Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3415380..3416032 Replicon chromosome
Accession NZ_AP027737
Organism Agromyces mangrovi strain NBRC 112812

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QUE38_RS16315 Protein ID WP_286309379.1
Coordinates 3415380..3415778 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QUE38_RS16320 Protein ID WP_286309380.1
Coordinates 3415778..3416032 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE38_RS16285 (GCM10025877_32870) 3410546..3410941 + 396 WP_286309371.1 hypothetical protein -
QUE38_RS16290 (GCM10025877_32880) 3411014..3411460 + 447 WP_286309372.1 DUF2871 domain-containing protein -
QUE38_RS16295 (GCM10025877_32890) 3411477..3411983 - 507 WP_286309373.1 hypothetical protein -
QUE38_RS16300 (GCM10025877_32900) 3411970..3413256 + 1287 WP_286309374.1 molybdopterin-dependent oxidoreductase -
QUE38_RS16305 (GCM10025877_32910) 3413265..3414287 + 1023 WP_286309376.1 molybdopterin-dependent oxidoreductase -
QUE38_RS16310 (GCM10025877_32920) 3414284..3415240 - 957 WP_286309378.1 hypothetical protein -
QUE38_RS16315 (GCM10025877_32930) 3415380..3415778 - 399 WP_286309379.1 type II toxin-antitoxin system VapC family toxin Toxin
QUE38_RS16320 (GCM10025877_32940) 3415778..3416032 - 255 WP_286309380.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QUE38_RS16325 3416133..3416645 + 513 WP_286309381.1 patatin-like phospholipase family protein -
QUE38_RS16330 (GCM10025877_32960) 3416564..3416968 + 405 WP_286309382.1 hypothetical protein -
QUE38_RS16335 (GCM10025877_32970) 3416968..3417447 + 480 WP_286309384.1 hypothetical protein -
QUE38_RS16340 (GCM10025877_32980) 3417456..3418001 + 546 WP_286309385.1 hypothetical protein -
QUE38_RS16345 (GCM10025877_32990) 3418011..3418514 - 504 WP_286309386.1 nitroreductase/quinone reductase family protein -
QUE38_RS16350 (GCM10025877_33000) 3418663..3419265 + 603 WP_286309387.1 DUF308 domain-containing protein -
QUE38_RS16355 (GCM10025877_33010) 3419287..3419955 - 669 WP_286309388.1 GAP family protein -
QUE38_RS16360 (GCM10025877_33020) 3420004..3420768 - 765 WP_286309389.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-127)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 13863.66 Da        Isoelectric Point: 5.4300

>T44152 WP_286309379.1 NZ_AP027737:c3415778-3415380 [Agromyces mangrovi]
MALVVDTSAVAAIVFGEPDALAFGEALIAHAGDVHISAATVLEARIVIESRQGSSGTQDLARLLDQVSAAIVPFDAQQTS
LATAAWQRYGKGRHAAGLNFGDCFSYALARHLGMPLLYKGDDFTHTDVHAAI

Download         Length: 399 bp

>T44152 NZ_AP027737:c3415778-3415380 [Agromyces mangrovi]
ATGGCACTCGTCGTCGACACATCAGCGGTGGCGGCGATCGTCTTTGGCGAGCCCGATGCCCTGGCCTTCGGGGAGGCGCT
CATCGCGCACGCCGGTGACGTCCACATCAGCGCGGCGACCGTTCTGGAAGCACGGATCGTGATCGAGAGTCGTCAAGGCT
CGAGTGGAACCCAAGACCTGGCCCGTTTGCTCGACCAGGTCTCCGCAGCGATCGTTCCGTTCGACGCTCAGCAGACATCG
CTTGCCACAGCGGCGTGGCAACGCTATGGCAAGGGACGGCACGCCGCCGGCCTGAACTTCGGCGACTGCTTCTCGTACGC
GCTCGCACGACACCTCGGCATGCCCCTGCTGTACAAGGGTGATGACTTCACCCACACGGACGTCCATGCCGCCATCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9270.43 Da        Isoelectric Point: 4.8950

>AT44152 WP_286309380.1 NZ_AP027737:c3416032-3415778 [Agromyces mangrovi]
MALNIKDPETDRIARELADATGESITVAARIAMEERLRRVRATDAQRAVRDEIAAIIARGRARAVLDDRSAEEIIGYDEH
GLPS

Download         Length: 255 bp

>AT44152 NZ_AP027737:c3416032-3415778 [Agromyces mangrovi]
ATGGCCCTGAACATCAAGGATCCGGAGACCGACCGGATCGCCCGCGAACTCGCGGACGCGACGGGGGAGAGCATCACGGT
CGCCGCCCGCATCGCCATGGAGGAGCGCCTGCGGCGCGTACGAGCGACCGACGCCCAACGCGCGGTCCGCGACGAGATCG
CAGCGATCATCGCGCGAGGTCGAGCGCGAGCAGTCCTCGACGATCGCAGCGCGGAAGAGATCATCGGCTACGACGAGCAC
GGCCTTCCGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References