Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 98945..99471 | Replicon | plasmid pTMTA97301 |
| Accession | NZ_AP028042 | ||
| Organism | Phytobacter diazotrophicus strain TA9730 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | S1EXL1 |
| Locus tag | QUE90_RS27490 | Protein ID | WP_000323025.1 |
| Coordinates | 99184..99471 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | J5W3H0 |
| Locus tag | QUE90_RS27485 | Protein ID | WP_004196370.1 |
| Coordinates | 98945..99184 (+) | Length | 80 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUE90_RS27450 | 94282..94474 | - | 193 | Protein_104 | MFS transporter | - |
| QUE90_RS27455 (PDTA9730_54190) | 94504..95481 | + | 978 | WP_004196334.1 | chromate resistance protein | - |
| QUE90_RS27460 (PDTA9730_54200) | 95438..96814 | + | 1377 | WP_004196363.1 | chromate efflux transporter | - |
| QUE90_RS27465 (PDTA9730_54210) | 96845..97534 | - | 690 | WP_004196322.1 | hypothetical protein | - |
| QUE90_RS27470 (PDTA9730_54220) | 97548..98285 | - | 738 | WP_008460272.1 | HupE/UreJ family protein | - |
| QUE90_RS27475 (PDTA9730_54230) | 98329..98694 | - | 366 | WP_009651956.1 | hypothetical protein | - |
| QUE90_RS27480 | 98822..98920 | - | 99 | Protein_110 | protein YdfV | - |
| QUE90_RS27485 (PDTA9730_54240) | 98945..99184 | + | 240 | WP_004196370.1 | type II toxin-antitoxin system antitoxin RelB | Antitoxin |
| QUE90_RS27490 (PDTA9730_54250) | 99184..99471 | + | 288 | WP_000323025.1 | type II toxin-antitoxin system mRNA interferase RelE | Toxin |
| QUE90_RS27495 (PDTA9730_54260) | 99543..99701 | + | 159 | WP_014063856.1 | type I toxin-antitoxin system Hok family toxin | - |
| QUE90_RS27500 (PDTA9730_54270) | 99906..100160 | - | 255 | WP_125125755.1 | DUF2767 family protein | - |
| QUE90_RS27505 (PDTA9730_54280) | 100727..101305 | + | 579 | WP_125125756.1 | hypothetical protein | - |
| QUE90_RS27510 (PDTA9730_54290) | 101377..101679 | + | 303 | WP_125125757.1 | hypothetical protein | - |
| QUE90_RS27515 (PDTA9730_54300) | 102405..102707 | + | 303 | WP_047368814.1 | hypothetical protein | - |
| QUE90_RS27520 (PDTA9730_54310) | 102721..103539 | + | 819 | WP_172600722.1 | DUF932 domain-containing protein | - |
| QUE90_RS27525 (PDTA9730_54320) | 103556..104101 | - | 546 | WP_125125759.1 | lytic transglycosylase domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..175916 | 175916 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11225.22 Da Isoelectric Point: 10.1967
>T44410 WP_000323025.1 NZ_AP028042:99184-99471 [Phytobacter diazotrophicus]
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL
Download Length: 288 bp
>T44410 NZ_AP028042:99184-99471 [Phytobacter diazotrophicus]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
Antitoxin
Download Length: 80 a.a. Molecular weight: 9018.43 Da Isoelectric Point: 4.3894
>AT44410 WP_004196370.1 NZ_AP028042:98945-99184 [Phytobacter diazotrophicus]
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLCNPKPVRVTLDEL
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLCNPKPVRVTLDEL
Download Length: 240 bp
>AT44410 NZ_AP028042:98945-99184 [Phytobacter diazotrophicus]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTTGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTTGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|