Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 841303..842084 Replicon chromosome
Accession NZ_AP028047
Organism Phytobacter diazotrophicus strain TA9759

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag QUE80_RS04010 Protein ID WP_125123871.1
Coordinates 841593..842084 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag QUE80_RS04005 Protein ID WP_125123870.1
Coordinates 841303..841596 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE80_RS03995 (838299) 838299..838439 + 141 Protein_785 DUF1778 domain-containing protein -
QUE80_RS04000 (838513) 838513..840702 - 2190 WP_125123869.1 TonB-dependent siderophore receptor -
QUE80_RS04005 (841303) 841303..841596 + 294 WP_125123870.1 DUF1778 domain-containing protein Antitoxin
QUE80_RS04010 (841593) 841593..842084 + 492 WP_125123871.1 GNAT family N-acetyltransferase Toxin
QUE80_RS04015 (842149) 842149..842643 + 495 WP_232034376.1 hypothetical protein -
QUE80_RS04020 (842833) 842833..843348 - 516 WP_125123872.1 hypothetical protein -
QUE80_RS04025 (843503) 843503..844654 + 1152 Protein_791 IS3 family transposase -
QUE80_RS04030 (845064) 845064..845660 - 597 WP_047749132.1 hypothetical protein -
QUE80_RS04035 (845660) 845660..846004 - 345 WP_047749131.1 hypothetical protein -
QUE80_RS04040 (846016) 846016..846564 - 549 WP_047749130.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-144)

Antitoxin

Vibrio phage ICP1, Orf50

(2-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17721.58 Da        Isoelectric Point: 7.2655

>T44413 WP_125123871.1 NZ_AP028047:841593-842084 [Phytobacter diazotrophicus]
MISAPEPLHTGHILTPFCCGMDSMDKWLKQRAMKNQVTGASRTFVCCGSDSNVQAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLV
ESI

Download         Length: 492 bp

>T44413 NZ_AP028047:841593-842084 [Phytobacter diazotrophicus]
ATGATCTCTGCTCCAGAACCGCTTCATACCGGGCATATTCTTACCCCGTTCTGTTGCGGCATGGATTCTATGGATAAGTG
GCTCAAACAACGGGCGATGAAAAATCAGGTCACTGGCGCATCGCGTACCTTTGTATGTTGCGGCAGCGATTCTAACGTAC
AGGCGTATTACTCGCTGGCGTCCAGCGCGGTAACGACCAACACCGCCCCCGGTCGCTTTCGTCGCAATATGCCCGATCCG
ATCCCGGTGGTGGTGCTGGGACGTCTGGCTGTGGATCAATCACTGCACGGGCAGGGCGTCGGGCGGGCGCTGGTTCGCGA
CGCCGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTGCACGCCCTGTCGGATGAAGCGC
GGGAGTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTATTTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10931.55 Da        Isoelectric Point: 8.6351

>AT44413 WP_125123870.1 NZ_AP028047:841303-841596 [Phytobacter diazotrophicus]
MPAANSMAMKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYEEFLARLDQAPAPN
AALRKTMQTPAPWEQEK

Download         Length: 294 bp

>AT44413 NZ_AP028047:841303-841596 [Phytobacter diazotrophicus]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACTCTGAATCTGCGCATCAGGCCCGCCGAGCGTGATCTTATCGA
CCGGGCAGCGAAGGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCCGCCCGCGCTGCCGCTGAGGAAGCGTTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATGAGGAGTTTCTGGCTCGTCTAGATCAGGCGCCTGCGCCTAAC
GCTGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References