Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 841302..842083 Replicon chromosome
Accession NZ_AP028041
Organism Phytobacter diazotrophicus strain TA9730

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag QUE90_RS04010 Protein ID WP_125123871.1
Coordinates 841592..842083 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag QUE90_RS04005 Protein ID WP_125123870.1
Coordinates 841302..841595 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE90_RS03995 (838298) 838298..838438 + 141 Protein_785 DUF1778 domain-containing protein -
QUE90_RS04000 (838512) 838512..840701 - 2190 WP_125123869.1 TonB-dependent siderophore receptor -
QUE90_RS04005 (841302) 841302..841595 + 294 WP_125123870.1 DUF1778 domain-containing protein Antitoxin
QUE90_RS04010 (841592) 841592..842083 + 492 WP_125123871.1 GNAT family N-acetyltransferase Toxin
QUE90_RS04015 (842148) 842148..842642 + 495 WP_232034376.1 hypothetical protein -
QUE90_RS04020 (842832) 842832..843347 - 516 WP_125123872.1 hypothetical protein -
QUE90_RS04025 (843502) 843502..844653 + 1152 Protein_791 IS3 family transposase -
QUE90_RS04030 (845063) 845063..845659 - 597 WP_047749132.1 hypothetical protein -
QUE90_RS04035 (845659) 845659..846003 - 345 WP_047749131.1 hypothetical protein -
QUE90_RS04040 (846015) 846015..846563 - 549 WP_047749130.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-144)

Antitoxin

Vibrio phage ICP1, Orf50

(2-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17721.58 Da        Isoelectric Point: 7.2655

>T44393 WP_125123871.1 NZ_AP028041:841592-842083 [Phytobacter diazotrophicus]
MISAPEPLHTGHILTPFCCGMDSMDKWLKQRAMKNQVTGASRTFVCCGSDSNVQAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLV
ESI

Download         Length: 492 bp

>T44393 NZ_AP028041:841592-842083 [Phytobacter diazotrophicus]
ATGATCTCTGCTCCAGAACCGCTTCATACCGGGCATATTCTTACCCCGTTCTGTTGCGGCATGGATTCTATGGATAAGTG
GCTCAAACAACGGGCGATGAAAAATCAGGTCACTGGCGCATCGCGTACCTTTGTATGTTGCGGCAGCGATTCTAACGTAC
AGGCGTATTACTCGCTGGCGTCCAGCGCGGTAACGACCAACACCGCCCCCGGTCGCTTTCGTCGCAATATGCCCGATCCG
ATCCCGGTGGTGGTGCTGGGACGTCTGGCTGTGGATCAATCACTGCACGGGCAGGGCGTCGGGCGGGCGCTGGTTCGCGA
CGCCGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTGCACGCCCTGTCGGATGAAGCGC
GGGAGTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTATTTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10931.55 Da        Isoelectric Point: 8.6351

>AT44393 WP_125123870.1 NZ_AP028041:841302-841595 [Phytobacter diazotrophicus]
MPAANSMAMKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYEEFLARLDQAPAPN
AALRKTMQTPAPWEQEK

Download         Length: 294 bp

>AT44393 NZ_AP028041:841302-841595 [Phytobacter diazotrophicus]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACTCTGAATCTGCGCATCAGGCCCGCCGAGCGTGATCTTATCGA
CCGGGCAGCGAAGGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCCGCCCGCGCTGCCGCTGAGGAAGCGTTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATGAGGAGTTTCTGGCTCGTCTAGATCAGGCGCCTGCGCCTAAC
GCTGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References