Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
Location | 202050..202789 | Replicon | chromosome |
Accession | NZ_AP028041 | ||
Organism | Phytobacter diazotrophicus strain TA9730 |
Toxin (Protein)
Gene name | tacT | Uniprot ID | A0A348D6L8 |
Locus tag | QUE90_RS00975 | Protein ID | WP_039080181.1 |
Coordinates | 202304..202789 (+) | Length | 162 a.a. |
Antitoxin (Protein)
Gene name | tacA | Uniprot ID | A0A348D6L7 |
Locus tag | QUE90_RS00970 | Protein ID | WP_039080180.1 |
Coordinates | 202050..202316 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QUE90_RS00950 (198122) | 198122..198427 | + | 306 | WP_172600614.1 | YsaB family lipoprotein | - |
QUE90_RS00955 (198533) | 198533..199444 | + | 912 | WP_004126458.1 | glycine--tRNA ligase subunit alpha | - |
QUE90_RS00960 (199454) | 199454..201523 | + | 2070 | WP_039080179.1 | glycine--tRNA ligase subunit beta | - |
QUE90_RS00965 (201644) | 201644..201892 | + | 249 | Protein_191 | IS30 family transposase | - |
QUE90_RS00970 (202050) | 202050..202316 | + | 267 | WP_039080180.1 | DUF1778 domain-containing protein | Antitoxin |
QUE90_RS00975 (202304) | 202304..202789 | + | 486 | WP_039080181.1 | GNAT family N-acetyltransferase | Toxin |
QUE90_RS00980 (203375) | 203375..204994 | + | 1620 | WP_107222628.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
QUE90_RS00985 (205038) | 205038..205331 | - | 294 | WP_039080183.1 | HTH-type transcriptional regulator | - |
QUE90_RS00990 (205709) | 205709..206419 | + | 711 | WP_039080184.1 | DUF3053 domain-containing protein | - |
QUE90_RS00995 (206485) | 206485..207459 | - | 975 | WP_071195041.1 | glyoxylate/hydroxypyruvate reductase GhrB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 162 a.a. Molecular weight: 17775.56 Da Isoelectric Point: 10.2934
>T44392 WP_039080181.1 NZ_AP028041:202304-202789 [Phytobacter diazotrophicus]
VGRVTAPEPLSNFHQVAAFVSGEAVLDDWLKQRGLKNQALGAARTFVVCKKDTKQIVGFYSLATGSVNHTETTGNLRRNM
PDPIPVIILARLAVDVSFRGKGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFYIHHGFKPSQTQQRTLFLKLP
Q
VGRVTAPEPLSNFHQVAAFVSGEAVLDDWLKQRGLKNQALGAARTFVVCKKDTKQIVGFYSLATGSVNHTETTGNLRRNM
PDPIPVIILARLAVDVSFRGKGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFYIHHGFKPSQTQQRTLFLKLP
Q
Download Length: 486 bp
>T44392 NZ_AP028041:202304-202789 [Phytobacter diazotrophicus]
GTGGGACGTGTAACAGCGCCAGAGCCTTTATCCAATTTCCATCAGGTGGCGGCGTTTGTTAGCGGTGAAGCTGTGCTCGA
TGATTGGCTAAAGCAGAGAGGCCTCAAAAATCAGGCTCTCGGAGCTGCCCGAACTTTTGTTGTATGTAAGAAAGACACGA
AACAAATAGTCGGTTTTTACTCTTTGGCCACCGGTAGCGTCAACCATACAGAAACTACAGGCAACCTTCGGCGTAACATG
CCAGACCCTATTCCTGTGATTATACTCGCCCGGCTTGCTGTCGACGTCTCCTTTCGTGGAAAAGGGCTTGGCGCTGATTT
ACTCCACGATGCGGTGCTTCGTTGTTATCGAGTTGCTGAAAATATTGGTGTGCGTGCAATCATGGTTCACGCGCTGACGG
AAGAAGCCAAAAATTTCTATATTCACCATGGTTTCAAGCCATCACAAACTCAGCAGCGGACGTTATTCCTTAAACTTCCT
CAATAG
GTGGGACGTGTAACAGCGCCAGAGCCTTTATCCAATTTCCATCAGGTGGCGGCGTTTGTTAGCGGTGAAGCTGTGCTCGA
TGATTGGCTAAAGCAGAGAGGCCTCAAAAATCAGGCTCTCGGAGCTGCCCGAACTTTTGTTGTATGTAAGAAAGACACGA
AACAAATAGTCGGTTTTTACTCTTTGGCCACCGGTAGCGTCAACCATACAGAAACTACAGGCAACCTTCGGCGTAACATG
CCAGACCCTATTCCTGTGATTATACTCGCCCGGCTTGCTGTCGACGTCTCCTTTCGTGGAAAAGGGCTTGGCGCTGATTT
ACTCCACGATGCGGTGCTTCGTTGTTATCGAGTTGCTGAAAATATTGGTGTGCGTGCAATCATGGTTCACGCGCTGACGG
AAGAAGCCAAAAATTTCTATATTCACCATGGTTTCAAGCCATCACAAACTCAGCAGCGGACGTTATTCCTTAAACTTCCT
CAATAG
Antitoxin
Download Length: 89 a.a. Molecular weight: 10090.50 Da Isoelectric Point: 4.3837
>AT44392 WP_039080180.1 NZ_AP028041:202050-202316 [Phytobacter diazotrophicus]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILERRAFNFNDEQYAEFIDMLDAPVADDPVIDKLL
ARKPQWDV
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILERRAFNFNDEQYAEFIDMLDAPVADDPVIDKLL
ARKPQWDV
Download Length: 267 bp
>AT44392 NZ_AP028041:202050-202316 [Phytobacter diazotrophicus]
ATGAAATCAGATGTTCAACTTAACCTTAGAGCCAAGGAATCACAGCGAGCACTCATTGATGCCGCCGCTGAGATCCTGCA
CAAATCACGTACAGATTTCATTCTGGAAATGGCCTGTCAGGCTGCTGAAAATGTGATTCTTGAGCGACGTGCCTTTAATT
TTAACGATGAGCAATATGCAGAGTTCATCGATATGCTCGATGCACCGGTTGCGGATGATCCCGTTATCGACAAACTGCTG
GCAAGGAAACCTCAGTGGGACGTGTAA
ATGAAATCAGATGTTCAACTTAACCTTAGAGCCAAGGAATCACAGCGAGCACTCATTGATGCCGCCGCTGAGATCCTGCA
CAAATCACGTACAGATTTCATTCTGGAAATGGCCTGTCAGGCTGCTGAAAATGTGATTCTTGAGCGACGTGCCTTTAATT
TTAACGATGAGCAATATGCAGAGTTCATCGATATGCTCGATGCACCGGTTGCGGATGATCCCGTTATCGACAAACTGCTG
GCAAGGAAACCTCAGTGGGACGTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A348D6L8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A348D6L7 |