Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pemIK/PRK09812-MazE |
| Location | 1952204..1952794 | Replicon | chromosome |
| Accession | NZ_AP028050 | ||
| Organism | Phytobacter diazotrophicus strain TA9832 | ||
Toxin (Protein)
| Gene name | pemK | Uniprot ID | - |
| Locus tag | QUE83_RS09125 | Protein ID | WP_125124239.1 |
| Coordinates | 1952462..1952794 (+) | Length | 111 a.a. |
Antitoxin (Protein)
| Gene name | pemI | Uniprot ID | - |
| Locus tag | QUE83_RS09120 | Protein ID | WP_125124238.1 |
| Coordinates | 1952204..1952461 (+) | Length | 86 a.a. |
Genomic Context
Location: 1950869..1951780 (912 bp)
Type: Others
Protein ID: WP_125124237.1
Type: Others
Protein ID: WP_125124237.1
Location: 1952204..1952461 (258 bp)
Type: Antitoxin
Protein ID: WP_125124238.1
Type: Antitoxin
Protein ID: WP_125124238.1
Location: 1952462..1952794 (333 bp)
Type: Toxin
Protein ID: WP_125124239.1
Type: Toxin
Protein ID: WP_125124239.1
Location: 1953195..1954628 (1434 bp)
Type: Others
Protein ID: WP_103245488.1
Type: Others
Protein ID: WP_103245488.1
Location: 1955357..1956817 (1461 bp)
Type: Others
Protein ID: WP_125124241.1
Type: Others
Protein ID: WP_125124241.1
Location: 1947811..1948146 (336 bp)
Type: Others
Protein ID: WP_041851877.1
Type: Others
Protein ID: WP_041851877.1
Location: 1948273..1948563 (291 bp)
Type: Others
Protein ID: WP_079496374.1
Type: Others
Protein ID: WP_079496374.1
Location: 1948821..1949360 (540 bp)
Type: Others
Protein ID: WP_079496546.1
Type: Others
Protein ID: WP_079496546.1
Location: 1949659..1950768 (1110 bp)
Type: Others
Protein ID: WP_125124236.1
Type: Others
Protein ID: WP_125124236.1
Location: 1954913..1955140 (228 bp)
Type: Others
Protein ID: WP_125124240.1
Type: Others
Protein ID: WP_125124240.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUE83_RS09095 (1947811) | 1947811..1948146 | - | 336 | WP_041851877.1 | gamma-glutamylcyclotransferase family protein | - |
| QUE83_RS09100 (1948273) | 1948273..1948563 | - | 291 | WP_079496374.1 | DUF3601 domain-containing protein | - |
| QUE83_RS09105 (1948821) | 1948821..1949360 | - | 540 | WP_079496546.1 | ester cyclase | - |
| QUE83_RS09110 (1949659) | 1949659..1950768 | - | 1110 | WP_125124236.1 | alkene reductase | - |
| QUE83_RS09115 (1950869) | 1950869..1951780 | + | 912 | WP_125124237.1 | LysR family transcriptional regulator | - |
| QUE83_RS09120 (1952204) | 1952204..1952461 | + | 258 | WP_125124238.1 | antitoxin | Antitoxin |
