44469

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc(toxin)
Location 2683054..2683622 Replicon chromosome
Accession NZ_AP028067
Organism Vibrio sp. FE10

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag QUF19_RS11935 Protein ID WP_286298880.1
Coordinates 2683224..2683622 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag QUF19_RS11930 Protein ID WP_286293924.1
Coordinates 2683054..2683224 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUF19_RS11900 2678724..2680391 + 1668 WP_171762950.1 Eco57I restriction-modification methylase domain-containing protein -
QUF19_RS11905 2680392..2681111 + 720 WP_171762949.1 PaeR7I family type II restriction endonuclease -
QUF19_RS11910 2681141..2681314 - 174 Protein_2292 regulator -
QUF19_RS11915 2681656..2681958 - 303 WP_171762948.1 type II toxin-antitoxin system RelE/ParE family toxin -
QUF19_RS11920 2681958..2682218 - 261 WP_016799688.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
QUF19_RS11925 2682436..2682975 + 540 WP_286293922.1 recombinase family protein -
QUF19_RS11930 2683054..2683224 + 171 WP_286293924.1 acetyltransferase Antitoxin
QUF19_RS11935 2683224..2683622 + 399 WP_286298880.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
QUF19_RS11940 2683804..2684757 - 954 WP_286293925.1 hypothetical protein -
QUF19_RS11945 2684971..2686503 + 1533 WP_286291968.1 IS21 family transposase -
QUF19_RS11950 2686514..2687236 + 723 WP_286291966.1 IS21-like element helper ATPase IstB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2633542..2692737 59195


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(1-129)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14567.45 Da        Isoelectric Point: 3.7136

>T44469 WP_286298880.1 NZ_AP028067:2683224-2683622 [Vibrio sp. FE10]
MDIICFPFERVIEINTFILESEPGMSGAVDIPKLQGALGRIDNAIVYDGLDDIFEIAAKYTTSIAMSHALPDANKRTGLM
VALEYLSLNDFELTSDNDLLADAVRDLVLTEISETDFADILYAQYAQENNLA

Download         Length: 399 bp

>T44469 NZ_AP028067:2683224-2683622 [Vibrio sp. FE10]
ATGGATATTATTTGCTTTCCATTTGAGCGAGTCATCGAAATAAATACATTTATATTGGAGAGTGAACCTGGTATGAGTGG
GGCTGTTGATATTCCCAAGTTGCAAGGTGCATTAGGTCGAATTGATAATGCAATTGTTTACGATGGCTTAGATGATATCT
TTGAAATTGCAGCTAAATATACTACAAGTATTGCGATGTCACATGCCCTTCCAGATGCGAATAAAAGAACCGGCTTAATG
GTTGCTTTGGAGTATTTGTCTTTGAACGACTTTGAGTTGACCAGTGATAATGATTTATTAGCTGATGCTGTTCGAGATTT
GGTGCTTACTGAGATTTCGGAAACTGATTTCGCTGATATTTTATACGCTCAGTATGCACAGGAAAACAATCTTGCTTAA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6464.60 Da        Isoelectric Point: 10.9229

>AT44469 WP_286293924.1 NZ_AP028067:2683054-2683224 [Vibrio sp. FE10]
MNKRIESYGVDVVKRPKIKATRKLDLSGTYGQQIVKSESKLALRTHRKTFEKLADM

Download         Length: 171 bp

>AT44469 NZ_AP028067:2683054-2683224 [Vibrio sp. FE10]
ATGAATAAGAGAATTGAATCTTATGGCGTAGATGTTGTTAAACGACCTAAGATTAAAGCTACAAGAAAGCTTGATCTTTC
TGGTACTTATGGACAGCAGATTGTTAAGTCAGAGTCTAAGTTAGCCTTGAGAACTCATCGTAAGACGTTTGAGAAGTTGG
CTGACATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References