Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1616272..1616882 Replicon chromosome
Accession NZ_AP027737
Organism Agromyces mangrovi strain NBRC 112812

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QUE38_RS07670 Protein ID WP_286311307.1
Coordinates 1616272..1616682 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QUE38_RS07675 Protein ID WP_286311308.1
Coordinates 1616667..1616882 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE38_RS07645 (GCM10025877_15340) 1611897..1612259 - 363 WP_286311297.1 YciI family protein -
QUE38_RS07650 (GCM10025877_15350) 1612379..1613191 - 813 WP_286311299.1 ABC transporter permease -
QUE38_RS07655 (GCM10025877_15360) 1613188..1614270 - 1083 WP_286311301.1 ATP-binding cassette domain-containing protein -
QUE38_RS07660 (GCM10025877_15370) 1614333..1615319 + 987 WP_286311303.1 YafY family protein -
QUE38_RS07665 (GCM10025877_15380) 1615332..1616201 - 870 WP_286311305.1 oxygenase MpaB family protein -
QUE38_RS07670 (GCM10025877_15390) 1616272..1616682 - 411 WP_286311307.1 PIN domain nuclease Toxin
QUE38_RS07675 (GCM10025877_15400) 1616667..1616882 - 216 WP_286311308.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QUE38_RS07680 (GCM10025877_15410) 1616947..1617708 - 762 WP_286311309.1 MBL fold metallo-hydrolase -
QUE38_RS07685 (GCM10025877_15420) 1617768..1618415 - 648 WP_286311311.1 YigZ family protein -
QUE38_RS07690 (GCM10025877_15430) 1618493..1619713 + 1221 WP_286311313.1 MFS transporter -
QUE38_RS07695 (GCM10025877_15450) 1619889..1620545 + 657 WP_286311315.1 fasciclin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-123)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(3-39)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14565.79 Da        Isoelectric Point: 4.8781

>T44149 WP_286311307.1 NZ_AP027737:c1616682-1616272 [Agromyces mangrovi]
MARPVILVDTSAWIEFLRDTDDPVVAELAEAIGSGTEVAITEPIVMELLAGATSAQLERSIGALVNGLPVVPVDGPLDYR
AAAQLSVASRRNGHPIRSLVDCLIAAVALRRGLTVLHRDRDFEFLAQVSPLRTRTA

Download         Length: 411 bp

>T44149 NZ_AP027737:c1616682-1616272 [Agromyces mangrovi]
TTGGCGCGACCAGTGATCCTCGTCGACACGTCGGCGTGGATCGAGTTCCTTCGCGATACCGACGACCCCGTCGTCGCGGA
GCTCGCCGAAGCGATCGGGTCCGGTACCGAGGTGGCGATCACCGAGCCGATCGTCATGGAGTTGCTCGCCGGTGCGACCT
CGGCGCAACTGGAGCGGAGCATCGGTGCGCTCGTGAACGGCCTGCCCGTCGTGCCGGTGGACGGTCCGCTCGACTACCGT
GCGGCGGCCCAGCTCTCCGTCGCCTCGCGCCGGAACGGGCACCCGATTCGAAGCCTCGTCGACTGCCTCATCGCGGCGGT
TGCGCTCCGTCGAGGGTTGACCGTGCTGCACCGGGACCGCGACTTCGAGTTCCTTGCCCAGGTCAGCCCACTGCGCACGC
GAACTGCGTGA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8050.93 Da        Isoelectric Point: 4.0994

>AT44149 WP_286311308.1 NZ_AP027737:c1616882-1616667 [Agromyces mangrovi]
MTRTNIDIDDELIAEAMSRFDLSTKREAVDFALRRLVGVQLTTEALLALRGSGWGGDVDEIRDDNDPWRDQ

Download         Length: 216 bp

>AT44149 NZ_AP027737:c1616882-1616667 [Agromyces mangrovi]
ATGACACGCACAAACATCGACATCGATGACGAGCTCATCGCCGAGGCGATGAGTCGGTTCGATCTTTCGACGAAGCGAGA
GGCCGTCGACTTCGCGCTGCGCCGATTGGTCGGGGTGCAGCTCACCACGGAGGCGCTGTTGGCGCTGCGCGGGAGCGGCT
GGGGTGGGGACGTCGACGAGATCCGCGACGACAATGACCCTTGGCGCGACCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References