Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 96727..97253 | Replicon | plasmid pTMTA97592 |
| Accession | NZ_AP028049 | ||
| Organism | Phytobacter diazotrophicus strain TA9759 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | S1EXL1 |
| Locus tag | QUE80_RS28970 | Protein ID | WP_000323025.1 |
| Coordinates | 96966..97253 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | J5W3H0 |
| Locus tag | QUE80_RS28965 | Protein ID | WP_004196370.1 |
| Coordinates | 96727..96966 (+) | Length | 80 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUE80_RS28930 | 92064..92256 | - | 193 | Protein_99 | MFS transporter | - |
| QUE80_RS28935 (PDTA9759_57200) | 92286..93263 | + | 978 | WP_004196334.1 | chromate resistance protein | - |
| QUE80_RS28940 (PDTA9759_57210) | 93220..94596 | + | 1377 | WP_004196363.1 | chromate efflux transporter | - |
| QUE80_RS28945 (PDTA9759_57220) | 94627..95316 | - | 690 | WP_004196322.1 | hypothetical protein | - |
| QUE80_RS28950 (PDTA9759_57230) | 95330..96067 | - | 738 | WP_008460272.1 | HupE/UreJ family protein | - |
| QUE80_RS28955 (PDTA9759_57240) | 96111..96476 | - | 366 | WP_009651956.1 | hypothetical protein | - |
| QUE80_RS28960 | 96604..96702 | - | 99 | Protein_105 | protein YdfV | - |
| QUE80_RS28965 (PDTA9759_57250) | 96727..96966 | + | 240 | WP_004196370.1 | type II toxin-antitoxin system antitoxin RelB | Antitoxin |
| QUE80_RS28970 (PDTA9759_57260) | 96966..97253 | + | 288 | WP_000323025.1 | type II toxin-antitoxin system mRNA interferase RelE | Toxin |
| QUE80_RS28975 (PDTA9759_57270) | 97325..97483 | + | 159 | WP_014063856.1 | type I toxin-antitoxin system Hok family toxin | - |
| QUE80_RS28980 (PDTA9759_57280) | 97688..97942 | - | 255 | WP_125125755.1 | DUF2767 family protein | - |
| QUE80_RS28985 (PDTA9759_57290) | 98509..99087 | + | 579 | WP_125125756.1 | hypothetical protein | - |
| QUE80_RS28990 (PDTA9759_57300) | 99159..99461 | + | 303 | WP_125125757.1 | hypothetical protein | - |
| QUE80_RS28995 (PDTA9759_57310) | 100187..100489 | + | 303 | WP_047368814.1 | hypothetical protein | - |
| QUE80_RS29000 (PDTA9759_57320) | 100503..101321 | + | 819 | WP_172600722.1 | DUF932 domain-containing protein | - |
| QUE80_RS29005 (PDTA9759_57330) | 101338..101883 | - | 546 | WP_125125759.1 | lytic transglycosylase domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..173698 | 173698 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11225.22 Da Isoelectric Point: 10.1967
>T44431 WP_000323025.1 NZ_AP028049:96966-97253 [Phytobacter diazotrophicus]
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL
Download Length: 288 bp
>T44431 NZ_AP028049:96966-97253 [Phytobacter diazotrophicus]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
Antitoxin
Download Length: 80 a.a. Molecular weight: 9018.43 Da Isoelectric Point: 4.3894
>AT44431 WP_004196370.1 NZ_AP028049:96727-96966 [Phytobacter diazotrophicus]
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLCNPKPVRVTLDEL
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLCNPKPVRVTLDEL
Download Length: 240 bp
>AT44431 NZ_AP028049:96727-96966 [Phytobacter diazotrophicus]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTTGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTTGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|