Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 935030..935693 Replicon chromosome
Accession NZ_AP028047
Organism Phytobacter diazotrophicus strain TA9759

Toxin (Protein)


Gene name cptA Uniprot ID A0A348D8P9
Locus tag QUE80_RS04460 Protein ID WP_039077972.1
Coordinates 935277..935693 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A348D8P8
Locus tag QUE80_RS04455 Protein ID WP_039077973.1
Coordinates 935030..935296 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE80_RS04430 (930208) 930208..931641 - 1434 WP_079497183.1 6-phospho-beta-glucosidase -
QUE80_RS04435 (931765) 931765..932493 - 729 WP_039077977.1 MurR/RpiR family transcriptional regulator -
QUE80_RS04440 (932546) 932546..932857 + 312 WP_039077976.1 N(4)-acetylcytidine aminohydrolase -
QUE80_RS04445 (933020) 933020..933679 + 660 WP_125123906.1 hemolysin III family protein -
QUE80_RS04450 (933797) 933797..934780 - 984 WP_071196007.1 tRNA-modifying protein YgfZ -
QUE80_RS04455 (935030) 935030..935296 + 267 WP_039077973.1 FAD assembly factor SdhE Antitoxin
QUE80_RS04460 (935277) 935277..935693 + 417 WP_039077972.1 protein YgfX Toxin
QUE80_RS04465 (935696) 935696..936217 - 522 WP_125123907.1 flavodoxin FldB -
QUE80_RS04470 (936319) 936319..937215 + 897 WP_039077970.1 site-specific tyrosine recombinase XerD -
QUE80_RS04475 (937240) 937240..937953 + 714 WP_039077969.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QUE80_RS04480 (937959) 937959..939692 + 1734 WP_125123908.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16438.33 Da        Isoelectric Point: 11.4778

>T44414 WP_039077972.1 NZ_AP028047:935277-935693 [Phytobacter diazotrophicus]
VVLWQSDIRVSWRSQWLSLLLHGLMAAFVLLLPWPLSYTPLWLLLLSLVVFDSVRSQRRINACQGEIKLLMDARLRWQGV
EWEIVGTPWMLNIGMILRLRREKDGRRQHLWLAADSMDAQEWRDLRRLISQQSAQRQH

Download         Length: 417 bp

>T44414 NZ_AP028047:935277-935693 [Phytobacter diazotrophicus]
GTGGTCCTGTGGCAATCTGATATACGCGTCTCATGGCGCTCACAGTGGCTCTCACTTTTACTCCATGGCTTGATGGCGGC
TTTCGTGTTGCTGTTACCCTGGCCATTGAGTTATACGCCGCTTTGGTTACTGCTTTTGTCACTGGTGGTGTTCGACAGCG
TACGGAGTCAGCGCCGCATTAATGCCTGTCAGGGAGAGATCAAACTGTTGATGGATGCACGTTTGCGCTGGCAAGGCGTG
GAGTGGGAAATCGTCGGAACACCATGGATGCTGAATATTGGCATGATTCTGCGTTTGCGTCGGGAAAAAGATGGTCGCCG
ACAGCATCTGTGGCTGGCCGCAGATAGCATGGATGCGCAAGAGTGGCGTGATTTGCGCCGACTGATTTCGCAACAATCGG
CGCAGCGTCAGCACTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.03 Da        Isoelectric Point: 6.2199

>AT44414 WP_039077973.1 NZ_AP028047:935030-935296 [Phytobacter diazotrophicus]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDDKRVFVRLLQSDDPDLFNWLMNHGKPQDEALQRMIQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT44414 NZ_AP028047:935030-935296 [Phytobacter diazotrophicus]
ATGGATATTAACAACAAAGCCCGTATTCATTGGGCATGTCGGCGCGGAATGCGTGAGCTGGATATTTCCATCATGCCTTT
CTTTGAACATGAATATGATTCGCTGAGTGATGATGACAAACGTGTGTTTGTGCGTCTTCTGCAGAGCGATGACCCTGATT
TATTTAACTGGCTGATGAATCACGGCAAACCTCAGGACGAGGCGTTGCAGCGAATGATCCAGTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A348D8P9

Antitoxin

Source ID Structure
AlphaFold DB A0A348D8P8

References