Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1135781..1136336 Replicon chromosome
Accession NZ_AP028137
Organism Polynucleobacter sp. HIN6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QUE66_RS05865 Protein ID WP_286223149.1
Coordinates 1135781..1136092 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QUE66_RS05870 Protein ID WP_286223150.1
Coordinates 1136079..1136336 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE66_RS05845 (PHIN6_11300) 1131179..1132861 - 1683 WP_286223145.1 amidohydrolase -
QUE66_RS05850 (PHIN6_11310) 1133298..1133897 + 600 WP_286223146.1 GNAT family protein -
QUE66_RS05855 (PHIN6_11320) 1134104..1135117 - 1014 WP_286223147.1 GNAT family N-acetyltransferase -
QUE66_RS05860 (PHIN6_11330) 1135157..1135519 - 363 WP_286223148.1 Rap1a/Tai family immunity protein -
QUE66_RS05865 (PHIN6_11340) 1135781..1136092 - 312 WP_286223149.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QUE66_RS05870 1136079..1136336 - 258 WP_286223150.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QUE66_RS05880 (PHIN6_11360) 1136703..1137545 + 843 WP_286223151.1 class I SAM-dependent methyltransferase -
QUE66_RS05885 (PHIN6_11370) 1137568..1138911 + 1344 WP_286223152.1 amino acid permease -
QUE66_RS05890 (PHIN6_11380) 1138965..1139819 + 855 WP_286223153.1 hypothetical protein -
QUE66_RS05900 1140007..1140420 + 414 WP_286223154.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-75)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12132.37 Da        Isoelectric Point: 10.4970

>T44566 WP_286223149.1 NZ_AP028137:c1136092-1135781 [Polynucleobacter sp. HIN6]
MRIYKLEFHVLAKKEWDKLDGSLKEQFKKQLEKRLVTPHIPSALLSRELEGCYKIKLRTSGYRLVYEVVDKRVTVIVIAV
GKRDKDEAYQKAVKRYIHKVSGK

Download         Length: 312 bp

>T44566 NZ_AP028137:c1136092-1135781 [Polynucleobacter sp. HIN6]
TTGAGGATCTATAAGTTAGAGTTCCATGTTTTAGCCAAAAAAGAGTGGGATAAGTTGGATGGTTCTTTAAAAGAACAGTT
CAAGAAGCAATTAGAAAAACGTCTAGTGACACCTCATATTCCATCGGCACTGTTAAGCCGGGAGTTAGAAGGTTGCTACA
AAATTAAATTACGAACTAGTGGCTATCGTCTTGTCTATGAAGTAGTAGATAAGCGAGTAACAGTGATTGTGATAGCGGTT
GGTAAGCGAGATAAAGATGAGGCTTACCAAAAAGCAGTAAAACGATATATCCATAAAGTGTCGGGTAAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9335.86 Da        Isoelectric Point: 7.2017

>AT44566 WP_286223150.1 NZ_AP028137:c1136336-1136079 [Polynucleobacter sp. HIN6]
MNILTPIHAGTTISVTDLRKLTPSKIIEQAGGNPVAILSHNKPEAYLLSAKVYETILDALDDLELIKTVEKRRGGKTIRV
NLEDL

Download         Length: 258 bp

>AT44566 NZ_AP028137:c1136336-1136079 [Polynucleobacter sp. HIN6]
ATGAATATACTTACACCGATTCATGCAGGGACAACAATCAGCGTGACTGATTTAAGAAAGTTAACGCCGAGTAAAATCAT
TGAGCAAGCAGGGGGTAATCCTGTTGCCATCCTCAGTCACAACAAGCCTGAGGCATATTTGTTATCCGCGAAAGTATACG
AAACCATTTTAGATGCTTTGGATGACCTTGAATTAATTAAAACGGTTGAAAAAAGACGTGGTGGTAAAACTATTAGGGTA
AATCTTGAGGATCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References