Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 1128317..1128897 Replicon chromosome
Accession NZ_AP028138
Organism Polynucleobacter sp. HIN7

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QUE64_RS05955 Protein ID WP_286224964.1
Coordinates 1128317..1128643 (-) Length 109 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QUE64_RS05960 Protein ID WP_286224965.1
Coordinates 1128643..1128897 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE64_RS05930 (PHIN7_11470) 1123737..1124612 - 876 WP_286224961.1 dihydropteroate synthase -
QUE64_RS05935 (PHIN7_11480) 1124615..1126501 - 1887 WP_108508702.1 ATP-dependent zinc metalloprotease FtsH -
QUE64_RS05940 (PHIN7_11490) 1126664..1127329 - 666 WP_286223172.1 RlmE family RNA methyltransferase -
QUE64_RS05945 (PHIN7_11500) 1127385..1127840 + 456 WP_286224962.1 YhbY family RNA-binding protein -
QUE64_RS05950 (PHIN7_11510) 1127808..1128308 - 501 WP_286224963.1 DUF4149 domain-containing protein -
QUE64_RS05955 (PHIN7_11520) 1128317..1128643 - 327 WP_286224964.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QUE64_RS05960 (PHIN7_11530) 1128643..1128897 - 255 WP_286224965.1 antitoxin Antitoxin
QUE64_RS05965 (PHIN7_11540) 1128962..1129444 - 483 WP_286224966.1 transcription elongation factor GreA -
QUE64_RS05970 (PHIN7_11550) 1129483..1132731 - 3249 WP_286224967.1 carbamoyl-phosphate synthase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-105)

Antitoxin

Antitoxin PemI-like

(1-84)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11514.49 Da        Isoelectric Point: 10.3155

>T44570 WP_286224964.1 NZ_AP028138:c1128643-1128317 [Polynucleobacter sp. HIN7]
MKRGDIYLVSLDPTAGHEQKGYRPVLVVSPAPFNQLTKTPIVVPISTGGQFARVAGFAVELVGTKTVGIARCDQPRTLDL
AARKAKRIETVSATVIDEVLAKLATLVT

Download         Length: 327 bp

>T44570 NZ_AP028138:c1128643-1128317 [Polynucleobacter sp. HIN7]
ATGAAGCGAGGCGATATTTATTTGGTATCTCTTGATCCAACCGCTGGCCATGAGCAAAAAGGGTATCGACCCGTATTGGT
AGTGTCACCAGCACCATTTAATCAATTAACCAAGACCCCAATCGTTGTACCGATCTCCACTGGAGGTCAGTTTGCGCGGG
TGGCAGGGTTTGCAGTTGAGCTGGTTGGAACTAAAACTGTTGGTATTGCGCGCTGCGATCAACCTCGCACACTAGACCTT
GCAGCGCGCAAAGCAAAACGAATTGAGACGGTGTCGGCGACTGTGATTGATGAGGTCTTGGCTAAACTAGCAACCTTAGT
TACCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9146.75 Da        Isoelectric Point: 6.9469

>AT44570 WP_286224965.1 NZ_AP028138:c1128897-1128643 [Polynucleobacter sp. HIN7]
MHTNLRKVGGSVMLAVSPVFLKELQITCGSTVDVALKDGQLVVRPIAKSKYELADLLAQCDPKAKMPSEDRVWLDSPPIG
NEIL

Download         Length: 255 bp

>AT44570 NZ_AP028138:c1128897-1128643 [Polynucleobacter sp. HIN7]
ATGCATACCAATTTAAGAAAGGTTGGAGGTTCAGTGATGCTGGCGGTGTCCCCGGTTTTCCTTAAAGAACTTCAGATCAC
TTGCGGCTCGACCGTTGATGTCGCCCTAAAGGACGGGCAATTGGTCGTTCGACCCATCGCAAAGTCGAAGTACGAACTCG
CTGATTTATTAGCGCAATGCGATCCTAAAGCAAAAATGCCAAGCGAGGATCGGGTTTGGTTGGATAGCCCCCCGATCGGC
AATGAGATTCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References