Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 1125118..1125698 Replicon chromosome
Accession NZ_AP028140
Organism Polynucleobacter sp. HIN9

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QUE62_RS05910 Protein ID WP_286223175.1
Coordinates 1125118..1125444 (-) Length 109 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QUE62_RS05915 Protein ID WP_286223176.1
Coordinates 1125444..1125698 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE62_RS05885 (PHIN9_11400) 1120538..1121413 - 876 WP_286261066.1 dihydropteroate synthase -
QUE62_RS05890 (PHIN9_11410) 1121416..1123302 - 1887 WP_108508702.1 ATP-dependent zinc metalloprotease FtsH -
QUE62_RS05895 (PHIN9_11420) 1123465..1124130 - 666 WP_286223172.1 RlmE family RNA methyltransferase -
QUE62_RS05900 (PHIN9_11430) 1124186..1124641 + 456 WP_286261068.1 YhbY family RNA-binding protein -
QUE62_RS05905 (PHIN9_11440) 1124609..1125109 - 501 WP_286224963.1 DUF4149 domain-containing protein -
QUE62_RS05910 (PHIN9_11450) 1125118..1125444 - 327 WP_286223175.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QUE62_RS05915 (PHIN9_11460) 1125444..1125698 - 255 WP_286223176.1 antitoxin Antitoxin
QUE62_RS05920 (PHIN9_11470) 1125763..1126245 - 483 WP_286224966.1 transcription elongation factor GreA -
QUE62_RS05925 (PHIN9_11480) 1126284..1129532 - 3249 WP_286261070.1 carbamoyl-phosphate synthase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-105)

Antitoxin

Antitoxin PemI-like

(1-84)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11528.47 Da        Isoelectric Point: 10.0519

>T44573 WP_286223175.1 NZ_AP028140:c1125444-1125118 [Polynucleobacter sp. HIN9]
MKRGDIYLVSLDPTAGHEQKGYRPVLVVSPAPFNQLTKTPIVVPISTGGQFARVAGFAVELVGAKTVGIARCDQPRTLDL
AARKAKRVETVSETVIDEVLAKLATLVT

Download         Length: 327 bp

>T44573 NZ_AP028140:c1125444-1125118 [Polynucleobacter sp. HIN9]
ATGAAGCGAGGCGATATTTATTTGGTATCTCTTGATCCAACGGCTGGCCATGAGCAAAAAGGGTATCGACCCGTATTGGT
AGTGTCACCAGCACCGTTTAATCAATTAACCAAGACCCCAATCGTTGTACCGATCTCCACTGGAGGTCAGTTTGCGCGGG
TGGCAGGATTTGCAGTTGAGCTGGTTGGAGCTAAAACTGTTGGTATTGCACGCTGCGATCAACCTCGCACACTAGACCTC
GCGGCTCGCAAAGCAAAACGCGTTGAGACCGTGTCGGAGACTGTGATTGATGAGGTCTTGGCTAAACTAGCAACCTTAGT
TACCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9218.82 Da        Isoelectric Point: 7.8297

>AT44573 WP_286223176.1 NZ_AP028140:c1125698-1125444 [Polynucleobacter sp. HIN9]
MHTNLRKVGGSVMLAVSPVFLKELQITCGSTVDVALKDGQLVVRPIAKRKYELADLLAQCDPKAKMPSEDRQWLDSAPIG
NEIL

Download         Length: 255 bp

>AT44573 NZ_AP028140:c1125698-1125444 [Polynucleobacter sp. HIN9]
ATGCATACCAATTTAAGAAAGGTTGGAGGCTCAGTGATGCTGGCAGTGTCCCCGGTTTTCCTTAAAGAACTTCAGATCAC
TTGCGGCTCGACCGTTGATGTCGCCCTAAAGGACGGGCAATTGGTCGTTCGACCCATCGCAAAGCGGAAGTACGAACTCG
CTGATTTATTAGCGCAATGCGATCCCAAAGCAAAAATGCCAAGCGAGGATCGGCAGTGGTTGGATAGCGCCCCGATCGGC
AATGAGATTCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References