| QUE83_RS09125 (1952462) | 1952462..1952794 | + | 333 | WP_125124239.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| QUE83_RS09135 (1953195) | 1953195..1954628 | + | 1434 | WP_103245488.1 | EmmdR/YeeO family multidrug/toxin efflux MATE transporter | - |
| QUE83_RS09145 (1954913) | 1954913..1955140 | - | 228 | WP_125124240.1 | hypothetical protein | - |
| QUE83_RS09150 (1955357) | 1955357..1956817 | + | 1461 | WP_125124241.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1934201..2033606 | 99405 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 111 a.a. Molecular weight: 11781.49 Da Isoelectric Point: 6.9812
>T44435 WP_125124239.1 NZ_AP028050:1952462-1952794 [Phytobacter diazotrophicus]
MDRGEIWLVSLDPTTGHEQSGKRPVLIVSPASFNALTRLPVVVPVTSGGNFARAAGFAVSLEGAGTKTTGVIRCDQPRTI
DMDARNDKRLERIPDAVVNEVLARLEAILS
MDRGEIWLVSLDPTTGHEQSGKRPVLIVSPASFNALTRLPVVVPVTSGGNFARAAGFAVSLEGAGTKTTGVIRCDQPRTI
DMDARNDKRLERIPDAVVNEVLARLEAILS
Download Length: 333 bp
>T44435 NZ_AP028050:1952462-1952794 [Phytobacter diazotrophicus]
ATGGACAGAGGGGAAATCTGGCTCGTCTCACTGGATCCGACCACCGGGCATGAACAAAGCGGAAAACGTCCAGTGCTTAT
CGTTTCTCCCGCGTCATTTAATGCACTCACCCGTTTGCCCGTTGTTGTTCCGGTCACCAGTGGCGGAAACTTTGCCCGAG
CGGCGGGTTTTGCCGTCTCACTGGAAGGTGCGGGAACGAAAACCACGGGTGTGATTCGCTGCGATCAGCCCAGAACCATT
GATATGGACGCCCGAAACGACAAGCGTCTGGAACGTATACCCGATGCTGTCGTGAATGAAGTGCTGGCCCGACTGGAAGC
CATTCTGAGTTGA
ATGGACAGAGGGGAAATCTGGCTCGTCTCACTGGATCCGACCACCGGGCATGAACAAAGCGGAAAACGTCCAGTGCTTAT
CGTTTCTCCCGCGTCATTTAATGCACTCACCCGTTTGCCCGTTGTTGTTCCGGTCACCAGTGGCGGAAACTTTGCCCGAG
CGGCGGGTTTTGCCGTCTCACTGGAAGGTGCGGGAACGAAAACCACGGGTGTGATTCGCTGCGATCAGCCCAGAACCATT
GATATGGACGCCCGAAACGACAAGCGTCTGGAACGTATACCCGATGCTGTCGTGAATGAAGTGCTGGCCCGACTGGAAGC
CATTCTGAGTTGA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9272.74 Da Isoelectric Point: 4.5799
>AT44435 WP_125124238.1 NZ_AP028050:1952204-1952461 [Phytobacter diazotrophicus]
MYIARLKKVGGSVMLAVPPAVLKTLGLSTDSEVGMTIENGCLIIEPQKRPHYSLEELLAQCDPHAEISEEDRQWIDGPAA
GKELL
MYIARLKKVGGSVMLAVPPAVLKTLGLSTDSEVGMTIENGCLIIEPQKRPHYSLEELLAQCDPHAEISEEDRQWIDGPAA
GKELL
Download Length: 258 bp
>AT44435 NZ_AP028050:1952204-1952461 [Phytobacter diazotrophicus]
ATGTATATCGCTCGCCTTAAAAAGGTTGGAGGATCCGTCATGCTGGCGGTTCCTCCTGCCGTATTGAAAACCCTGGGGCT
GTCGACGGATAGCGAAGTGGGTATGACCATTGAGAATGGCTGCCTGATTATTGAACCCCAGAAACGGCCACATTACTCGC
TTGAGGAATTGCTGGCGCAGTGTGATCCGCACGCCGAAATCAGCGAAGAGGATCGGCAATGGATTGATGGGCCTGCGGCG
GGCAAGGAGCTTCTGTAA
ATGTATATCGCTCGCCTTAAAAAGGTTGGAGGATCCGTCATGCTGGCGGTTCCTCCTGCCGTATTGAAAACCCTGGGGCT
GTCGACGGATAGCGAAGTGGGTATGACCATTGAGAATGGCTGCCTGATTATTGAACCCCAGAAACGGCCACATTACTCGC
TTGAGGAATTGCTGGCGCAGTGTGATCCGCACGCCGAAATCAGCGAAGAGGATCGGCAATGGATTGATGGGCCTGCGGCG
GGCAAGGAGCTTCTGTAA