Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | phd-doc/Doc(toxin) |
| Location | 2683054..2683622 | Replicon | chromosome |
| Accession | NZ_AP028067 | ||
| Organism | Vibrio sp. FE10 | ||
Toxin (Protein)
| Gene name | doc | Uniprot ID | - |
| Locus tag | QUF19_RS11935 | Protein ID | WP_286298880.1 |
| Coordinates | 2683224..2683622 (+) | Length | 133 a.a. |
Antitoxin (Protein)
| Gene name | phd | Uniprot ID | - |
| Locus tag | QUF19_RS11930 | Protein ID | WP_286293924.1 |
| Coordinates | 2683054..2683224 (+) | Length | 57 a.a. |
Genomic Context
Location: 2678724..2680391 (1668 bp)
Type: Others
Protein ID: WP_171762950.1
Type: Others
Protein ID: WP_171762950.1
Location: 2680392..2681111 (720 bp)
Type: Others
Protein ID: WP_171762949.1
Type: Others
Protein ID: WP_171762949.1
Location: 2682436..2682975 (540 bp)
Type: Others
Protein ID: WP_286293922.1
Type: Others
Protein ID: WP_286293922.1
Location: 2683054..2683224 (171 bp)
Type: Antitoxin
Protein ID: WP_286293924.1
Type: Antitoxin
Protein ID: WP_286293924.1
Location: 2683224..2683622 (399 bp)
Type: Toxin
Protein ID: WP_286298880.1
Type: Toxin
Protein ID: WP_286298880.1
Location: 2684971..2686503 (1533 bp)
Type: Others
Protein ID: WP_286291968.1
Type: Others
Protein ID: WP_286291968.1
Location: 2686514..2687236 (723 bp)
Type: Others
Protein ID: WP_286291966.1
Type: Others
Protein ID: WP_286291966.1
Location: 2681141..2681314 (174 bp)
Type: Others
Protein ID: Protein_2292
Type: Others
Protein ID: Protein_2292
Location: 2681656..2681958 (303 bp)
Type: Others
Protein ID: WP_171762948.1
Type: Others
Protein ID: WP_171762948.1
Location: 2681958..2682218 (261 bp)
Type: Others
Protein ID: WP_016799688.1
Type: Others
Protein ID: WP_016799688.1
Location: 2683804..2684757 (954 bp)
Type: Others
Protein ID: WP_286293925.1
Type: Others
Protein ID: WP_286293925.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUF19_RS11900 | 2678724..2680391 | + | 1668 | WP_171762950.1 | Eco57I restriction-modification methylase domain-containing protein | - |
| QUF19_RS11905 | 2680392..2681111 | + | 720 | WP_171762949.1 | PaeR7I family type II restriction endonuclease | - |
| QUF19_RS11910 | 2681141..2681314 | - | 174 | Protein_2292 | regulator | - |
| QUF19_RS11915 | 2681656..2681958 | - | 303 | WP_171762948.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| QUF19_RS11920 | 2681958..2682218 | - | 261 | WP_016799688.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| QUF19_RS11925 | 2682436..2682975 | + | 540 | WP_286293922.1 | recombinase family protein | - |
