44452

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-PHD
Location 2035539..2036198 Replicon chromosome
Accession NZ_AP028056
Organism Brooklawnia sp. SH051

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QUE25_RS09225 Protein ID WP_286264284.1
Coordinates 2035539..2035931 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QUE25_RS09230 Protein ID WP_286264285.1
Coordinates 2035935..2036198 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE25_RS09205 (brsh051_18290) 2032476..2032811 + 336 WP_286264277.1 winged helix-turn-helix domain-containing protein -
QUE25_RS09210 (brsh051_18300) 2032821..2033798 + 978 WP_286264278.1 SRPBCC family protein -
QUE25_RS09215 (brsh051_18310) 2033861..2034646 + 786 WP_286264280.1 chlorite dismutase family protein -
QUE25_RS09220 (brsh051_18320) 2034656..2035495 - 840 WP_286264282.1 HAD-IIB family hydrolase -
QUE25_RS09225 (brsh051_18330) 2035539..2035931 - 393 WP_286264284.1 type II toxin-antitoxin system VapC family toxin Toxin
QUE25_RS09230 (brsh051_18340) 2035935..2036198 - 264 WP_286264285.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QUE25_RS09235 (brsh051_18350) 2036362..2038578 - 2217 WP_286264286.1 heavy metal translocating P-type ATPase -
QUE25_RS09240 (brsh051_18360) 2038616..2039659 + 1044 WP_286264288.1 nitrilase-related carbon-nitrogen hydrolase -
QUE25_RS09245 (brsh051_18370) 2039953..2040876 + 924 WP_286264290.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-41)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 13998.14 Da        Isoelectric Point: 5.6438

>T44452 WP_286264284.1 NZ_AP028056:c2035931-2035539 [Brooklawnia sp. SH051]
VAYYIDTSALVKLVVAKPETAALRSWIAAEHPSLVSSDLARTELLRVVRRVLPDRLEQARAVLDSITLTKVVTPVFESAG
LVDPTILRTLDAVHLASALELGDDLDGIVSYDERMAGAARSHGITVVAPR

Download         Length: 393 bp

>T44452 NZ_AP028056:c2035931-2035539 [Brooklawnia sp. SH051]
GTGGCTTACTACATCGACACCTCGGCTCTGGTGAAGCTTGTCGTCGCCAAGCCCGAGACTGCGGCTCTGCGCTCCTGGAT
CGCAGCTGAGCATCCGAGCCTGGTGTCCTCGGATCTGGCCCGCACCGAGTTGCTGCGAGTCGTCCGCCGGGTGCTGCCCG
ATCGGCTCGAGCAGGCCAGGGCGGTGCTCGACTCGATCACCCTGACGAAGGTGGTCACCCCGGTCTTCGAGTCTGCCGGG
CTGGTCGATCCCACTATCCTGCGGACTCTGGACGCGGTGCACCTGGCGTCCGCGCTCGAACTCGGCGACGACCTCGACGG
GATCGTCAGCTACGACGAGCGGATGGCCGGCGCCGCGCGCAGTCACGGCATCACGGTCGTCGCGCCGCGCTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 8993.16 Da        Isoelectric Point: 4.5932

>AT44452 WP_286264285.1 NZ_AP028056:c2036198-2035935 [Brooklawnia sp. SH051]
MSEVGIRALKQNASAVVADAAAGQTITITDRGRPVALITPIPSSPLQGMLDSGQARPPRSDISDLPDPAPGPDLASELAG
MRNAERY

Download         Length: 264 bp

>AT44452 NZ_AP028056:c2036198-2035935 [Brooklawnia sp. SH051]
ATGAGCGAGGTTGGGATTCGTGCACTGAAGCAGAACGCCTCCGCTGTCGTCGCTGACGCGGCAGCCGGCCAGACCATCAC
CATCACCGACCGCGGACGACCGGTCGCCCTGATCACACCGATTCCGTCGTCCCCACTACAGGGCATGCTCGACAGCGGAC
AGGCTCGGCCACCTAGGTCGGACATCAGCGATCTGCCGGACCCGGCCCCGGGACCGGACCTGGCGTCCGAACTGGCCGGC
ATGCGCAATGCGGAGAGGTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References