Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2833538..2834460 Replicon chromosome
Accession NZ_AP028050
Organism Phytobacter diazotrophicus strain TA9832

Toxin (Protein)


Gene name - Uniprot ID A0A348DED3
Locus tag QUE83_RS13660 Protein ID WP_039079059.1
Coordinates 2833984..2834460 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A348DED2
Locus tag QUE83_RS13655 Protein ID WP_071194172.1
Coordinates 2833538..2833984 (+) Length 149 a.a.

Genomic Context

QUE83_RS13650QUE83_RS13655QUE83_RS13660QUE83_RS13670QUE83_RS13645QUE83_RS13665QUE83_RS13675QUE83_RS13680
Location: 2832591..2833472 (882 bp)
Type: Others
Protein ID: WP_125124691.1
Location: 2833538..2833984 (447 bp)
Type: Antitoxin
Protein ID: WP_071194172.1
Location: 2833984..2834460 (477 bp)
Type: Toxin
Protein ID: WP_039079059.1
Location: 2836059..2836649 (591 bp)
Type: Others
Protein ID: WP_125124693.1
Location: 2829211..2832258 (3048 bp)
Type: Others
Protein ID: WP_125124690.1
Location: 2834444..2835946 (1503 bp)
Type: Others
Protein ID: WP_125124692.1
Location: 2836631..2837473 (843 bp)
Type: Others
Protein ID: WP_125124694.1
Location: 2837549..2839204 (1656 bp)
Type: Others
Protein ID: WP_125124695.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QUE83_RS13645 (2829211)2829211..2832258-3048WP_125124690.1formate dehydrogenase-N subunit alpha-
QUE83_RS13650 (2832591)2832591..2833472+882WP_125124691.1aromatic amino acid DMT transporter YddG-
QUE83_RS13655 (2833538)2833538..2833984+447WP_071194172.1DUF2384 domain-containing proteinAntitoxin
QUE83_RS13660 (2833984)2833984..2834460+477WP_039079059.1RES family NAD+ phosphorylaseToxin
QUE83_RS13665 (2834444)2834444..2835946-1503WP_125124692.1MFS transporter-
QUE83_RS13670 (2836059)2836059..2836649+591WP_125124693.1TetR family transcriptional regulator-
QUE83_RS13675 (2836631)2836631..2837473-843WP_125124694.1N-hydroxyarylamine O-acetyltransferase-
QUE83_RS13680 (2837549)2837549..2839204-1656WP_125124695.1iron ABC transporter permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(5-150)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(28-90)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 17725.30 Da        Isoelectric Point: 5.2290

>T44438 WP_039079059.1 NZ_AP028050:2833984-2834460 [Phytobacter diazotrophicus]
METVTFWRLVKERYALTAFDGYGARTFGGRWNSPGHECVYLGESKALCVLETLVHLEIEDIAQGYCFLTLDVPRNLIATL
DLTALPEDWKADPPPVSTQHIGDEWLASKQNGLVLRVPSTITGEWNALFNPEHPQAAKVLKSVKSEPFMLDPRLSRPC

Download         Length: 477 bp

>T44438 NZ_AP028050:2833984-2834460 [Phytobacter diazotrophicus]
ATGGAAACTGTCACCTTCTGGCGTCTGGTCAAAGAACGCTATGCGCTGACCGCCTTCGACGGTTACGGCGCGCGAACCTT
TGGCGGACGCTGGAATTCACCGGGGCATGAATGCGTCTACCTGGGTGAATCAAAAGCTCTCTGCGTGCTGGAAACACTGG
TACATCTTGAGATTGAAGATATCGCCCAGGGCTACTGTTTCTTAACCCTCGATGTACCACGTAATCTTATCGCGACGCTG
GATTTGACCGCCCTGCCCGAAGACTGGAAAGCTGACCCGCCGCCTGTTTCCACGCAACACATCGGCGATGAGTGGCTGGC
ATCAAAGCAAAACGGGCTGGTACTGCGCGTCCCCAGTACCATCACCGGCGAATGGAACGCGCTGTTTAACCCCGAACACC
CACAGGCGGCGAAAGTCCTCAAAAGCGTAAAGTCCGAACCCTTTATGCTGGATCCCCGTCTTAGCCGTCCTTGCTAG

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 15690.07 Da        Isoelectric Point: 8.9810

>AT44438 WP_071194172.1 NZ_AP028050:2833538-2833984 [Phytobacter diazotrophicus]
MQLYTPGVRAIPHDLLSILGLPATAIAAHDSINAGLSAGVLRDIAGAVSLDEITLCRMAGIDRNTYSRRLNSAEKRFSPE
QSARVYTLARVISAARELFEGDSERMATWLNKPAKGLGGKKPAELLSTPAGAEAVLTLIGRLEHGVIG

Download         Length: 447 bp

>AT44438 NZ_AP028050:2833538-2833984 [Phytobacter diazotrophicus]
ATGCAACTCTATACACCGGGCGTACGCGCGATCCCGCACGACCTGCTCAGCATCCTGGGGCTGCCCGCCACGGCGATTGC
CGCTCATGACAGCATTAATGCCGGTCTGAGTGCAGGTGTGTTGCGTGATATCGCTGGCGCCGTCTCTCTTGATGAAATCA
CGCTGTGCCGAATGGCTGGCATTGATCGTAATACCTATAGCCGCAGGCTTAACAGCGCGGAAAAACGCTTTTCACCAGAA
CAGAGTGCGCGCGTCTACACGCTGGCACGAGTGATCAGCGCCGCTCGTGAGTTATTTGAAGGTGACAGCGAGCGTATGGC
CACCTGGCTCAATAAACCCGCGAAAGGCCTTGGCGGTAAAAAACCCGCAGAGCTTCTCTCGACACCCGCCGGTGCGGAAG
CGGTACTGACATTGATTGGTCGCCTTGAGCATGGTGTGATCGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A348DED3

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A348DED2

References