Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-YefM |
| Location | 3287580..3288121 | Replicon | chromosome |
| Accession | NZ_AP027735 | ||
| Organism | Barrientosiimonas endolithica strain NBRC 110608 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | QUE40_RS16575 | Protein ID | WP_289231659.1 |
| Coordinates | 3287580..3287855 (-) | Length | 92 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | QUE40_RS16580 | Protein ID | WP_289231660.1 |
| Coordinates | 3287852..3288121 (-) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QUE40_RS16545 (GCM10025872_34340) | 3282747..3283691 | + | 945 | WP_142007032.1 | WYL domain-containing protein | - |
| QUE40_RS16550 (GCM10025872_34350) | 3283720..3284373 | - | 654 | WP_142007033.1 | NAD(P)H-binding protein | - |
| QUE40_RS16555 (GCM10025872_34360) | 3284439..3285536 | - | 1098 | WP_289231656.1 | crosslink repair DNA glycosylase YcaQ family protein | - |
| QUE40_RS16560 | 3285678..3286693 | + | 1016 | Protein_3258 | LLM class flavin-dependent oxidoreductase | - |
| QUE40_RS16565 (GCM10025872_34390) | 3286778..3287215 | + | 438 | WP_289231657.1 | SRPBCC domain-containing protein | - |
| QUE40_RS16570 (GCM10025872_34400) | 3287212..3287535 | + | 324 | WP_289231658.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| QUE40_RS16575 (GCM10025872_34410) | 3287580..3287855 | - | 276 | WP_289231659.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| QUE40_RS16580 (GCM10025872_34420) | 3287852..3288121 | - | 270 | WP_289231660.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| QUE40_RS16585 (GCM10025872_34430) | 3288185..3289210 | - | 1026 | WP_289231661.1 | aldo/keto reductase | - |
| QUE40_RS16590 (GCM10025872_34440) | 3289207..3289653 | - | 447 | WP_289231662.1 | MerR family transcriptional regulator | - |
| QUE40_RS16595 (GCM10025872_34450) | 3289698..3290090 | - | 393 | WP_289231663.1 | type II toxin-antitoxin system VapC family toxin | - |
| QUE40_RS16600 (GCM10025872_34460) | 3290087..3290335 | - | 249 | WP_142007043.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| QUE40_RS16605 (GCM10025872_34470) | 3290456..3291016 | - | 561 | WP_142007044.1 | YceI family protein | - |
| QUE40_RS16610 (GCM10025872_34480) | 3291105..3291593 | + | 489 | WP_289231664.1 | MarR family transcriptional regulator | - |
| QUE40_RS16615 (GCM10025872_34490) | 3291584..3292003 | - | 420 | WP_142007046.1 | VOC family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10564.08 Da Isoelectric Point: 10.5554
>T44145 WP_289231659.1 NZ_AP027735:c3287855-3287580 [Barrientosiimonas endolithica]
VTESGWRVELAPGAIRSLGQLPEKVSSAIVEFVTRTLPSNPRRLSEPLRFELEGWHVARRGDYRVIVEIHEDQRVLLIGR
IEHRAHAYRQR
VTESGWRVELAPGAIRSLGQLPEKVSSAIVEFVTRTLPSNPRRLSEPLRFELEGWHVARRGDYRVIVEIHEDQRVLLIGR
IEHRAHAYRQR
Download Length: 276 bp
>T44145 NZ_AP027735:c3287855-3287580 [Barrientosiimonas endolithica]
GTGACCGAATCGGGCTGGCGTGTCGAGCTCGCTCCCGGGGCGATCCGGTCGCTGGGCCAGCTGCCCGAGAAGGTCTCGTC
CGCGATCGTGGAGTTCGTGACGCGCACCCTCCCCAGCAACCCTCGTCGACTGTCAGAGCCCTTGCGGTTCGAGCTGGAGG
GTTGGCACGTTGCTCGTCGGGGCGACTATCGGGTGATCGTCGAGATCCACGAAGACCAGCGGGTGCTTCTGATCGGTCGC
ATCGAGCACCGTGCGCATGCCTATCGACAGCGTTGA
GTGACCGAATCGGGCTGGCGTGTCGAGCTCGCTCCCGGGGCGATCCGGTCGCTGGGCCAGCTGCCCGAGAAGGTCTCGTC
CGCGATCGTGGAGTTCGTGACGCGCACCCTCCCCAGCAACCCTCGTCGACTGTCAGAGCCCTTGCGGTTCGAGCTGGAGG
GTTGGCACGTTGCTCGTCGGGGCGACTATCGGGTGATCGTCGAGATCCACGAAGACCAGCGGGTGCTTCTGATCGGTCGC
ATCGAGCACCGTGCGCATGCCTATCGACAGCGTTGA
Antitoxin
Download Length: 90 a.a. Molecular weight: 9571.67 Da Isoelectric Point: 4.8210
>AT44145 WP_289231660.1 NZ_AP027735:c3288121-3287852 [Barrientosiimonas endolithica]
MRSVALSEAKDKLSSLVDEAASTHEIIRITKHGHPAAVLMSADDLESLHETLRVLSTPGAVDELNQARVDFASGESVSGD
ELRQRYGLA
MRSVALSEAKDKLSSLVDEAASTHEIIRITKHGHPAAVLMSADDLESLHETLRVLSTPGAVDELNQARVDFASGESVSGD
ELRQRYGLA
Download Length: 270 bp
>AT44145 NZ_AP027735:c3288121-3287852 [Barrientosiimonas endolithica]
ATGAGGTCTGTGGCGCTGAGTGAGGCGAAAGACAAGTTGTCGTCTCTGGTCGACGAGGCGGCGAGCACTCACGAGATCAT
CCGCATCACCAAGCACGGGCACCCGGCTGCGGTGCTGATGTCGGCCGACGACCTGGAGTCGTTGCACGAGACGCTCCGGG
TGCTGTCCACGCCCGGCGCGGTCGACGAGCTCAACCAGGCTCGCGTCGACTTCGCGTCGGGCGAATCGGTGAGTGGGGAC
GAGCTGCGTCAGCGATACGGGTTGGCGTGA
ATGAGGTCTGTGGCGCTGAGTGAGGCGAAAGACAAGTTGTCGTCTCTGGTCGACGAGGCGGCGAGCACTCACGAGATCAT
CCGCATCACCAAGCACGGGCACCCGGCTGCGGTGCTGATGTCGGCCGACGACCTGGAGTCGTTGCACGAGACGCTCCGGG
TGCTGTCCACGCCCGGCGCGGTCGACGAGCTCAACCAGGCTCGCGTCGACTTCGCGTCGGGCGAATCGGTGAGTGGGGAC
GAGCTGCGTCAGCGATACGGGTTGGCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|