Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 1116279..1116859 Replicon chromosome
Accession NZ_AP028141
Organism Polynucleobacter sp. HIN10

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QUE67_RS05895 Protein ID WP_286226396.1
Coordinates 1116279..1116605 (-) Length 109 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QUE67_RS05900 Protein ID WP_286223176.1
Coordinates 1116605..1116859 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE67_RS05870 (PHIN10_11300) 1111699..1112574 - 876 WP_286226394.1 dihydropteroate synthase -
QUE67_RS05875 (PHIN10_11310) 1112577..1114463 - 1887 WP_108508702.1 ATP-dependent zinc metalloprotease FtsH -
QUE67_RS05880 (PHIN10_11320) 1114626..1115291 - 666 WP_286223172.1 RlmE family RNA methyltransferase -
QUE67_RS05885 (PHIN10_11330) 1115347..1115802 + 456 WP_286226395.1 YhbY family RNA-binding protein -
QUE67_RS05890 (PHIN10_11340) 1115770..1116270 - 501 WP_286224963.1 DUF4149 domain-containing protein -
QUE67_RS05895 (PHIN10_11350) 1116279..1116605 - 327 WP_286226396.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QUE67_RS05900 (PHIN10_11360) 1116605..1116859 - 255 WP_286223176.1 antitoxin Antitoxin
QUE67_RS05905 (PHIN10_11370) 1116924..1117406 - 483 WP_108508707.1 transcription elongation factor GreA -
QUE67_RS05910 (PHIN10_11380) 1117445..1120693 - 3249 WP_286226397.1 carbamoyl-phosphate synthase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-105)

Antitoxin

Antitoxin PemI-like

(1-84)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11440.41 Da        Isoelectric Point: 10.3155

>T44574 WP_286226396.1 NZ_AP028141:c1116605-1116279 [Polynucleobacter sp. HIN10]
MKRGDIYLVSLDPTAGHEQKGYRPVLVVSPAPFNQLTKTPIVVPISTGGQFARVAGFAVELVGAKTVGIARCDQPRTLDL
AARKAKRVETVSAAVIDEVLAKLATLVT

Download         Length: 327 bp

>T44574 NZ_AP028141:c1116605-1116279 [Polynucleobacter sp. HIN10]
ATGAAGCGAGGCGATATTTATTTGGTATCTCTTGATCCAACGGCTGGCCATGAGCAAAAAGGGTATCGACCAGTATTGGT
AGTGTCACCAGCACCGTTTAATCAATTAACCAAGACCCCAATCGTTGTACCGATCTCCACTGGAGGTCAGTTTGCGCGGG
TGGCAGGATTTGCAGTTGAGCTGGTTGGAGCTAAAACTGTTGGTATTGCACGCTGCGATCAACCTCGCACACTAGACCTC
GCGGCTCGCAAAGCAAAACGCGTTGAGACCGTGTCGGCGGCTGTGATTGATGAGGTCTTGGCTAAACTAGCAACCTTAGT
TACCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9218.82 Da        Isoelectric Point: 7.8297

>AT44574 WP_286223176.1 NZ_AP028141:c1116859-1116605 [Polynucleobacter sp. HIN10]
MHTNLRKVGGSVMLAVSPVFLKELQITCGSTVDVALKDGQLVVRPIAKRKYELADLLAQCDPKAKMPSEDRQWLDSAPIG
NEIL

Download         Length: 255 bp

>AT44574 NZ_AP028141:c1116859-1116605 [Polynucleobacter sp. HIN10]
ATGCATACCAATTTAAGAAAGGTTGGAGGCTCAGTGATGCTGGCAGTGTCCCCGGTTTTCCTGAAAGAACTTCAGATCAC
TTGCGGATCGACCGTTGATGTCGCCCTAAAGGACGGGCAATTGGTCGTTCGACCCATCGCAAAGCGGAAGTACGAACTCG
CTGATTTATTAGCGCAATGCGATCCCAAAGCAAAAATGCCAAGCGAGGATCGGCAGTGGTTGGATAGCGCCCCGATCGGC
AATGAGATTCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References