Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | yeeUV (cbtA-cbeA)/CbtA-CbeA |
| Location | 788673..789468 | Replicon | chromosome |
| Accession | NZ_AP027971 | ||
| Organism | Escherichia coli strain VE-V10-F | ||
Toxin (Protein)
| Gene name | yeeV | Uniprot ID | - |
| Locus tag | QQK73_RS03880 | Protein ID | WP_097246722.1 |
| Coordinates | 788673..789047 (-) | Length | 125 a.a. |
Antitoxin (Protein)
| Gene name | yeeU | Uniprot ID | - |
| Locus tag | QQK73_RS03885 | Protein ID | WP_047088564.1 |
| Coordinates | 789094..789468 (-) | Length | 125 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QQK73_RS03845 (783740) | 783740..784339 | + | 600 | WP_001255040.1 | type II secretion system minor pseudopilin GspJ | - |
| QQK73_RS03850 (784342) | 784342..785319 | + | 978 | WP_000633220.1 | type II secretion system minor pseudopilin GspK | - |
| QQK73_RS03855 (785316) | 785316..786494 | + | 1179 | WP_000094970.1 | type II secretion system protein GspL | - |
| QQK73_RS03860 (786496) | 786496..787032 | + | 537 | WP_000942786.1 | GspM family type II secretion system protein YghD | - |
| QQK73_RS03865 (787313) | 787313..787882 | - | 570 | WP_097246725.1 | DUF4942 domain-containing protein | - |
| QQK73_RS03870 (787979) | 787979..788176 | - | 198 | WP_000839281.1 | DUF957 domain-containing protein | - |
| QQK73_RS03875 (788188) | 788188..788676 | - | 489 | WP_000777545.1 | DUF5983 family protein | - |
| QQK73_RS03880 (788673) | 788673..789047 | - | 375 | WP_097246722.1 | TA system toxin CbtA family protein | Toxin |
| QQK73_RS03885 (789094) | 789094..789468 | - | 375 | WP_047088564.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
| QQK73_RS03890 (789548) | 789548..789769 | - | 222 | WP_000692350.1 | DUF987 domain-containing protein | - |
| QQK73_RS03895 (789856) | 789856..790332 | - | 477 | WP_123004421.1 | RadC family protein | - |
| QQK73_RS03900 (790347) | 790347..790826 | - | 480 | WP_097411785.1 | antirestriction protein | - |
| QQK73_RS03905 (791092) | 791092..791910 | - | 819 | WP_001175165.1 | DUF932 domain-containing protein | - |
| QQK73_RS03910 (792000) | 792000..792233 | - | 234 | WP_001278293.1 | DUF905 family protein | - |
| QQK73_RS03915 (792239) | 792239..792916 | - | 678 | WP_001097302.1 | hypothetical protein | - |
| QQK73_RS03920 (793064) | 793064..793744 | - | 681 | WP_001282919.1 | WYL domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 125 a.a. Molecular weight: 13994.95 Da Isoelectric Point: 8.5221
>T44333 WP_097246722.1 NZ_AP027971:c789047-788673 [Escherichia coli]
MKTLSDTHVREVSRCPSPVTIWQTLLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
SAGTSSQLINSIDILRARRATGLMTRSNYRTVNNITLGKHPEKR
MKTLSDTHVREVSRCPSPVTIWQTLLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
SAGTSSQLINSIDILRARRATGLMTRSNYRTVNNITLGKHPEKR
Download Length: 375 bp
>T44333 NZ_AP027971:c789047-788673 [Escherichia coli]
ATGAAAACATTATCCGACACACATGTACGGGAGGTATCTCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGGTTGCTGGACCAGCACTACGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCAGGAACTTCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCACGCCGGGCAACAGGTCTGATGACCCGCAG
CAACTACAGAACGGTAAATAACATTACCCTAGGTAAGCATCCGGAGAAACGATGA
ATGAAAACATTATCCGACACACATGTACGGGAGGTATCTCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGGTTGCTGGACCAGCACTACGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCAGGAACTTCGTCGCAGTTAATCAACAGCATTGATATTCTCCGGGCACGCCGGGCAACAGGTCTGATGACCCGCAG
CAACTACAGAACGGTAAATAACATTACCCTAGGTAAGCATCCGGAGAAACGATGA
Antitoxin
Download Length: 125 a.a. Molecular weight: 13600.33 Da Isoelectric Point: 5.5051
>AT44333 WP_047088564.1 NZ_AP027971:c789468-789094 [Escherichia coli]
VSDTLSGTTLPDDNNDRTWWGLPCTVTPCFGARLVQEGNRLHYLADRAGIRGRFSDADAYHPDQAFPLLMKQLELMLTSG
ELNPRHQHTVTLYAKGLTCEADTLGSCGYVYLAVYPTPAPAITS
VSDTLSGTTLPDDNNDRTWWGLPCTVTPCFGARLVQEGNRLHYLADRAGIRGRFSDADAYHPDQAFPLLMKQLELMLTSG
ELNPRHQHTVTLYAKGLTCEADTLGSCGYVYLAVYPTPAPAITS
Download Length: 375 bp
>AT44333 NZ_AP027971:c789468-789094 [Escherichia coli]
GTGTCAGACACACTCTCCGGGACAACGCTTCCCGACGACAATAACGACCGCACCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTACAGGAAGGCAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGGCGGT
TCAGCGACGCAGATGCATACCATCCGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGACATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCGGCACCCGCAATCACCTCATAA
GTGTCAGACACACTCTCCGGGACAACGCTTCCCGACGACAATAACGACCGCACCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTTGGGGCACGTCTGGTACAGGAAGGCAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGGCGGT
TCAGCGACGCAGATGCATACCATCCGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGACATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCGGCACCCGCAATCACCTCATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|