGTTGAGACCGTGTCGGCGGCTGTGATTGATGAGGTCTTGGCTAAACTAGCAACCTTAGT
TACCTAG
ATGAAGCGAGGCGATATTTATTTGGTATCTCTTGATCCAACGGCTGGCCATGAGCAAAAAGGGTATCGACCAGTATTGGT
AGTGTCACCAGCACCGTTTAATCAATTAACCAAGACCCCAATCGTTGTACCGATCTCCACTGGAGGTCAGTTTGCGCGGG
TGGCAGGATTTGCAGTTGAGCTGGTTGGAGCTAAAACTGTTGGTATTGCACGCTGCGATCAACCTCGCACACTAGACCTC
GCGGCTCGCAAAGCAAAACGCGTTGAGACCGTGTCGGCGGCTGTGATTGATGAGGTCTTGGCTAAACTAGCAACCTTAGT
TACCTAG
Antitoxin
Download Length: 85 a.a. Molecular weight: 9218.82 Da Isoelectric Point: 7.8297
>AT44574 WP_286223176.1 NZ_AP028141:c1116859-1116605 [Polynucleobacter sp. HIN10]
MHTNLRKVGGSVMLAVSPVFLKELQITCGSTVDVALKDGQLVVRPIAKRKYELADLLAQCDPKAKMPSEDRQWLDSAPIG
NEIL
MHTNLRKVGGSVMLAVSPVFLKELQITCGSTVDVALKDGQLVVRPIAKRKYELADLLAQCDPKAKMPSEDRQWLDSAPIG
NEIL
Download Length: 255 bp
>AT44574 NZ_AP028141:c1116859-1116605 [Polynucleobacter sp. HIN10]
ATGCATACCAATTTAAGAAAGGTTGGAGGCTCAGTGATGCTGGCAGTGTCCCCGGTTTTCCTGAAAGAACTTCAGATCAC
TTGCGGATCGACCGTTGATGTCGCCCTAAAGGACGGGCAATTGGTCGTTCGACCCATCGCAAAGCGGAAGTACGAACTCG
CTGATTTATTAGCGCAATGCGATCCCAAAGCAAAAATGCCAAGCGAGGATCGGCAGTGGTTGGATAGCGCCCCGATCGGC
AATGAGATTCTGTAA
ATGCATACCAATTTAAGAAAGGTTGGAGGCTCAGTGATGCTGGCAGTGTCCCCGGTTTTCCTGAAAGAACTTCAGATCAC
TTGCGGATCGACCGTTGATGTCGCCCTAAAGGACGGGCAATTGGTCGTTCGACCCATCGCAAAGCGGAAGTACGAACTCG
CTGATTTATTAGCGCAATGCGATCCCAAAGCAAAAATGCCAAGCGAGGATCGGCAGTGGTTGGATAGCGCCCCGATCGGC
AATGAGATTCTGTAA