| QUF19_RS11930 | 2683054..2683224 | + | 171 | WP_286293924.1 | acetyltransferase | Antitoxin |
| QUF19_RS11935 | 2683224..2683622 | + | 399 | WP_286298880.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin |
| QUF19_RS11940 | 2683804..2684757 | - | 954 | WP_286293925.1 | hypothetical protein | - |
| QUF19_RS11945 | 2684971..2686503 | + | 1533 | WP_286291968.1 | IS21 family transposase | - |
| QUF19_RS11950 | 2686514..2687236 | + | 723 | WP_286291966.1 | IS21-like element helper ATPase IstB | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2633542..2692737 | 59195 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 133 a.a. Molecular weight: 14567.45 Da Isoelectric Point: 3.7136
>T44469 WP_286298880.1 NZ_AP028067:2683224-2683622 [Vibrio sp. FE10]
MDIICFPFERVIEINTFILESEPGMSGAVDIPKLQGALGRIDNAIVYDGLDDIFEIAAKYTTSIAMSHALPDANKRTGLM
VALEYLSLNDFELTSDNDLLADAVRDLVLTEISETDFADILYAQYAQENNLA
MDIICFPFERVIEINTFILESEPGMSGAVDIPKLQGALGRIDNAIVYDGLDDIFEIAAKYTTSIAMSHALPDANKRTGLM
VALEYLSLNDFELTSDNDLLADAVRDLVLTEISETDFADILYAQYAQENNLA
Download Length: 399 bp
>T44469 NZ_AP028067:2683224-2683622 [Vibrio sp. FE10]
ATGGATATTATTTGCTTTCCATTTGAGCGAGTCATCGAAATAAATACATTTATATTGGAGAGTGAACCTGGTATGAGTGG
GGCTGTTGATATTCCCAAGTTGCAAGGTGCATTAGGTCGAATTGATAATGCAATTGTTTACGATGGCTTAGATGATATCT
TTGAAATTGCAGCTAAATATACTACAAGTATTGCGATGTCACATGCCCTTCCAGATGCGAATAAAAGAACCGGCTTAATG
GTTGCTTTGGAGTATTTGTCTTTGAACGACTTTGAGTTGACCAGTGATAATGATTTATTAGCTGATGCTGTTCGAGATTT
GGTGCTTACTGAGATTTCGGAAACTGATTTCGCTGATATTTTATACGCTCAGTATGCACAGGAAAACAATCTTGCTTAA
ATGGATATTATTTGCTTTCCATTTGAGCGAGTCATCGAAATAAATACATTTATATTGGAGAGTGAACCTGGTATGAGTGG
GGCTGTTGATATTCCCAAGTTGCAAGGTGCATTAGGTCGAATTGATAATGCAATTGTTTACGATGGCTTAGATGATATCT
TTGAAATTGCAGCTAAATATACTACAAGTATTGCGATGTCACATGCCCTTCCAGATGCGAATAAAAGAACCGGCTTAATG
GTTGCTTTGGAGTATTTGTCTTTGAACGACTTTGAGTTGACCAGTGATAATGATTTATTAGCTGATGCTGTTCGAGATTT
GGTGCTTACTGAGATTTCGGAAACTGATTTCGCTGATATTTTATACGCTCAGTATGCACAGGAAAACAATCTTGCTTAA
Antitoxin
Download Length: 57 a.a. Molecular weight: 6464.60 Da Isoelectric Point: 10.9229
>AT44469 WP_286293924.1 NZ_AP028067:2683054-2683224 [Vibrio sp. FE10]
MNKRIESYGVDVVKRPKIKATRKLDLSGTYGQQIVKSESKLALRTHRKTFEKLADM
MNKRIESYGVDVVKRPKIKATRKLDLSGTYGQQIVKSESKLALRTHRKTFEKLADM
Download Length: 171 bp
>AT44469 NZ_AP028067:2683054-2683224 [Vibrio sp. FE10]
ATGAATAAGAGAATTGAATCTTATGGCGTAGATGTTGTTAAACGACCTAAGATTAAAGCTACAAGAAAGCTTGATCTTTC
TGGTACTTATGGACAGCAGATTGTTAAGTCAGAGTCTAAGTTAGCCTTGAGAACTCATCGTAAGACGTTTGAGAAGTTGG
CTGACATGTGA
ATGAATAAGAGAATTGAATCTTATGGCGTAGATGTTGTTAAACGACCTAAGATTAAAGCTACAAGAAAGCTTGATCTTTC
TGGTACTTATGGACAGCAGATTGTTAAGTCAGAGTCTAAGTTAGCCTTGAGAACTCATCGTAAGACGTTTGAGAAGTTGG
CTGACATGTGA