Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 1307640..1308151 Replicon chromosome
Accession NZ_AP027737
Organism Agromyces mangrovi strain NBRC 112812

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag QUE38_RS06225 Protein ID WP_286310756.1
Coordinates 1307640..1307906 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QUE38_RS06230 Protein ID WP_286310757.1
Coordinates 1307903..1308151 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE38_RS06195 1303630..1303977 - 348 WP_286310752.1 hypothetical protein -
QUE38_RS06200 (GCM10025877_12440) 1304084..1305194 + 1111 Protein_1212 alcohol dehydrogenase catalytic domain-containing protein -
QUE38_RS06205 (GCM10025877_12450) 1305246..1305998 + 753 WP_286310753.1 SDR family oxidoreductase -
QUE38_RS06210 (GCM10025877_12460) 1306052..1306471 + 420 WP_286311678.1 MaoC family dehydratase -
QUE38_RS06215 (GCM10025877_12470) 1306619..1307071 + 453 WP_286310754.1 prevent-host-death protein -
QUE38_RS06220 (GCM10025877_12480) 1307143..1307646 + 504 WP_286310755.1 AAA family ATPase -
QUE38_RS06225 (GCM10025877_12490) 1307640..1307906 - 267 WP_286310756.1 Txe/YoeB family addiction module toxin Toxin
QUE38_RS06230 (GCM10025877_12500) 1307903..1308151 - 249 WP_286310757.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QUE38_RS06235 (GCM10025877_12510) 1308208..1309431 - 1224 WP_286310759.1 acetyl-CoA C-acetyltransferase -
QUE38_RS06240 (GCM10025877_12520) 1309523..1310725 - 1203 WP_286310762.1 acyl-CoA dehydrogenase family protein -
QUE38_RS06245 (GCM10025877_12530) 1310853..1311533 + 681 WP_286310764.1 QsdR family transcriptional regulator -
QUE38_RS06250 (GCM10025877_12540) 1311530..1312012 + 483 WP_286310766.1 thioesterase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10434.85 Da        Isoelectric Point: 7.1985

>T44148 WP_286310756.1 NZ_AP027737:c1307906-1307640 [Agromyces mangrovi]
VTARKLAWTADGWDDYLYWQTQDRKTLKRINLLIEDILRDDPFEGVGKPEPLKHALAGAWSRRIDEANRLVYTVTEQYVI
VLQARYHY

Download         Length: 267 bp

>T44148 NZ_AP027737:c1307906-1307640 [Agromyces mangrovi]
GTGACGGCGCGGAAGCTCGCCTGGACCGCCGACGGCTGGGACGACTACCTCTACTGGCAGACGCAGGACCGCAAGACCCT
CAAACGCATCAACCTGCTCATCGAGGACATACTGCGGGATGACCCGTTCGAGGGCGTCGGCAAGCCCGAGCCGCTCAAAC
ACGCGCTGGCCGGAGCATGGTCGCGGCGCATCGACGAAGCGAACCGCCTCGTCTACACGGTGACCGAGCAGTACGTGATC
GTGCTGCAGGCGCGCTACCACTACTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9348.51 Da        Isoelectric Point: 4.8668

>AT44148 WP_286310757.1 NZ_AP027737:c1308151-1307903 [Agromyces mangrovi]
MAITTSEARRDLFGLIERVNLDHTEVEITSKRGSAVLMSKAEYDSLLETTYLLRSPENARRLIRAMEQARDGEVTEHGLQ
EQ

Download         Length: 249 bp

>AT44148 NZ_AP027737:c1308151-1307903 [Agromyces mangrovi]
ATGGCCATCACCACGAGCGAGGCGCGCCGCGATCTCTTCGGTCTGATCGAGCGCGTGAACCTCGATCACACCGAGGTCGA
GATCACGTCGAAGCGCGGTTCCGCGGTGCTCATGTCCAAGGCGGAATACGACTCCCTGCTCGAGACCACCTACCTGCTCC
GCTCCCCGGAGAACGCCCGACGCCTCATCCGGGCGATGGAGCAGGCGCGCGATGGCGAGGTCACCGAGCACGGACTGCAG
GAGCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References