Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 97885..98411 | Replicon | plasmid pTMTA98321 |
| Accession | NZ_AP028051 | ||
| Organism | Phytobacter diazotrophicus strain TA9832 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | S1EXL1 |
| Locus tag | QUE83_RS27800 | Protein ID | WP_000323025.1 |
| Coordinates | 98124..98411 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | J5W3H0 |
| Locus tag | QUE83_RS27795 | Protein ID | WP_004196370.1 |
| Coordinates | 97885..98124 (+) | Length | 80 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUE83_RS27760 | 93222..93414 | - | 193 | Protein_102 | MFS transporter | - |
| QUE83_RS27765 (PDTA9832_54800) | 93444..94421 | + | 978 | WP_004196334.1 | chromate resistance protein | - |
| QUE83_RS27770 (PDTA9832_54810) | 94378..95754 | + | 1377 | WP_004196363.1 | chromate efflux transporter | - |
| QUE83_RS27775 (PDTA9832_54820) | 95785..96474 | - | 690 | WP_004196322.1 | hypothetical protein | - |
| QUE83_RS27780 (PDTA9832_54830) | 96488..97225 | - | 738 | WP_008460272.1 | HupE/UreJ family protein | - |
| QUE83_RS27785 (PDTA9832_54840) | 97269..97634 | - | 366 | WP_009651956.1 | hypothetical protein | - |
| QUE83_RS27790 | 97762..97860 | - | 99 | Protein_108 | protein YdfV | - |
| QUE83_RS27795 (PDTA9832_54850) | 97885..98124 | + | 240 | WP_004196370.1 | type II toxin-antitoxin system antitoxin RelB | Antitoxin |
| QUE83_RS27800 (PDTA9832_54860) | 98124..98411 | + | 288 | WP_000323025.1 | type II toxin-antitoxin system mRNA interferase RelE | Toxin |
| QUE83_RS27805 (PDTA9832_54870) | 98483..98641 | + | 159 | WP_014063856.1 | type I toxin-antitoxin system Hok family toxin | - |
| QUE83_RS27810 (PDTA9832_54880) | 98846..99100 | - | 255 | WP_125125755.1 | DUF2767 family protein | - |
| QUE83_RS27815 (PDTA9832_54890) | 99667..100245 | + | 579 | WP_125125756.1 | hypothetical protein | - |
| QUE83_RS27820 (PDTA9832_54900) | 100317..100619 | + | 303 | WP_125125757.1 | hypothetical protein | - |
| QUE83_RS27825 (PDTA9832_54910) | 101345..101647 | + | 303 | WP_047368814.1 | hypothetical protein | - |
| QUE83_RS27830 (PDTA9832_54920) | 101661..102479 | + | 819 | WP_172600722.1 | DUF932 domain-containing protein | - |
| QUE83_RS27835 (PDTA9832_54930) | 102496..103041 | - | 546 | WP_125125759.1 | lytic transglycosylase domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..174856 | 174856 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11225.22 Da Isoelectric Point: 10.1967
>T44450 WP_000323025.1 NZ_AP028051:98124-98411 [Phytobacter diazotrophicus]
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL
Download Length: 288 bp
>T44450 NZ_AP028051:98124-98411 [Phytobacter diazotrophicus]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
Antitoxin
Download Length: 80 a.a. Molecular weight: 9018.43 Da Isoelectric Point: 4.3894
>AT44450 WP_004196370.1 NZ_AP028051:97885-98124 [Phytobacter diazotrophicus]
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLCNPKPVRVTLDEL
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLCNPKPVRVTLDEL
Download Length: 240 bp
>AT44450 NZ_AP028051:97885-98124 [Phytobacter diazotrophicus]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTTGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTTGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|