Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 2785506..2786149 Replicon chromosome
Accession NZ_AP028050
Organism Phytobacter diazotrophicus strain TA9832

Toxin (Protein)


Gene name vagD Uniprot ID A0A348DE83
Locus tag QUE83_RS13410 Protein ID WP_071194208.1
Coordinates 2785733..2786149 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID A0A348DE82
Locus tag QUE83_RS13405 Protein ID WP_071194209.1
Coordinates 2785506..2785736 (+) Length 77 a.a.

Genomic Context

QUE83_RS13385QUE83_RS13390QUE83_RS13395QUE83_RS13405QUE83_RS13410QUE83_RS13420QUE83_RS13425QUE83_RS13430QUE83_RS13400QUE83_RS13415
Location: 2781668..2782045 (378 bp)
Type: Others
Protein ID: WP_108701294.1
Location: 2782116..2783069 (954 bp)
Type: Others
Protein ID: WP_039079008.1
Location: 2783121..2783885 (765 bp)
Type: Others
Protein ID: WP_039079009.1
Location: 2785506..2785736 (231 bp)
Type: Antitoxin
Protein ID: WP_071194209.1
Location: 2785733..2786149 (417 bp)
Type: Toxin
Protein ID: WP_071194208.1
Location: 2787104..2788102 (999 bp)
Type: Others
Protein ID: WP_039079015.1
Location: 2788102..2789139 (1038 bp)
Type: Others
Protein ID: WP_125124673.1
Location: 2789139..2789900 (762 bp)
Type: Others
Protein ID: WP_071194204.1
Location: 2783962..2785248 (1287 bp)
Type: Others
Protein ID: WP_125124672.1
Location: 2786412..2786819 (408 bp)
Type: Others
Protein ID: WP_125125677.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QUE83_RS13385 (2781668)2781668..2782045+378WP_108701294.1VOC family protein-
QUE83_RS13390 (2782116)2782116..2783069+954WP_039079008.12-hydroxyacid dehydrogenase-
QUE83_RS13395 (2783121)2783121..2783885+765WP_039079009.1SDR family oxidoreductase-
QUE83_RS13400 (2783962)2783962..2785248-1287WP_125124672.1MFS transporter-
QUE83_RS13405 (2785506)2785506..2785736+231WP_071194209.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
QUE83_RS13410 (2785733)2785733..2786149+417WP_071194208.1PIN domain-containing proteinToxin
QUE83_RS13415 (2786412)2786412..2786819-408WP_125125677.1nuclear transport factor 2 family protein-
QUE83_RS13420 (2787104)2787104..2788102+999WP_039079015.1ABC transporter substrate-binding protein-
QUE83_RS13425 (2788102)2788102..2789139+1038WP_125124673.1iron chelate uptake ABC transporter family permease subunit-
QUE83_RS13430 (2789139)2789139..2789900+762WP_071194204.1ABC transporter ATP-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-129)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15050.57 Da        Isoelectric Point: 9.2345

>T44437 WP_071194208.1 NZ_AP028050:2785733-2786149 [Phytobacter diazotrophicus]
MKKTFMLDTNICSFIMREHPESVIKRLEQAVLRNNRIVVSAITYAEMRFGAIGKKASPHHAKLVDAFCARLDAVLAWDRA
AVDATTQIKLALALAGTPIGPNDTAIAGHAIAAGVVLVTNNTREFERVPGLILEDWAK

Download         Length: 417 bp

>T44437 NZ_AP028050:2785733-2786149 [Phytobacter diazotrophicus]
ATGAAGAAAACCTTTATGCTCGACACTAATATTTGCTCATTCATCATGCGCGAGCATCCGGAAAGCGTTATTAAGCGTCT
GGAGCAGGCAGTGTTGCGCAACAATCGAATCGTAGTATCGGCTATCACCTATGCGGAAATGCGCTTCGGCGCGATCGGTA
AAAAGGCGTCGCCGCATCATGCGAAGCTGGTTGATGCGTTCTGTGCTCGCCTTGATGCCGTGCTCGCCTGGGACCGGGCG
GCAGTGGATGCCACTACGCAAATAAAGCTTGCGCTGGCGTTGGCTGGTACGCCGATTGGTCCGAACGATACCGCGATTGC
CGGGCATGCTATTGCCGCTGGCGTCGTGCTGGTAACAAATAATACGCGGGAGTTTGAGCGGGTGCCGGGTCTGATTCTGG
AAGACTGGGCAAAGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8783.91 Da        Isoelectric Point: 4.3654

>AT44437 WP_071194209.1 NZ_AP028050:2785506-2785736 [Phytobacter diazotrophicus]
MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIIREGDCIILRPVRPTWSSFAQLEKADPDFMAEREDVVSDEGRFDL

Download         Length: 231 bp

>AT44437 NZ_AP028050:2785506-2785736 [Phytobacter diazotrophicus]
ATGCGAACCGTATCCATCTTCAAAAACGGCAACAATCGTGCCATCCGTCTGCCTCGCGATCTGGATTTCGAAGGAGTGAG
CGAACTGGAGATCATCAGGGAAGGGGACTGCATCATCCTGCGCCCGGTGCGACCGACGTGGAGTTCTTTCGCGCAATTAG
AAAAAGCCGACCCGGATTTTATGGCAGAACGTGAAGATGTGGTCAGTGATGAGGGACGCTTTGATCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A348DE83

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A348DE82

References