Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 1163841..1164421 Replicon chromosome
Accession NZ_AP028137
Organism Polynucleobacter sp. HIN6

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QUE66_RS06015 Protein ID WP_286223175.1
Coordinates 1163841..1164167 (-) Length 109 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QUE66_RS06020 Protein ID WP_286223176.1
Coordinates 1164167..1164421 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE66_RS05990 (PHIN6_11560) 1159261..1160136 - 876 WP_286223171.1 dihydropteroate synthase -
QUE66_RS05995 (PHIN6_11570) 1160139..1162025 - 1887 WP_108508702.1 ATP-dependent zinc metalloprotease FtsH -
QUE66_RS06000 (PHIN6_11580) 1162188..1162853 - 666 WP_286223172.1 RlmE family RNA methyltransferase -
QUE66_RS06005 (PHIN6_11590) 1162909..1163364 + 456 WP_286223173.1 YhbY family RNA-binding protein -
QUE66_RS06010 (PHIN6_11600) 1163332..1163832 - 501 WP_286223174.1 DUF4149 domain-containing protein -
QUE66_RS06015 (PHIN6_11610) 1163841..1164167 - 327 WP_286223175.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QUE66_RS06020 (PHIN6_11620) 1164167..1164421 - 255 WP_286223176.1 antitoxin Antitoxin
QUE66_RS06025 (PHIN6_11630) 1164486..1164968 - 483 WP_108508707.1 transcription elongation factor GreA -
QUE66_RS06030 (PHIN6_11640) 1165007..1168255 - 3249 WP_286223177.1 carbamoyl-phosphate synthase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-105)

Antitoxin

Antitoxin PemI-like

(1-84)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11528.47 Da        Isoelectric Point: 10.0519

>T44567 WP_286223175.1 NZ_AP028137:c1164167-1163841 [Polynucleobacter sp. HIN6]
MKRGDIYLVSLDPTAGHEQKGYRPVLVVSPAPFNQLTKTPIVVPISTGGQFARVAGFAVELVGAKTVGIARCDQPRTLDL
AARKAKRVETVSETVIDEVLAKLATLVT

Download         Length: 327 bp

>T44567 NZ_AP028137:c1164167-1163841 [Polynucleobacter sp. HIN6]
ATGAAGCGAGGCGATATTTATTTGGTATCTCTTGATCCAACGGCTGGCCATGAGCAAAAAGGGTATCGACCCGTATTGGT
AGTGTCACCAGCACCGTTTAATCAATTAACCAAGACCCCAATCGTTGTACCGATCTCCACTGGAGGTCAGTTTGCGCGGG
TGGCAGGATTTGCAGTTGAGCTGGTTGGAGCTAAAACTGTTGGTATTGCACGCTGCGATCAACCTCGCACACTAGACCTC
GCGGCTCGCAAAGCAAAACGCGTTGAGACCGTGTCGGAGACTGTGATTGATGAGGTCTTGGCTAAACTAGCAACCTTAGT
TACCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9218.82 Da        Isoelectric Point: 7.8297

>AT44567 WP_286223176.1 NZ_AP028137:c1164421-1164167 [Polynucleobacter sp. HIN6]
MHTNLRKVGGSVMLAVSPVFLKELQITCGSTVDVALKDGQLVVRPIAKRKYELADLLAQCDPKAKMPSEDRQWLDSAPIG
NEIL

Download         Length: 255 bp

>AT44567 NZ_AP028137:c1164421-1164167 [Polynucleobacter sp. HIN6]
ATGCATACCAATTTAAGAAAGGTTGGCGGTTCAGTGATGCTGGCAGTGTCCCCGGTTTTCCTGAAAGAACTTCAGATCAC
TTGCGGCTCGACCGTTGATGTCGCCCTAAAGGACGGGCAATTGGTCGTTCGACCCATCGCAAAGCGGAAGTACGAACTCG
CTGATTTATTAGCGCAATGCGATCCCAAAGCAAAAATGCCAAGCGAGGATCGCCAGTGGTTGGATAGCGCCCCGATCGGC
AATGAGATTCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References