Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 1951784..1952374 Replicon chromosome
Accession NZ_AP028041
Organism Phytobacter diazotrophicus strain TA9730

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QUE90_RS09125 Protein ID WP_125124239.1
Coordinates 1952042..1952374 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QUE90_RS09120 Protein ID WP_125124238.1
Coordinates 1951784..1952041 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE90_RS09095 (1947391) 1947391..1947726 - 336 WP_041851877.1 gamma-glutamylcyclotransferase family protein -
QUE90_RS09100 (1947853) 1947853..1948143 - 291 WP_079496374.1 DUF3601 domain-containing protein -
QUE90_RS09105 (1948401) 1948401..1948940 - 540 WP_079496546.1 ester cyclase -
QUE90_RS09110 (1949239) 1949239..1950348 - 1110 WP_125124236.1 alkene reductase -
QUE90_RS09115 (1950449) 1950449..1951360 + 912 WP_125124237.1 LysR family transcriptional regulator -
QUE90_RS09120 (1951784) 1951784..1952041 + 258 WP_125124238.1 antitoxin Antitoxin
QUE90_RS09125 (1952042) 1952042..1952374 + 333 WP_125124239.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QUE90_RS09135 (1952775) 1952775..1954208 + 1434 WP_103245488.1 EmmdR/YeeO family multidrug/toxin efflux MATE transporter -
QUE90_RS09145 (1954493) 1954493..1954720 - 228 WP_125124240.1 hypothetical protein -
QUE90_RS09150 (1954937) 1954937..1956397 + 1461 WP_125124241.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin

Antitoxin PemI-like

(5-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11781.49 Da        Isoelectric Point: 6.9812

>T44395 WP_125124239.1 NZ_AP028041:1952042-1952374 [Phytobacter diazotrophicus]
MDRGEIWLVSLDPTTGHEQSGKRPVLIVSPASFNALTRLPVVVPVTSGGNFARAAGFAVSLEGAGTKTTGVIRCDQPRTI
DMDARNDKRLERIPDAVVNEVLARLEAILS

Download         Length: 333 bp

>T44395 NZ_AP028041:1952042-1952374 [Phytobacter diazotrophicus]
ATGGACAGAGGGGAAATCTGGCTCGTCTCACTGGATCCGACCACCGGGCATGAACAAAGCGGAAAACGTCCAGTGCTTAT
CGTTTCTCCCGCGTCATTTAATGCACTCACCCGTTTGCCCGTTGTTGTTCCGGTCACCAGTGGCGGAAACTTTGCCCGAG
CGGCGGGTTTTGCCGTCTCACTGGAAGGTGCGGGAACGAAAACCACGGGTGTGATTCGCTGCGATCAGCCCAGAACCATT
GATATGGACGCCCGAAACGACAAGCGTCTGGAACGTATACCCGATGCTGTCGTGAATGAAGTGCTGGCCCGACTGGAAGC
CATTCTGAGTTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9272.74 Da        Isoelectric Point: 4.5799

>AT44395 WP_125124238.1 NZ_AP028041:1951784-1952041 [Phytobacter diazotrophicus]
MYIARLKKVGGSVMLAVPPAVLKTLGLSTDSEVGMTIENGCLIIEPQKRPHYSLEELLAQCDPHAEISEEDRQWIDGPAA
GKELL

Download         Length: 258 bp

>AT44395 NZ_AP028041:1951784-1952041 [Phytobacter diazotrophicus]
ATGTATATCGCTCGCCTTAAAAAGGTTGGAGGATCCGTCATGCTGGCGGTTCCTCCTGCCGTATTGAAAACCCTGGGGCT
GTCGACGGATAGCGAAGTGGGTATGACCATTGAGAATGGCTGCCTGATTATTGAACCCCAGAAACGGCCACATTACTCGC
TTGAGGAATTGCTGGCGCAGTGTGATCCGCACGCCGAAATCAGCGAAGAGGATCGGCAATGGATTGATGGGCCTGCGGCG
GGCAAGGAGCTTCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References