Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2833538..2834460 Replicon chromosome
Accession NZ_AP028050
Organism Phytobacter diazotrophicus strain TA9832

Toxin (Protein)


Gene name - Uniprot ID A0A348DED3
Locus tag QUE83_RS13660 Protein ID WP_039079059.1
Coordinates 2833984..2834460 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A348DED2
Locus tag QUE83_RS13655 Protein ID WP_071194172.1
Coordinates 2833538..2833984 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE83_RS13645 (2829211) 2829211..2832258 - 3048 WP_125124690.1 formate dehydrogenase-N subunit alpha -
QUE83_RS13650 (2832591) 2832591..2833472 + 882 WP_125124691.1 aromatic amino acid DMT transporter YddG -
QUE83_RS13655 (2833538) 2833538..2833984 + 447 WP_071194172.1 DUF2384 domain-containing protein Antitoxin
QUE83_RS13660 (2833984) 2833984..2834460 + 477 WP_039079059.1 RES family NAD+ phosphorylase Toxin
QUE83_RS13665 (2834444) 2834444..2835946 - 1503 WP_125124692.1 MFS transporter -
QUE83_RS13670 (2836059) 2836059..2836649 + 591 WP_125124693.1 TetR family transcriptional regulator -
QUE83_RS13675 (2836631) 2836631..2837473 - 843 WP_125124694.1 N-hydroxyarylamine O-acetyltransferase -
QUE83_RS13680 (2837549) 2837549..2839204 - 1656 WP_125124695.1 iron ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(5-150)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(28-90)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 17725.30 Da        Isoelectric Point: 5.2290

>T44438 WP_039079059.1 NZ_AP028050:2833984-2834460 [Phytobacter diazotrophicus]
METVTFWRLVKERYALTAFDGYGARTFGGRWNSPGHECVYLGESKALCVLETLVHLEIEDIAQGYCFLTLDVPRNLIATL
DLTALPEDWKADPPPVSTQHIGDEWLASKQNGLVLRVPSTITGEWNALFNPEHPQAAKVLKSVKSEPFMLDPRLSRPC

Download         Length: 477 bp

>T44438 NZ_AP028050:2833984-2834460 [Phytobacter diazotrophicus]
ATGGAAACTGTCACCTTCTGGCGTCTGGTCAAAGAACGCTATGCGCTGACCGCCTTCGACGGTTACGGCGCGCGAACCTT
TGGCGGACGCTGGAATTCACCGGGGCATGAATGCGTCTACCTGGGTGAATCAAAAGCTCTCTGCGTGCTGGAAACACTGG
TACATCTTGAGATTGAAGATATCGCCCAGGGCTACTGTTTCTTAACCCTCGATGTACCACGTAATCTTATCGCGACGCTG
GATTTGACCGCCCTGCCCGAAGACTGGAAAGCTGACCCGCCGCCTGTTTCCACGCAACACATCGGCGATGAGTGGCTGGC
ATCAAAGCAAAACGGGCTGGTACTGCGCGTCCCCAGTACCATCACCGGCGAATGGAACGCGCTGTTTAACCCCGAACACC
CACAGGCGGCGAAAGTCCTCAAAAGCGTAAAGTCCGAACCCTTTATGCTGGATCCCCGTCTTAGCCGTCCTTGCTAG

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 15690.07 Da        Isoelectric Point: 8.9810

>AT44438 WP_071194172.1 NZ_AP028050:2833538-2833984 [Phytobacter diazotrophicus]
MQLYTPGVRAIPHDLLSILGLPATAIAAHDSINAGLSAGVLRDIAGAVSLDEITLCRMAGIDRNTYSRRLNSAEKRFSPE
QSARVYTLARVISAARELFEGDSERMATWLNKPAKGLGGKKPAELLSTPAGAEAVLTLIGRLEHGVIG

Download         Length: 447 bp

>AT44438 NZ_AP028050:2833538-2833984 [Phytobacter diazotrophicus]
ATGCAACTCTATACACCGGGCGTACGCGCGATCCCGCACGACCTGCTCAGCATCCTGGGGCTGCCCGCCACGGCGATTGC
CGCTCATGACAGCATTAATGCCGGTCTGAGTGCAGGTGTGTTGCGTGATATCGCTGGCGCCGTCTCTCTTGATGAAATCA
CGCTGTGCCGAATGGCTGGCATTGATCGTAATACCTATAGCCGCAGGCTTAACAGCGCGGAAAAACGCTTTTCACCAGAA
CAGAGTGCGCGCGTCTACACGCTGGCACGAGTGATCAGCGCCGCTCGTGAGTTATTTGAAGGTGACAGCGAGCGTATGGC
CACCTGGCTCAATAAACCCGCGAAAGGCCTTGGCGGTAAAAAACCCGCAGAGCTTCTCTCGACACCCGCCGGTGCGGAAG
CGGTACTGACATTGATTGGTCGCCTTGAGCATGGTGTGATCGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A348DED3

Antitoxin

Source ID Structure
AlphaFold DB A0A348DED2

References