Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 1066253..1066760 Replicon chromosome
Accession NZ_AP028138
Organism Polynucleobacter sp. HIN7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QUE64_RS05640 Protein ID WP_286224913.1
Coordinates 1066503..1066760 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag QUE64_RS05635 Protein ID WP_286224912.1
Coordinates 1066253..1066516 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE64_RS05600 (PHIN7_10850) 1061722..1062231 + 510 WP_286224904.1 DUF2796 domain-containing protein -
QUE64_RS05605 (PHIN7_10860) 1062232..1062933 + 702 WP_286224905.1 ABC transporter ATP-binding protein -
QUE64_RS05610 (PHIN7_10870) 1062933..1064165 + 1233 WP_286224906.1 ABC transporter permease -
QUE64_RS05615 (PHIN7_10880) 1064162..1064701 + 540 WP_286224907.1 DUF3299 domain-containing protein -
QUE64_RS05620 (PHIN7_10890) 1064692..1065348 - 657 WP_286224908.1 MIP/aquaporin family protein -
QUE64_RS05625 (PHIN7_10900) 1065345..1065833 - 489 WP_286224909.1 arsenate reductase ArsC -
QUE64_RS05630 (PHIN7_10910) 1065824..1066153 - 330 WP_286224910.1 metalloregulator ArsR/SmtB family transcription factor -
QUE64_RS05635 (PHIN7_10920) 1066253..1066516 + 264 WP_286224912.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QUE64_RS05640 1066503..1066760 + 258 WP_286224913.1 type II toxin-antitoxin system YafQ family toxin Toxin
QUE64_RS05645 (PHIN7_10930) 1066807..1067460 - 654 WP_286224914.1 DUF502 domain-containing protein -
QUE64_RS05650 (PHIN7_10940) 1067497..1068195 - 699 WP_286226183.1 pirin family protein -
QUE64_RS05655 (PHIN7_10950) 1068199..1068753 - 555 WP_286224915.1 flavodoxin family protein -
QUE64_RS05660 (PHIN7_10960) 1068785..1069201 - 417 WP_286223118.1 MarR family transcriptional regulator -
QUE64_RS05665 (PHIN7_10970) 1069337..1070224 - 888 WP_286223119.1 protease HtpX -
QUE64_RS05670 (PHIN7_10980) 1070325..1070741 - 417 WP_286224916.1 DUF4149 domain-containing protein -
QUE64_RS05675 (PHIN7_10990) 1070707..1070961 - 255 WP_286223121.1 TIGR03643 family protein -
QUE64_RS05680 (PHIN7_11000) 1071007..1071702 + 696 WP_286224917.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-85)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10312.09 Da        Isoelectric Point: 10.8178

>T44569 WP_286224913.1 NZ_AP028138:1066503-1066760 [Polynucleobacter sp. HIN7]
MRTIERTSKFKRDFKRELKGNHKQSLTSDLTLILKLLIADKKLPSRYRDHSLIGDWRDHRDCHIKPDLVLIYRKPDDFRL
QLVRL

Download         Length: 258 bp

>T44569 NZ_AP028138:1066503-1066760 [Polynucleobacter sp. HIN7]
ATGCGGACGATTGAGCGGACCAGTAAATTCAAGCGCGACTTTAAAAGAGAACTCAAAGGAAACCACAAACAATCACTAAC
AAGTGATTTAACTCTGATTCTTAAATTATTGATTGCAGATAAAAAGCTGCCCAGTCGGTATCGGGATCATTCGCTGATTG
GCGATTGGAGAGATCATCGAGACTGTCACATCAAGCCTGATTTAGTACTCATATACCGCAAGCCAGATGATTTCAGGCTT
CAGCTTGTTCGACTTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9577.19 Da        Isoelectric Point: 6.3351

>AT44569 WP_286224912.1 NZ_AP028138:1066253-1066516 [Polynucleobacter sp. HIN7]
MVANAVVRARIDETIKEEATAVLAAMGLTPSSAFRIMMTKIAKEKALPFEPLIPNPETISAMKEARKGRLKSFRSIDDLM
NDLNADD

Download         Length: 264 bp

>AT44569 NZ_AP028138:1066253-1066516 [Polynucleobacter sp. HIN7]
ATGGTCGCAAATGCAGTGGTCCGAGCCAGGATTGATGAAACGATTAAAGAGGAAGCCACAGCAGTACTTGCTGCTATGGG
TCTCACTCCATCTTCAGCATTTAGGATCATGATGACCAAAATCGCTAAGGAGAAGGCTCTTCCCTTTGAGCCGTTGATTC
CAAATCCTGAAACTATTTCAGCAATGAAAGAGGCTAGGAAAGGAAGATTAAAGTCCTTTCGTTCAATTGACGATTTAATG
AATGATTTAAATGCGGACGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References