Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC(toxin) |
| Location | 3289698..3290335 | Replicon | chromosome |
| Accession | NZ_AP027735 | ||
| Organism | Barrientosiimonas endolithica strain NBRC 110608 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | QUE40_RS16595 | Protein ID | WP_289231663.1 |
| Coordinates | 3289698..3290090 (-) | Length | 131 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | QUE40_RS16600 | Protein ID | WP_142007043.1 |
| Coordinates | 3290087..3290335 (-) | Length | 83 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUE40_RS16560 | 3285678..3286693 | + | 1016 | Protein_3258 | LLM class flavin-dependent oxidoreductase | - |
| QUE40_RS16565 (GCM10025872_34390) | 3286778..3287215 | + | 438 | WP_289231657.1 | SRPBCC domain-containing protein | - |
| QUE40_RS16570 (GCM10025872_34400) | 3287212..3287535 | + | 324 | WP_289231658.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| QUE40_RS16575 (GCM10025872_34410) | 3287580..3287855 | - | 276 | WP_289231659.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| QUE40_RS16580 (GCM10025872_34420) | 3287852..3288121 | - | 270 | WP_289231660.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| QUE40_RS16585 (GCM10025872_34430) | 3288185..3289210 | - | 1026 | WP_289231661.1 | aldo/keto reductase | - |
| QUE40_RS16590 (GCM10025872_34440) | 3289207..3289653 | - | 447 | WP_289231662.1 | MerR family transcriptional regulator | - |
| QUE40_RS16595 (GCM10025872_34450) | 3289698..3290090 | - | 393 | WP_289231663.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| QUE40_RS16600 (GCM10025872_34460) | 3290087..3290335 | - | 249 | WP_142007043.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| QUE40_RS16605 (GCM10025872_34470) | 3290456..3291016 | - | 561 | WP_142007044.1 | YceI family protein | - |
| QUE40_RS16610 (GCM10025872_34480) | 3291105..3291593 | + | 489 | WP_289231664.1 | MarR family transcriptional regulator | - |
| QUE40_RS16615 (GCM10025872_34490) | 3291584..3292003 | - | 420 | WP_142007046.1 | VOC family protein | - |
| QUE40_RS16620 (GCM10025872_34500) | 3292160..3293611 | + | 1452 | WP_142007047.1 | insulinase family protein | - |
| QUE40_RS16625 (GCM10025872_34510) | 3293627..3294085 | - | 459 | WP_289233113.1 | GNAT family N-acetyltransferase | - |
| QUE40_RS16630 (GCM10025872_34520) | 3294101..3295162 | - | 1062 | WP_289231665.1 | NAD(P)-dependent alcohol dehydrogenase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 131 a.a. Molecular weight: 14057.91 Da Isoelectric Point: 4.6691
>T44146 WP_289231663.1 NZ_AP027735:c3290090-3289698 [Barrientosiimonas endolithica]
VIVDSSALVAVLNDEPRAQELVTLMRDRSTAMSAATYVEAAVVVDARRDPALSRQFDTLLSTLGIAVVDVTPEMAAVARQ
AYRDFGRGSGHAARLNFGDCFSYALAVVRDEPLLFVGDDFTHTDVRAALR
VIVDSSALVAVLNDEPRAQELVTLMRDRSTAMSAATYVEAAVVVDARRDPALSRQFDTLLSTLGIAVVDVTPEMAAVARQ
AYRDFGRGSGHAARLNFGDCFSYALAVVRDEPLLFVGDDFTHTDVRAALR
Download Length: 393 bp
>T44146 NZ_AP027735:c3290090-3289698 [Barrientosiimonas endolithica]
GTGATCGTCGACTCGTCCGCGCTGGTCGCCGTCCTCAACGACGAGCCCAGGGCGCAAGAGCTGGTGACGCTGATGCGTGA
CCGTTCGACGGCCATGTCCGCGGCCACCTACGTCGAGGCTGCGGTCGTGGTGGACGCCCGCCGAGATCCTGCGCTGTCCC
GCCAGTTCGACACCCTGCTGAGCACGCTCGGCATCGCCGTCGTGGACGTGACGCCCGAGATGGCGGCCGTGGCGCGGCAG
GCCTACCGCGACTTCGGCCGTGGCTCCGGGCACGCGGCACGACTCAACTTCGGGGACTGCTTCTCCTACGCGCTCGCCGT
CGTGCGTGACGAACCCCTCCTGTTCGTGGGCGACGACTTCACCCATACCGACGTCCGCGCGGCTCTTCGCTGA
GTGATCGTCGACTCGTCCGCGCTGGTCGCCGTCCTCAACGACGAGCCCAGGGCGCAAGAGCTGGTGACGCTGATGCGTGA
CCGTTCGACGGCCATGTCCGCGGCCACCTACGTCGAGGCTGCGGTCGTGGTGGACGCCCGCCGAGATCCTGCGCTGTCCC
GCCAGTTCGACACCCTGCTGAGCACGCTCGGCATCGCCGTCGTGGACGTGACGCCCGAGATGGCGGCCGTGGCGCGGCAG
GCCTACCGCGACTTCGGCCGTGGCTCCGGGCACGCGGCACGACTCAACTTCGGGGACTGCTTCTCCTACGCGCTCGCCGT
CGTGCGTGACGAACCCCTCCTGTTCGTGGGCGACGACTTCACCCATACCGACGTCCGCGCGGCTCTTCGCTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9165.20 Da Isoelectric Point: 4.6926
>AT44146 WP_142007043.1 NZ_AP027735:c3290335-3290087 [Barrientosiimonas endolithica]
MSLNIKNERVHDLVREVARRTGRSQTSAVELALERLLAELGREDDAGSQELDGLLADMRDRVSRTGGRLTTDELYDEAGL
PR
MSLNIKNERVHDLVREVARRTGRSQTSAVELALERLLAELGREDDAGSQELDGLLADMRDRVSRTGGRLTTDELYDEAGL
PR
Download Length: 249 bp
>AT44146 NZ_AP027735:c3290335-3290087 [Barrientosiimonas endolithica]
ATGAGCCTCAACATCAAGAACGAGCGTGTGCACGACCTCGTGCGTGAGGTGGCGCGGCGCACGGGTCGTTCCCAGACGAG
TGCCGTGGAGCTGGCGCTGGAGCGGTTGCTGGCAGAGCTGGGGCGCGAGGACGACGCCGGGAGCCAAGAGCTCGACGGGC
TGCTGGCTGACATGCGCGATCGCGTGAGCCGGACCGGCGGCCGGCTCACGACCGACGAGCTCTACGACGAGGCCGGCCTG
CCGCGGTGA
ATGAGCCTCAACATCAAGAACGAGCGTGTGCACGACCTCGTGCGTGAGGTGGCGCGGCGCACGGGTCGTTCCCAGACGAG
TGCCGTGGAGCTGGCGCTGGAGCGGTTGCTGGCAGAGCTGGGGCGCGAGGACGACGCCGGGAGCCAAGAGCTCGACGGGC
TGCTGGCTGACATGCGCGATCGCGTGAGCCGGACCGGCGGCCGGCTCACGACCGACGAGCTCTACGACGAGGCCGGCCTG
CCGCGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|